作为床旁检测设备的个人血糖仪的近期发展(2020-2024 年)

Biosensors Pub Date : 2024-08-27 DOI:10.3390/bios14090419
Dan-Ni Yang, Shan Geng, Rong Jing, Hao Zhang
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引用次数: 0

摘要

床旁检测(POCT)是一种现代诊断方法,其特点是方便用户、成本效益高、环境兼容、不依赖专业专家。因此,它被广泛应用于临床诊断和其他分析检测领域,以满足快速、便捷的检测需求。POCT 技术的应用不仅提高了检测效率,也为医疗行业带来了便利和效益。个人血糖仪(PGM)是一种非常成功的商用 POCT 工具,不仅广泛应用于葡萄糖分析,而且还用于非葡萄糖目标检测。本综述总结了 2020 年至 2024 年作为 POCT 设备的 PGM 在非葡萄糖目标分析方面的最新进展。简要介绍了基于 PGMs 的非葡萄糖目标分析的信号转导策略,包括酶转导、纳米载体转导(酶或葡萄糖)和葡萄糖消耗转导。同时,概述了 PGMs 在非葡萄糖目标分析中的应用,包括生物医学、环境和食品分析以及其他各种应用。最后,讨论了将 PGMs 作为 POCT 工具用于非葡萄糖目标分析的前景和障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent Developments in Personal Glucose Meters as Point-of-Care Testing Devices (2020–2024)
Point-of-care testing (POCT) is a contemporary diagnostic approach characterized by its user-friendly nature, cost efficiency, environmental compatibility, and lack of reliance on professional experts. Therefore, it is widely used in clinical diagnosis and other analytical testing fields to meet the demand for rapid and convenient testing. The application of POCT technology not only improves testing efficiency, but also brings convenience and benefits to the healthcare industry. The personal glucose meter (PGM) is a highly successful commercial POCT tool that has been widely used not only for glucose analysis, but also for non-glucose target detection. In this review, the recent advances from 2020 to 2024 in non-glucose target analysis for PGMs as POCT devices are summarized. The signal transduction strategies for non-glucose target analysis based on PGMs, including enzymatic transduction, nanocarrier transduction (enzyme or glucose), and glucose consumption transduction are briefly introduced. Meanwhile, the applications of PGMs in non-glucose target analysis are outlined, encompassing biomedical, environmental, and food analysis, along with other diverse applications. Finally, the prospects of and obstacles to employing PGMs as POCT tools for non-glucose target analysis are discussed.
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