嗜卤古细菌 Halobacterium salinarum 的培养

IF 0.4 Q4 PHYSICS, PARTICLES & FIELDS

Physics of Particles and Nuclei Letters Pub Date : 2024-08-14 DOI:10.1134/s1547477124701449

D. D. Kuklina, A. Yu. Shishkin, I. O. Bezruchko, S. V. Kalenov, I. S. Okhrimenko, E. A. Dronova, A. E. Mikhailov, Yu. L. Ryzhykau

{"title":"嗜卤古细菌 Halobacterium salinarum 的培养","authors":"D. D. Kuklina, A. Yu. Shishkin, I. O. Bezruchko, S. V. Kalenov, I. S. Okhrimenko, E. A. Dronova, A. E. Mikhailov, Yu. L. Ryzhykau","doi":"10.1134/s1547477124701449","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3>A light-sensitive protein from extremophile archaea Halobacterium salinarum, bacteriorhodopsin (HsBR), has found numerous applications in pharmacology, biotechnology, bioelectronics and other fields [1, 2] due to its ability to convert light energy into a gradient of hydrogen ions across the cell membrane. Despite a wide range of its practical applications, the quantum mechanism of proton transfer remains not fully discovered yet. For further investigation and cost-effective implementation of developments, a higher yield of BR-rich biomass is necessitated. Hereafter we present our findings regarding efficient synthesis of HsBR using its natural host, H. salinarum.","PeriodicalId":730,"journal":{"name":"Physics of Particles and Nuclei Letters","volume":"64 1","pages":""},"PeriodicalIF":0.4000,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cultivation of Halophilic Archaea Halobacterium salinarum\",\"authors\":\"D. D. Kuklina, A. Yu. Shishkin, I. O. Bezruchko, S. V. Kalenov, I. S. Okhrimenko, E. A. Dronova, A. E. Mikhailov, Yu. L. Ryzhykau\",\"doi\":\"10.1134/s1547477124701449\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<h3 data-test=\\\"abstract-sub-heading\\\">Abstract</h3>A light-sensitive protein from extremophile archaea Halobacterium salinarum, bacteriorhodopsin (HsBR), has found numerous applications in pharmacology, biotechnology, bioelectronics and other fields [1, 2] due to its ability to convert light energy into a gradient of hydrogen ions across the cell membrane. Despite a wide range of its practical applications, the quantum mechanism of proton transfer remains not fully discovered yet. For further investigation and cost-effective implementation of developments, a higher yield of BR-rich biomass is necessitated. Hereafter we present our findings regarding efficient synthesis of HsBR using its natural host, H. salinarum.\",\"PeriodicalId\":730,\"journal\":{\"name\":\"Physics of Particles and Nuclei Letters\",\"volume\":\"64 1\",\"pages\":\"\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2024-08-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physics of Particles and Nuclei Letters\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1134/s1547477124701449\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHYSICS, PARTICLES & FIELDS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics of Particles and Nuclei Letters","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1134/s1547477124701449","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHYSICS, PARTICLES & FIELDS","Score":null,"Total":0}

引用次数: 0

摘要

摘要一种来自嗜极古菌 Halobacterium salinarum 的光敏蛋白--细菌性钠光蛋白（bacteriorhodopsin，HsBR），由于能够将光能转化为跨细胞膜的氢离子梯度，已经在药理学、生物技术、生物电子学等领域得到了广泛的应用[1, 2]。尽管质子传递具有广泛的实际应用，但其量子机制仍未被完全发现。为了进一步研究和实现具有成本效益的开发，必须提高富含 BR 的生物质的产量。下面我们将介绍利用天然宿主 H. salinarum 高效合成 HsBR 的研究成果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Cultivation of Halophilic Archaea Halobacterium salinarum

查看原文本刊更多论文

Cultivation of Halophilic Archaea Halobacterium salinarum

Abstract

A light-sensitive protein from extremophile archaea Halobacterium salinarum, bacteriorhodopsin (HsBR), has found numerous applications in pharmacology, biotechnology, bioelectronics and other fields [1, 2] due to its ability to convert light energy into a gradient of hydrogen ions across the cell membrane. Despite a wide range of its practical applications, the quantum mechanism of proton transfer remains not fully discovered yet. For further investigation and cost-effective implementation of developments, a higher yield of BR-rich biomass is necessitated. Hereafter we present our findings regarding efficient synthesis of HsBR using its natural host, H. salinarum.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Physics of Particles and Nuclei Letters PHYSICS, PARTICLES & FIELDS-

CiteScore

0.80

自引率

20.00%

发文量

108

期刊介绍： The journal Physics of Particles and Nuclei Letters, brief name Particles and Nuclei Letters, publishes the articles with results of the original theoretical, experimental, scientific-technical, methodological and applied research. Subject matter of articles covers: theoretical physics, elementary particle physics, relativistic nuclear physics, nuclear physics and related problems in other branches of physics, neutron physics, condensed matter physics, physics and engineering at low temperatures, physics and engineering of accelerators, physical experimental instruments and methods, physical computation experiments, applied research in these branches of physics and radiology, ecology and nuclear medicine.