CUP 的新临床试验和癌症分类的新范例

IF 81.1 1区医学 Q1 ONCOLOGY

Nature Reviews Clinical Oncology Pub Date : 2024-09-11 DOI:10.1038/s41571-024-00942-7

Elie Rassy, Fabrice André

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引用次数: 0

摘要

精准肿瘤学已经达到了一个里程碑，在两项试验中，分子图谱指导了特定部位和肿瘤诊断疗法，试验数据表明，原发灶不明癌症患者的生存率有所提高。这些研究结果还可以推而广之，支持在一般情况下使用组织诊断方法，并表明原发组织可能在癌症的不可知论分类及其对治疗的反应中发挥作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

New clinical trials in CUP and a novel paradigm in cancer classification

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New clinical trials in CUP and a novel paradigm in cancer classification

Precision oncology has reached a milestone as data from two trials in which molecular profiling guided both site-specific and tumour-agnostic therapies indicate improved survival outcomes in patients with cancer of unknown primary. These findings can also be extrapolated and support the use of tissue-agnostic approaches in general, and also suggest that the tissue of origin might have a role in the agnostic classification of cancers and their response to treatment.

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来源期刊

Nature Reviews Clinical Oncology 医学-肿瘤学

CiteScore

99.40

自引率

0.40%

发文量

114

审稿时长

6-12 weeks

期刊介绍： Nature Reviews publishes clinical content authored by internationally renowned clinical academics and researchers, catering to readers in the medical sciences at postgraduate levels and beyond. Although targeted at practicing doctors, researchers, and academics within specific specialties, the aim is to ensure accessibility for readers across various medical disciplines. The journal features in-depth Reviews offering authoritative and current information, contextualizing topics within the history and development of a field. Perspectives, News & Views articles, and the Research Highlights section provide topical discussions, opinions, and filtered primary research from diverse medical journals.