{"title":"用于治疗细菌感染伤口的铜基纳米材料:材料分类、策略和机制","authors":"","doi":"10.1016/j.ccr.2024.216205","DOIUrl":null,"url":null,"abstract":"<div><p>Bacterial infection in wounds is a complex and multilayered process, increasing the complexity and challenges of treatment. It often leads to infection, a deeper inflammatory response and a multifaceted slowing down of the wound repair process. Therefore, addressing these unique challenges requires focused and effective treatment strategies aimed at achieving optimal therapeutic outcomes and preventing complications. With rapid advancements in nanomaterials, catalytic techniques, and biotechnology, copper-based nanomaterials, as commonly used nanomaterials, exhibit excellent physicochemical properties, such as efficient catalytic, optical, thermal, or electrical characteristics, and are widely applied in wound management. To develop efficient and mature therapies for bacterial infection in wounds, a comprehensive understanding of the treatment strategies and mechanisms of copper-based nanomaterials in this context is essential. In this review, we systematically summarize the progress in the use of copper-based nanomaterials for treating bacterial infection in wounds, including the types of materials, treatment strategies, and mechanisms of action. We emphasize the unique advantages of different types of copper-based materials in treatment, diverse treatment modalities, and their mechanisms in terms of antibacterial, anti-inflammatory, or wound healing promotion. Finally, we discuss current challenges and the understanding and perspectives that have the potential to contribute to the development of treatments for bacterially infected wounds.</p></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":null,"pages":null},"PeriodicalIF":20.3000,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Copper-based nanomaterials for the treatment of bacteria-infected wounds: material classification, strategies and mechanisms\",\"authors\":\"\",\"doi\":\"10.1016/j.ccr.2024.216205\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Bacterial infection in wounds is a complex and multilayered process, increasing the complexity and challenges of treatment. It often leads to infection, a deeper inflammatory response and a multifaceted slowing down of the wound repair process. Therefore, addressing these unique challenges requires focused and effective treatment strategies aimed at achieving optimal therapeutic outcomes and preventing complications. With rapid advancements in nanomaterials, catalytic techniques, and biotechnology, copper-based nanomaterials, as commonly used nanomaterials, exhibit excellent physicochemical properties, such as efficient catalytic, optical, thermal, or electrical characteristics, and are widely applied in wound management. To develop efficient and mature therapies for bacterial infection in wounds, a comprehensive understanding of the treatment strategies and mechanisms of copper-based nanomaterials in this context is essential. In this review, we systematically summarize the progress in the use of copper-based nanomaterials for treating bacterial infection in wounds, including the types of materials, treatment strategies, and mechanisms of action. We emphasize the unique advantages of different types of copper-based materials in treatment, diverse treatment modalities, and their mechanisms in terms of antibacterial, anti-inflammatory, or wound healing promotion. Finally, we discuss current challenges and the understanding and perspectives that have the potential to contribute to the development of treatments for bacterially infected wounds.</p></div>\",\"PeriodicalId\":289,\"journal\":{\"name\":\"Coordination Chemistry Reviews\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":20.3000,\"publicationDate\":\"2024-09-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Coordination Chemistry Reviews\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0010854524005514\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Coordination Chemistry Reviews","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0010854524005514","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Copper-based nanomaterials for the treatment of bacteria-infected wounds: material classification, strategies and mechanisms
Bacterial infection in wounds is a complex and multilayered process, increasing the complexity and challenges of treatment. It often leads to infection, a deeper inflammatory response and a multifaceted slowing down of the wound repair process. Therefore, addressing these unique challenges requires focused and effective treatment strategies aimed at achieving optimal therapeutic outcomes and preventing complications. With rapid advancements in nanomaterials, catalytic techniques, and biotechnology, copper-based nanomaterials, as commonly used nanomaterials, exhibit excellent physicochemical properties, such as efficient catalytic, optical, thermal, or electrical characteristics, and are widely applied in wound management. To develop efficient and mature therapies for bacterial infection in wounds, a comprehensive understanding of the treatment strategies and mechanisms of copper-based nanomaterials in this context is essential. In this review, we systematically summarize the progress in the use of copper-based nanomaterials for treating bacterial infection in wounds, including the types of materials, treatment strategies, and mechanisms of action. We emphasize the unique advantages of different types of copper-based materials in treatment, diverse treatment modalities, and their mechanisms in terms of antibacterial, anti-inflammatory, or wound healing promotion. Finally, we discuss current challenges and the understanding and perspectives that have the potential to contribute to the development of treatments for bacterially infected wounds.
期刊介绍:
Coordination Chemistry Reviews offers rapid publication of review articles on current and significant topics in coordination chemistry, encompassing organometallic, supramolecular, theoretical, and bioinorganic chemistry. It also covers catalysis, materials chemistry, and metal-organic frameworks from a coordination chemistry perspective. Reviews summarize recent developments or discuss specific techniques, welcoming contributions from both established and emerging researchers.
The journal releases special issues on timely subjects, including those featuring contributions from specific regions or conferences. Occasional full-length book articles are also featured. Additionally, special volumes cover annual reviews of main group chemistry, transition metal group chemistry, and organometallic chemistry. These comprehensive reviews are vital resources for those engaged in coordination chemistry, further establishing Coordination Chemistry Reviews as a hub for insightful surveys in inorganic and physical inorganic chemistry.