膝关节置换术的术前静息痛和运动诱发痛测量:一项前瞻性多中心纵向队列研究得出的疼痛与功能结果轨迹的关联。

IF 3.5 2区 医学 Q1 ANESTHESIOLOGY
Daniel L Riddle, Levent Dumenci
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引用次数: 0

摘要

背景:对肌肉骨骼疼痛患者静息痛(PAR)和运动诱发痛(MEP)的研究受到了广泛关注。尽管人们对其兴趣浓厚,但对其心理计量学发展的关注却相对较少。我们的目的是探索 PAR 和 MEP 之间的关系,并研究这些测量指标在膝关节置换术患者中的预后效用:我们使用了前瞻性收集的数据,这些数据来自计划接受膝关节置换术的患者,他们的疼痛灾难化程度为中度到高度。我们开发了PAR和MEP的术前潜变量,用于确定它们是否与疼痛和功能结果轨迹好坏的二元潜变量相关。使用因子相关性来确定 PAR 和 MEP 的方差重叠程度:结果:PAR 和 MEP 可显著预测疼痛和功能程度的好坏。比值比从 1.21 到 1.64 不等(p 结论:PAR 和 MEP 在疼痛和功能分级中具有重要的预测作用:根据我们研究的定义,PAR 和 MEP 可用于判断膝关节置换术后不良预后的风险轨迹。然而,PAR 和 MEP 显示的方差有很大的重叠,这表明在进行预后评估时没有必要同时测量 PAR 和 MEP:意义说明:根据我们研究的定义,术前 PAR 和 MEP 潜变量对 1 年的疼痛和功能结果轨迹具有预后意义。PAR和MEP潜变量的方差有很大程度的重叠,这表明在进行预后判断时只需要一个潜变量。在膝关节置换术的预后研究领域,PAR 和 MEP 的预后意义及其方差的大幅重叠是一项新发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preoperative measures of pain at rest and movement-evoked pain in knee arthroplasty: Associations with pain and function outcome trajectories from a prospective multicentre longitudinal cohort study.

Background: The study of pain at rest (PAR) and movement-evoked pain (MEP) in persons with musculoskeletal pain has received substantial attention. Despite strong interest, relatively little attention has been directed to the psychometric development of these constructs. Our purpose was to explore the relationship between PAR and MEP and to examine the prognostic utility of these measures in persons with knee arthroplasty.

Methods: We used prospectively collected data from persons scheduled for knee arthroplasty who had moderate to high levels of pain catastrophizing. Preoperative latent variables for PAR and MEP were developed and used to determine if they were associated with a binary latent variable of good versus poor pain and function outcome trajectories. Factor correlations were used to determine the extent to which the variance for PAR and MEP was overlapping.

Results: PAR and MEP are significant predictors of good versus poor pain and function classes. Odds ratios ranged from 1.21 to 1.64 (p < 0.001) indicating a significant increase in the likelihood of poor outcome. Correlation between PAR and MEP latent variables was high (r = 0.89; 95% CI: 0.86-0.92) indicating substantially overlapping variance.

Conclusions: PAR and MEP, as defined in our study, can be used to make prognostic judgements regarding risk of poor postoperative outcome trajectory following knee arthroplasty. However, PAR and MEP showed substantially overlapping variance indicating that measurements of both are not necessary when making prognostic assessments.

Significance statement: Preoperative PAR and MEP latent variables, as defined in our study, had prognostic significance for 1 year pain and function outcome trajectories. PAR and MEP latent variables had substantially overlapping variance which suggested that only one is needed to make prognostic judgements. The prognostic significance of PAR and MEP as well as their substantially overlapping variance is new to the field prognostic research in knee arthroplasty.

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来源期刊
European Journal of Pain
European Journal of Pain 医学-临床神经学
CiteScore
7.50
自引率
5.60%
发文量
163
审稿时长
4-8 weeks
期刊介绍: European Journal of Pain (EJP) publishes clinical and basic science research papers relevant to all aspects of pain and its management, including specialties such as anaesthesia, dentistry, neurology and neurosurgery, orthopaedics, palliative care, pharmacology, physiology, psychiatry, psychology and rehabilitation; socio-economic aspects of pain are also covered. Regular sections in the journal are as follows: • Editorials and Commentaries • Position Papers and Guidelines • Reviews • Original Articles • Letters • Bookshelf The journal particularly welcomes clinical trials, which are published on an occasional basis. Research articles are published under the following subject headings: • Neurobiology • Neurology • Experimental Pharmacology • Clinical Pharmacology • Psychology • Behavioural Therapy • Epidemiology • Cancer Pain • Acute Pain • Clinical Trials.
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