{"title":"用肌酸-CEST 绘制棕色脂肪图。","authors":"Mohammed K Hankir","doi":"10.1016/j.tem.2024.08.013","DOIUrl":null,"url":null,"abstract":"Accurate assessment of brown fat thermogenesis by non-invasive means remains challenging. Writing in Nature Metabolism, Cai et al. leverage the futile creatine cycling characteristic of thermogenic adipocytes to show that a type of magnetic resonance imaging (MRI) technique sensitive to endogenous creatine levels faithfully tracks brown fat thermogenesis in rodents and in humans.","PeriodicalId":23301,"journal":{"name":"Trends in Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Creating a picture of brown fat with creatine-CEST.\",\"authors\":\"Mohammed K Hankir\",\"doi\":\"10.1016/j.tem.2024.08.013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Accurate assessment of brown fat thermogenesis by non-invasive means remains challenging. Writing in Nature Metabolism, Cai et al. leverage the futile creatine cycling characteristic of thermogenic adipocytes to show that a type of magnetic resonance imaging (MRI) technique sensitive to endogenous creatine levels faithfully tracks brown fat thermogenesis in rodents and in humans.\",\"PeriodicalId\":23301,\"journal\":{\"name\":\"Trends in Endocrinology & Metabolism\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Endocrinology & Metabolism\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.tem.2024.08.013\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Endocrinology & Metabolism","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.tem.2024.08.013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Creating a picture of brown fat with creatine-CEST.
Accurate assessment of brown fat thermogenesis by non-invasive means remains challenging. Writing in Nature Metabolism, Cai et al. leverage the futile creatine cycling characteristic of thermogenic adipocytes to show that a type of magnetic resonance imaging (MRI) technique sensitive to endogenous creatine levels faithfully tracks brown fat thermogenesis in rodents and in humans.
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