鼠疫疫苗研发进展情况及行动呼吁。

IF 6.9 1区医学 Q1 IMMUNOLOGY

NPJ Vaccines Pub Date : 2024-09-07 DOI:10.1038/s41541-024-00958-1

E Diane Williamson, Paul B Kilgore, Emily K Hendrix, Blake H Neil, Jian Sha, Ashok K Chopra

{"title":"鼠疫疫苗研发进展情况及行动呼吁。","authors":"E Diane Williamson, Paul B Kilgore, Emily K Hendrix, Blake H Neil, Jian Sha, Ashok K Chopra","doi":"10.1038/s41541-024-00958-1","DOIUrl":null,"url":null,"abstract":"There is a compelling demand for approved plague vaccines due to the endemicity of Yersinia pestis and its potential for pandemic spread. Whilst substantial progress has been made, we recommend that the global funding and health security systems should work urgently to translate some of the efficacious vaccines reviewed herein to expedite clinical development and to prevent future disastrous plague outbreaks, particularly caused by antimicrobial resistant Y. pestis strains.Content includes material subject to Crown Copyright © 2024.This is an open access article under the Open Government License ( http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/ ).","PeriodicalId":19335,"journal":{"name":"NPJ Vaccines","volume":null,"pages":null},"PeriodicalIF":6.9000,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379892/pdf/","citationCount":"0","resultStr":"{\"title\":\"Progress on the research and development of plague vaccines with a call to action.\",\"authors\":\"E Diane Williamson, Paul B Kilgore, Emily K Hendrix, Blake H Neil, Jian Sha, Ashok K Chopra\",\"doi\":\"10.1038/s41541-024-00958-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"There is a compelling demand for approved plague vaccines due to the endemicity of Yersinia pestis and its potential for pandemic spread. Whilst substantial progress has been made, we recommend that the global funding and health security systems should work urgently to translate some of the efficacious vaccines reviewed herein to expedite clinical development and to prevent future disastrous plague outbreaks, particularly caused by antimicrobial resistant Y. pestis strains.Content includes material subject to Crown Copyright © 2024.This is an open access article under the Open Government License ( http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/ ).\",\"PeriodicalId\":19335,\"journal\":{\"name\":\"NPJ Vaccines\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":6.9000,\"publicationDate\":\"2024-09-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379892/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"NPJ Vaccines\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41541-024-00958-1\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"NPJ Vaccines","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41541-024-00958-1","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

由于鼠疫耶尔森氏菌的地方流行性及其大流行传播的潜力，我们迫切希望获得批准的鼠疫疫苗。虽然已经取得了实质性进展，但我们建议全球资金和健康安全系统应紧急行动起来，将本文中评述的一些有效疫苗转化为临床开发成果，以防止未来灾难性的鼠疫爆发，尤其是由具有抗药性的鼠疫耶尔森菌株引起的鼠疫爆发。内容包括受版权保护的材料© 2024。本文是根据开放政府许可( http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/ ) 发布的开放存取文章。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Progress on the research and development of plague vaccines with a call to action.

查看原文本刊更多论文

Progress on the research and development of plague vaccines with a call to action.

There is a compelling demand for approved plague vaccines due to the endemicity of Yersinia pestis and its potential for pandemic spread. Whilst substantial progress has been made, we recommend that the global funding and health security systems should work urgently to translate some of the efficacious vaccines reviewed herein to expedite clinical development and to prevent future disastrous plague outbreaks, particularly caused by antimicrobial resistant Y. pestis strains.Content includes material subject to Crown Copyright © 2024.This is an open access article under the Open Government License ( http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/ ).

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

NPJ Vaccines Immunology and Microbiology-Immunology

CiteScore

11.90

自引率

4.30%

发文量

146

审稿时长

11 weeks

期刊介绍： Online-only and open access, npj Vaccines is dedicated to highlighting the most important scientific advances in vaccine research and development.