阿片类药物处方限制与无家可归问题:从氢可酮重新列表中获得的证据

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Johabed G. Olvera , Felipe Lozano-Rojas , Julio A. Ramos Pastrana , Sumedha Gupta
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引用次数: 0

摘要

本文研究了限制阿片类药物处方对无家可归者的影响。我们通过利用阿片类药物限制政策(即氢可酮(即维柯丁,而非奥施康定等羟考酮产品)重新列表)所导致的阿片类药物处方供应的合理外生变化来评估这种关系。氢可酮是美国处方量最大的阿片类药物,占阿片类药物处方配药总量的 55%,我们通过比较政策颁布前后氢可酮暴露量较高地区与暴露量较低地区的无家可归者人数,确定了氢可酮供应量减少的因果效应。我们发现,在氢可酮纳入管制范围后的一个季度,每 10 万居民中的无家可归者人数减少了近 56 人(与政策颁布前的平均值相比减少了 25.4%)。此外,结果还显示,氢可酮处方、与毒品相关的死亡、失业和离婚率在调高管制后都有所下降。综上所述,我们的研究结果表明,在我们的研究期间(2007-2017 年),氢可酮的重新安排避免了一些家庭危机,从而减少了无家可归者的数量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Opioids prescribing restrictions and homelessness: Evidence from hydrocodone rescheduling

This paper examines the effect of restricting opioid prescription on homelessness. We assess this relationship by exploiting plausible exogenous variation in prescribed opioid supply derived from an opioid restriction policy: the hydrocodone (i.e., Vicodin, not oxycodone products like Oxycontin) rescheduling. We identified the causal effect of this decrease in the supply of hydrocodone, the most prescribed opioid in the U.S. and comprising 55% of overall use opioid prescription dispensing, by comparing the number of homeless individuals in geographies with higher exposure to Hydrocodone against those in areas with lower exposure, before and after the enactment of the policy. We find that in the quarter following hydrocodone upscheduling, the rate of people experiencing homelessness decreased by almost 56 per 100,000 inhabitants (a 25.4% reduction relative to the pre-policy mean). In addition, results show that hydrocodone prescriptions, drug related deaths, unemployment, and divorce rates decrease following the upscheduling. Taken together, our results suggest that during our study period (2007–2017) the hydrocodone rescheduling reduced homelessness by preventing some household crises.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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