O. G. Shakirova, T. A. Kuz’menko, N. V. Kurat’eva, L. S. Klyushova, A. N. Lavrov, L. G. Lavrenova
{"title":"3d 金属与 2,4-二甲基吡唑并[1,5-а]苯并咪唑的配位化合物：磁性和生物特性","authors":"O. G. Shakirova, T. A. Kuz’menko, N. V. Kurat’eva, L. S. Klyushova, A. N. Lavrov, L. G. Lavrenova","doi":"10.1134/S1070328424600621","DOIUrl":null,"url":null,"abstract":"<p>New coordination compounds of copper(I), copper(II), cobalt(II), and nickel(II) with 2,4-dimethylpyrazolo[1,5-а]benzimidazole (L) were synthesized and studied. The complexes [CuLCl] (<b>I</b>), [CuLBr] (<b>II</b>), [CuL<sub>2</sub>Cl<sub>2</sub>] (<b>III</b>), [CuL<sub>2</sub>(NO<sub>3</sub>)<sub>2</sub>]·H<sub>2</sub>O (<b>IV</b>), [CoL<sub>2</sub>Cl<sub>2</sub>]·0.5H<sub>2</sub>O (<b>V</b>), [CoL<sub>2</sub>(NO<sub>3</sub>)<sub>2</sub>]·0.5H<sub>2</sub>O (<b>VI</b>), and [NiL<sub>2</sub>(NO<sub>3</sub>)<sub>2</sub>]·0.5H<sub>2</sub>O (<b>VII</b>) were studied by IR spectroscopy and powder and single crystal X-ray diffraction (CCDC nos. 2321779 ([CuL<sub>2</sub>Cl<sub>2</sub>]), 2321780 ([CoL<sub>2</sub>(NO<sub>3</sub>)<sub>2</sub>])). The results indicate that the coordination polyhedron in 2,4-dimethylpyrazolo[1,5-а]benzimidazole complexes is formed by the nitrogen atoms of the monodentate ligand and the coordinated anion. The cytotoxic and cytostatic properties of L and complexes <b>I</b>–<b>III</b> were studied in relation to the HepG2 hepatocellular carcinoma cells.</p>","PeriodicalId":759,"journal":{"name":"Russian Journal of Coordination Chemistry","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Coordination Compounds of 3d Metals with 2,4-Dimethylpyrazolo[1,5-а]benzimidazole: Magnetic and Biological Properties\",\"authors\":\"O. G. Shakirova, T. A. Kuz’menko, N. V. Kurat’eva, L. S. Klyushova, A. N. Lavrov, L. G. Lavrenova\",\"doi\":\"10.1134/S1070328424600621\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>New coordination compounds of copper(I), copper(II), cobalt(II), and nickel(II) with 2,4-dimethylpyrazolo[1,5-а]benzimidazole (L) were synthesized and studied. The complexes [CuLCl] (<b>I</b>), [CuLBr] (<b>II</b>), [CuL<sub>2</sub>Cl<sub>2</sub>] (<b>III</b>), [CuL<sub>2</sub>(NO<sub>3</sub>)<sub>2</sub>]·H<sub>2</sub>O (<b>IV</b>), [CoL<sub>2</sub>Cl<sub>2</sub>]·0.5H<sub>2</sub>O (<b>V</b>), [CoL<sub>2</sub>(NO<sub>3</sub>)<sub>2</sub>]·0.5H<sub>2</sub>O (<b>VI</b>), and [NiL<sub>2</sub>(NO<sub>3</sub>)<sub>2</sub>]·0.5H<sub>2</sub>O (<b>VII</b>) were studied by IR spectroscopy and powder and single crystal X-ray diffraction (CCDC nos. 2321779 ([CuL<sub>2</sub>Cl<sub>2</sub>]), 2321780 ([CoL<sub>2</sub>(NO<sub>3</sub>)<sub>2</sub>])). The results indicate that the coordination polyhedron in 2,4-dimethylpyrazolo[1,5-а]benzimidazole complexes is formed by the nitrogen atoms of the monodentate ligand and the coordinated anion. The cytotoxic and cytostatic properties of L and complexes <b>I</b>–<b>III</b> were studied in relation to the HepG2 hepatocellular carcinoma cells.</p>\",\"PeriodicalId\":759,\"journal\":{\"name\":\"Russian Journal of Coordination Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2024-08-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Coordination Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1070328424600621\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Coordination Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070328424600621","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Coordination Compounds of 3d Metals with 2,4-Dimethylpyrazolo[1,5-а]benzimidazole: Magnetic and Biological Properties
New coordination compounds of copper(I), copper(II), cobalt(II), and nickel(II) with 2,4-dimethylpyrazolo[1,5-а]benzimidazole (L) were synthesized and studied. The complexes [CuLCl] (I), [CuLBr] (II), [CuL2Cl2] (III), [CuL2(NO3)2]·H2O (IV), [CoL2Cl2]·0.5H2O (V), [CoL2(NO3)2]·0.5H2O (VI), and [NiL2(NO3)2]·0.5H2O (VII) were studied by IR spectroscopy and powder and single crystal X-ray diffraction (CCDC nos. 2321779 ([CuL2Cl2]), 2321780 ([CoL2(NO3)2])). The results indicate that the coordination polyhedron in 2,4-dimethylpyrazolo[1,5-а]benzimidazole complexes is formed by the nitrogen atoms of the monodentate ligand and the coordinated anion. The cytotoxic and cytostatic properties of L and complexes I–III were studied in relation to the HepG2 hepatocellular carcinoma cells.
期刊介绍：
Russian Journal of Coordination Chemistry is a journal that publishes reviews, original papers, and short communications on all aspects of theoretical and experimental coordination chemistry. Modern coordination chemistry is an interdisciplinary science that makes a bridge between inorganic, organic, physical, analytical, and biological chemistry.
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