Manuel A Morales, Scott Johnson, Patrick Pierce, Reza Nezafat
{"title":"利用分辨率增强网络加速化学位移编码心脏磁共振成像","authors":"Manuel A Morales, Scott Johnson, Patrick Pierce, Reza Nezafat","doi":"10.1016/j.jocmr.2024.101090","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular magnetic resonance (CMR) chemical shift encoding (CSE) enables myocardial fat imaging. We sought to develop a deep learning network (fast chemical shift encoding [FastCSE]) to accelerate CSE.</p><p><strong>Methods: </strong>FastCSE was built on a super-resolution generative adversarial network extended to enhance complex-valued image sharpness. FastCSE enhances each echo image independently before water-fat separation. FastCSE was trained with retrospectively identified cines from 1519 patients (56 ± 16 years; 866 men) referred for clinical 3T CMR. In a prospective study of 16 participants (58 ± 19 years; 7 females) and 5 healthy individuals (32 ± 17 years; 5 females), dual-echo CSE images were collected with 1.5 × 1.5 mm<sup>2</sup>, 2.5 × 1.5 mm<sup>2</sup>, and 3.8 × 1.9 mm<sup>2</sup> resolution using generalized autocalibrating partially parallel acquisition (GRAPPA). FastCSE was applied to images collected with resolution of 2.5 × 1.5 mm<sup>2</sup> and 3.8 × 1.9 mm<sup>2</sup> to restore sharpness. Fat images obtained from two-point Dixon reconstruction were evaluated using a quantitative blur metric and analyzed with a five-way analysis of variance.</p><p><strong>Results: </strong>FastCSE successfully reconstructed CSE images inline. FastCSE acquisition, with a resolution of 2.5 × 1.5 mm<sup>2</sup> and 3.8 × 1.9 mm<sup>2</sup>, reduced the number of breath-holds without impacting visualization of fat by approximately 1.5-fold and 3-fold compared to GRAPPA acquisition with a resolution of 1.5 × 1.5 mm<sup>2</sup>, from 3.0 ± 0.8 breath-holds to 2.0 ± 0.2 and 1.1 ± 0.4 breath-holds, respectively. FastCSE improved image sharpness and removed ringing artifacts in GRAPPA fat images acquired with a resolution of 2.5 × 1.5 mm<sup>2</sup> (0.32 ± 0.03 vs 0.35 ± 0.04, P < 0.001) and 3.8 × 1.9 mm<sup>2</sup> (0.32 ± 0.03 vs 0.43 ± 0.06, P < 0.001). Blurring in FastCSE images was similar to blurring in images with 1.5 × 1.5 mm<sup>2</sup> resolution (0.32 ± 0.03 vs 0.31 ± 0.03, P = 0.57; 0.32 ± 0.03 vs 0.31 ± 0.03, P = 0.66).</p><p><strong>Conclusion: </strong>We showed that a deep learning-accelerated CSE technique based on complex-valued resolution enhancement can reduce the number of breath-holds in CSE imaging without impacting the visualization of fat. FastCSE showed similar image sharpness compared to a standardized parallel imaging method.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101090"},"PeriodicalIF":4.2000,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Accelerated chemical shift encoded cardiovascular magnetic resonance imaging with use of a resolution enhancement network.\",\"authors\":\"Manuel A Morales, Scott Johnson, Patrick Pierce, Reza Nezafat\",\"doi\":\"10.1016/j.jocmr.2024.101090\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Cardiovascular magnetic resonance (CMR) chemical shift encoding (CSE) enables myocardial fat imaging. We sought to develop a deep learning network (fast chemical shift encoding [FastCSE]) to accelerate CSE.</p><p><strong>Methods: </strong>FastCSE was built on a super-resolution generative adversarial network extended to enhance complex-valued image sharpness. FastCSE enhances each echo image independently before water-fat separation. FastCSE was trained with retrospectively identified cines from 1519 patients (56 ± 16 years; 866 men) referred for clinical 3T CMR. In a prospective study of 16 participants (58 ± 19 years; 7 females) and 5 healthy individuals (32 ± 17 years; 5 females), dual-echo CSE images were collected with 1.5 × 1.5 mm<sup>2</sup>, 2.5 × 1.5 mm<sup>2</sup>, and 3.8 × 1.9 mm<sup>2</sup> resolution using generalized autocalibrating partially parallel acquisition (GRAPPA). FastCSE was applied to images collected with resolution of 2.5 × 1.5 mm<sup>2</sup> and 3.8 × 1.9 mm<sup>2</sup> to restore sharpness. Fat images obtained from two-point Dixon reconstruction were evaluated using a quantitative blur metric and analyzed with a five-way analysis of variance.