电子液体分析:使用气相色谱-质谱法和电感耦合等离子体-质谱法研究化学多样性和金属含量

IF 2.8 3区 工程技术 Q2 CHEMISTRY, ANALYTICAL
Matjaž Rantaša, David Majer, Matjaž Finšgar
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引用次数: 0

摘要

这项研究旨在确定斯洛文尼亚市场上 22 种电子液体的化学成分。在定性分析中采用了四种不同的气相色谱(GC)样品导入技术:顶空气相色谱-质谱联用仪(HS-GC-MS)、液体注射气相色谱-质谱联用仪(LI-GC-MS)、HS-固相微萃取气相色谱-质谱联用仪(HS-SPME-GC-MS)和直接浸没-SPME-气相色谱-质谱联用仪(DI-SPME-GC-MS)。对每种气相色谱样品引入技术的各种实验参数进行了评估,以最大限度地鉴定化合物。尽管电子液体包装上报告的化合物最多为 8 种,但 GC-MS 在大多数样品中鉴定出了更多的化合物,尤其是薄荷味样品(HS-SPME-GC-MS 鉴定出 58 种化合物),其次是含尼古丁和水果味样品。HS-SPME-GC-MS 鉴定出的化合物数量最多,其次是 HS-GC-MS、DI-SPME-GC-MS 和 LI-GC-MS。在甲醇中稀释后,采用 LI-GC-MS 对六个样品中的尼古丁进行了定量。样品中的尼古丁浓度介于 16.5 ± 0.5 至 18.5 ± 0.4 毫克/毫升之间,低于 20 毫克/毫升的申报浓度。此外,在微波辅助湿酸消解后,采用电感耦合等离子体质谱仪对电子液体中的金属进行了定量分析。铁是含量最高的金属,其含量从 0.024 微克/克到 0.354 微克/克不等。在几种电子液体中还检测到钡、铋、铜和锡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The analysis of e-liquids: A study on chemical diversity and metal content using gas chromatography-mass spectrometry and inductively coupled plasma-mass spectrometry

The analysis of e-liquids: A study on chemical diversity and metal content using gas chromatography-mass spectrometry and inductively coupled plasma-mass spectrometry

This work aimed to determine the chemical composition of 22 e-liquids available on the Slovenian market. Four different gas chromatography (GC) sample introduction techniques; headspace-GC-mass spectrometry (HS-GC-MS), liquid injection-GC-MS (LI-GC-MS), HS-solid-phase microextraction-GC-MS (HS-SPME-GC-MS), and direct-immersion-SPME-GC-MS (DI-SPME-GC-MS) were employed for qualitative analysis. Various experimental parameters were assessed for each GC sample introduction technique to maximize compound identification. Despite e-liquid packaging reporting a maximum of eight compounds, GC-MS identified more compounds in most samples, especially in menthol-flavored (58 identifiable compounds by HS-SPME-GC-MS), followed by nicotine-containing and fruit-flavored samples. HS-SPME-GC-MS identified the highest number of compounds, followed by HS-GC-MS, DI-SPME-GC-MS, and LI-GC-MS. Nicotine quantification in six samples was performed by LI-GC-MS with dilution in methanol. Nicotine concentration in samples ranged from 16.5 ± 0.5 to 18.5 ± 0.4 mg/mL, which was below the declared concentration of 20 mg/mL. Additionally, quantitative analysis of metals in e-liquids was performed by inductively coupled plasma-MS after microwave-assisted wet acid digestion. Iron was the most abundant metal, with its content ranging from 0.024 to 0.354 µg/g. Barium, bismuth, copper, and tin were also determined in several e-liquids.

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来源期刊
Journal of separation science
Journal of separation science 化学-分析化学
CiteScore
6.30
自引率
16.10%
发文量
408
审稿时长
1.8 months
期刊介绍: The Journal of Separation Science (JSS) is the most comprehensive source in separation science, since it covers all areas of chromatographic and electrophoretic separation methods in theory and practice, both in the analytical and in the preparative mode, solid phase extraction, sample preparation, and related techniques. Manuscripts on methodological or instrumental developments, including detection aspects, in particular mass spectrometry, as well as on innovative applications will also be published. Manuscripts on hyphenation, automation, and miniaturization are particularly welcome. Pre- and post-separation facets of a total analysis may be covered as well as the underlying logic of the development or application of a method.
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