{"title":"设计基于质子加速器的硼中子俘获疗法的束流整形组件中的混合材料慢化剂","authors":"","doi":"10.1016/j.apradiso.2024.111515","DOIUrl":null,"url":null,"abstract":"<div><p>Boron Neutron Capture Therapy is being promoted with the development of accelerator neutron sources, and many new accelerator-based BNCT facilities are being built. In Particle Accelerator Facility project of Sun Yat-sen University, we plan to build a terminal for BNCT research based on an 8 MeV, CW 3 mA proton accelerator. In this paper, we present a beam-shaping assembly for this proton accelerator with such low 24 kW beam power, using composite moderator materials composed of five elements: Mg, Al, F, O, and Li. The calculation result of FLUKA with ENDF/B and JENDL libraries shows that the epithermal neutron beam flux is <span><math><mrow><mn>1.57</mn><mo>×</mo><msup><mn>10</mn><mn>9</mn></msup><mi>n</mi><mo>/</mo><msup><mtext>cm</mtext><mn>2</mn></msup><mo>/</mo><mi>s</mi></mrow></math></span> with the CW 3 mA proton beam. The fast neutron component and the gamma ray component under free-air condition are <span><math><mrow><mn>1.49</mn><mo>×</mo><msup><mn>10</mn><mrow><mo>−</mo><mn>13</mn></mrow></msup><mspace></mspace><mtext>Gy</mtext><mo>∙</mo><msup><mtext>cm</mtext><mn>2</mn></msup></mrow></math></span> and <span><math><mrow><mn>8.12</mn><mo>×</mo><msup><mn>10</mn><mrow><mo>−</mo><mn>14</mn></mrow></msup><mspace></mspace><mtext>Gy</mtext><mo>∙</mo><msup><mtext>cm</mtext><mn>2</mn></msup></mrow></math></span> respectively, in line with IAEA-TECDOC-1223 design recommendations. The thermal analysis shows that the maximum temperature of beryllium target is 706.5 K, and the structure materials of BSA do not melt.</p></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Design of a mixed material moderator in a beam-shaping assembly for proton accelerator-based boron neutron capture therapy\",\"authors\":\"\",\"doi\":\"10.1016/j.apradiso.2024.111515\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Boron Neutron Capture Therapy is being promoted with the development of accelerator neutron sources, and many new accelerator-based BNCT facilities are being built. In Particle Accelerator Facility project of Sun Yat-sen University, we plan to build a terminal for BNCT research based on an 8 MeV, CW 3 mA proton accelerator. In this paper, we present a beam-shaping assembly for this proton accelerator with such low 24 kW beam power, using composite moderator materials composed of five elements: Mg, Al, F, O, and Li. The calculation result of FLUKA with ENDF/B and JENDL libraries shows that the epithermal neutron beam flux is <span><math><mrow><mn>1.57</mn><mo>×</mo><msup><mn>10</mn><mn>9</mn></msup><mi>n</mi><mo>/</mo><msup><mtext>cm</mtext><mn>2</mn></msup><mo>/</mo><mi>s</mi></mrow></math></span> with the CW 3 mA proton beam. The fast neutron component and the gamma ray component under free-air condition are <span><math><mrow><mn>1.49</mn><mo>×</mo><msup><mn>10</mn><mrow><mo>−</mo><mn>13</mn></mrow></msup><mspace></mspace><mtext>Gy</mtext><mo>∙</mo><msup><mtext>cm</mtext><mn>2</mn></msup></mrow></math></span> and <span><math><mrow><mn>8.12</mn><mo>×</mo><msup><mn>10</mn><mrow><mo>−</mo><mn>14</mn></mrow></msup><mspace></mspace><mtext>Gy</mtext><mo>∙</mo><msup><mtext>cm</mtext><mn>2</mn></msup></mrow></math></span> respectively, in line with IAEA-TECDOC-1223 design recommendations. The thermal analysis shows that the maximum temperature of beryllium target is 706.5 K, and the structure materials of BSA do not melt.</p></div>\",\"PeriodicalId\":8096,\"journal\":{\"name\":\"Applied Radiation and Isotopes\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Radiation and Isotopes\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0969804324003439\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Radiation and Isotopes","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0969804324003439","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Design of a mixed material moderator in a beam-shaping assembly for proton accelerator-based boron neutron capture therapy
Boron Neutron Capture Therapy is being promoted with the development of accelerator neutron sources, and many new accelerator-based BNCT facilities are being built. In Particle Accelerator Facility project of Sun Yat-sen University, we plan to build a terminal for BNCT research based on an 8 MeV, CW 3 mA proton accelerator. In this paper, we present a beam-shaping assembly for this proton accelerator with such low 24 kW beam power, using composite moderator materials composed of five elements: Mg, Al, F, O, and Li. The calculation result of FLUKA with ENDF/B and JENDL libraries shows that the epithermal neutron beam flux is with the CW 3 mA proton beam. The fast neutron component and the gamma ray component under free-air condition are and respectively, in line with IAEA-TECDOC-1223 design recommendations. The thermal analysis shows that the maximum temperature of beryllium target is 706.5 K, and the structure materials of BSA do not melt.
期刊介绍:
Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment.
The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria.
Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.