</p><p><strong>Results: </strong>FastCSE successfully reconstructed CSE images inline. FastCSE acquisition, with a resolution of 2.5 × 1.5 mm<sup>2</sup> and 3.8 × 1.9 mm<sup>2</sup>, reduced the number of breath-holds without impacting visualization of fat by approximately 1.5-fold and 3-fold compared to GRAPPA acquisition with a resolution of 1.5 × 1.5 mm<sup>2</sup>, from 3.0 ± 0.8 breath-holds to 2.0 ± 0.2 and 1.1 ± 0.4 breath-holds, respectively. FastCSE improved image sharpness and removed ringing artifacts in GRAPPA fat images acquired with a resolution of 2.5 × 1.5 mm<sup>2</sup> (0.32 ± 0.03 vs 0.35 ± 0.04, P < 0.001) and 3.8 × 1.9 mm<sup>2</sup> (0.32 ± 0.03 vs 0.43 ± 0.06, P < 0.001). Blurring in FastCSE images was similar to blurring in images with 1.5 × 1.5 mm<sup>2</sup> resolution (0.32 ± 0.03 vs 0.31 ± 0.03, P = 0.57; 0.32 ± 0.03 vs 0.31 ± 0.03, P = 0.66).</p><p><strong>Conclusion: </strong>We showed that a deep learning-accelerated CSE technique based on complex-valued resolution enhancement can reduce the number of breath-holds in CSE imaging without impacting the visualization of fat. FastCSE showed similar image sharpness compared to a standardized parallel imaging method.</p>\",\"PeriodicalId\":15221,\"journal\":{\"name\":\"Journal of Cardiovascular Magnetic Resonance\",\"volume\":\" \",\"pages\":\"101090\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2024-09-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cardiovascular Magnetic Resonance\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jocmr.2024.101090\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cardiovascular Magnetic Resonance","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1016/j.jocmr.2024.101090","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Accelerated chemical shift encoded cardiovascular magnetic resonance imaging with use of a resolution enhancement network.
Background: Cardiovascular magnetic resonance (CMR) chemical shift encoding (CSE) enables myocardial fat imaging. We sought to develop a deep learning network (fast chemical shift encoding [FastCSE]) to accelerate CSE.
Methods: FastCSE was built on a super-resolution generative adversarial network extended to enhance complex-valued image sharpness. FastCSE enhances each echo image independently before water-fat separation. FastCSE was trained with retrospectively identified cines from 1519 patients (56 ± 16 years; 866 men) referred for clinical 3T CMR. In a prospective study of 16 participants (58 ± 19 years; 7 females) and 5 healthy individuals (32 ± 17 years; 5 females), dual-echo CSE images were collected with 1.5 × 1.5 mm2, 2.5 × 1.5 mm2, and 3.8 × 1.9 mm2 resolution using generalized autocalibrating partially parallel acquisition (GRAPPA). FastCSE was applied to images collected with resolution of 2.5 × 1.5 mm2 and 3.8 × 1.9 mm2 to restore sharpness. Fat images obtained from two-point Dixon reconstruction were evaluated using a quantitative blur metric and analyzed with a five-way analysis of variance.
Results: FastCSE successfully reconstructed CSE images inline. FastCSE acquisition, with a resolution of 2.5 × 1.5 mm2 and 3.8 × 1.9 mm2, reduced the number of breath-holds without impacting visualization of fat by approximately 1.5-fold and 3-fold compared to GRAPPA acquisition with a resolution of 1.5 × 1.5 mm2, from 3.0 ± 0.8 breath-holds to 2.0 ± 0.2 and 1.1 ± 0.4 breath-holds, respectively. FastCSE improved image sharpness and removed ringing artifacts in GRAPPA fat images acquired with a resolution of 2.5 × 1.5 mm2 (0.32 ± 0.03 vs 0.35 ± 0.04, P < 0.001) and 3.8 × 1.9 mm2 (0.32 ± 0.03 vs 0.43 ± 0.06, P < 0.001). Blurring in FastCSE images was similar to blurring in images with 1.5 × 1.5 mm2 resolution (0.32 ± 0.03 vs 0.31 ± 0.03, P = 0.57; 0.32 ± 0.03 vs 0.31 ± 0.03, P = 0.66).
Conclusion: We showed that a deep learning-accelerated CSE technique based on complex-valued resolution enhancement can reduce the number of breath-holds in CSE imaging without impacting the visualization of fat. FastCSE showed similar image sharpness compared to a standardized parallel imaging method.
期刊介绍：
Journal of Cardiovascular Magnetic Resonance (JCMR) publishes high-quality articles on all aspects of basic, translational and clinical research on the design, development, manufacture, and evaluation of cardiovascular magnetic resonance (CMR) methods applied to the cardiovascular system. Topical areas include, but are not limited to:
New applications of magnetic resonance to improve the diagnostic strategies, risk stratification, characterization and management of diseases affecting the cardiovascular system.
New methods to enhance or accelerate image acquisition and data analysis.
Results of multicenter, or larger single-center studies that provide insight into the utility of CMR.
Basic biological perceptions derived by CMR methods.
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