{"title":"咪唑的绿色合成:磁性纳米颗粒的催化功效","authors":"Vaishali , Shubham Sharma , Kanchna Bhatrola , Ali Irfan , Nisha Devi , Kaushiki Mishra , Khushali Dubey , Ankit Mittal , Emilio Mateev , Vinod Kumar Vashistha","doi":"10.1016/j.tet.2024.134246","DOIUrl":null,"url":null,"abstract":"<div><p>In the present scenario, environment-friendly reactions in organic synthesis have a unique and irreplaceable place. In the past, there are significant progress in the development of more nature-friendly and sustainable methods for various organic transformations. The nature-friendly and sustainable methods make a tool named green synthesis which utilizes for the synthesis of various drug candidates. Within perspectives of green synthesis, the magnetic nanoparticles attract considerable attention due to its many characteristics and utilization in the green synthesis. In organic synthesis, magnetic nanoparticles have been used as a green catalyst for the formation of various heterocycles. In the realm of organic compounds, imidazole is considered a preferred and highly valuable motif among aza-heterocycles. It presents a favourable opportunity for discovering lead structures in the quest for new synthetic molecules with potential therapeutic properties and other significant prospects. The synthesis of imidazole due to its exciting profile is very much demanding by using magnetic nanoparticles as a green catalyst. Accordingly, the pure and functionalized magnetic nanoparticles display significant potential in the synthesis of a diverse range of imidazole derivatives. Therefore, this manuscript compiles the current research (from 2004 to present) on the role of environmentally safe pure and functionalized magnetic nanoparticles for generating a wide variety of valuable imidazoles.</p></div>","PeriodicalId":437,"journal":{"name":"Tetrahedron","volume":"167 ","pages":"Article 134246"},"PeriodicalIF":2.1000,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Green synthesis of imidazoles: The catalytic efficacy of magnetic nanoparticles\",\"authors\":\"Vaishali , Shubham Sharma , Kanchna Bhatrola , Ali Irfan , Nisha Devi , Kaushiki Mishra , Khushali Dubey , Ankit Mittal , Emilio Mateev , Vinod Kumar Vashistha\",\"doi\":\"10.1016/j.tet.2024.134246\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In the present scenario, environment-friendly reactions in organic synthesis have a unique and irreplaceable place. In the past, there are significant progress in the development of more nature-friendly and sustainable methods for various organic transformations. The nature-friendly and sustainable methods make a tool named green synthesis which utilizes for the synthesis of various drug candidates. Within perspectives of green synthesis, the magnetic nanoparticles attract considerable attention due to its many characteristics and utilization in the green synthesis. In organic synthesis, magnetic nanoparticles have been used as a green catalyst for the formation of various heterocycles. In the realm of organic compounds, imidazole is considered a preferred and highly valuable motif among aza-heterocycles. It presents a favourable opportunity for discovering lead structures in the quest for new synthetic molecules with potential therapeutic properties and other significant prospects. The synthesis of imidazole due to its exciting profile is very much demanding by using magnetic nanoparticles as a green catalyst. Accordingly, the pure and functionalized magnetic nanoparticles display significant potential in the synthesis of a diverse range of imidazole derivatives. Therefore, this manuscript compiles the current research (from 2004 to present) on the role of environmentally safe pure and functionalized magnetic nanoparticles for generating a wide variety of valuable imidazoles.</p></div>\",\"PeriodicalId\":437,\"journal\":{\"name\":\"Tetrahedron\",\"volume\":\"167 \",\"pages\":\"Article 134246\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-09-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tetrahedron\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0040402024004265\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0040402024004265","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Green synthesis of imidazoles: The catalytic efficacy of magnetic nanoparticles
In the present scenario, environment-friendly reactions in organic synthesis have a unique and irreplaceable place. In the past, there are significant progress in the development of more nature-friendly and sustainable methods for various organic transformations. The nature-friendly and sustainable methods make a tool named green synthesis which utilizes for the synthesis of various drug candidates. Within perspectives of green synthesis, the magnetic nanoparticles attract considerable attention due to its many characteristics and utilization in the green synthesis. In organic synthesis, magnetic nanoparticles have been used as a green catalyst for the formation of various heterocycles. In the realm of organic compounds, imidazole is considered a preferred and highly valuable motif among aza-heterocycles. It presents a favourable opportunity for discovering lead structures in the quest for new synthetic molecules with potential therapeutic properties and other significant prospects. The synthesis of imidazole due to its exciting profile is very much demanding by using magnetic nanoparticles as a green catalyst. Accordingly, the pure and functionalized magnetic nanoparticles display significant potential in the synthesis of a diverse range of imidazole derivatives. Therefore, this manuscript compiles the current research (from 2004 to present) on the role of environmentally safe pure and functionalized magnetic nanoparticles for generating a wide variety of valuable imidazoles.
期刊介绍:
Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry.
Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters.
Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.