对急性冠状动脉综合征和多血管疾病患者进行长病变支架植入术对临床疗效的影响:来自 BIOVASC 试验的数据。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Hala Kakar MD , Jacob J. Elscot BSc , Annebel de Gier BSc , Wijnand K. Den Dekker MD, PhD , Johan Bennett MD, PhD , Manel Sabaté MD, PhD , Giovanni Esposito MD, PhD , Eric Boersma MD, PhD , Nicolas M. Van Mieghem MD, PhD , Roberto Diletti MD, PhD , BIOVASC investigators
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引用次数: 0

摘要

支架总长度(TSL)的增加可能与较高的临床事件风险有关,但对于多血管疾病(MVD)患者来说,往往需要相当长的支架总长度。在 BIOVASC 试验中,对于急性冠状动脉综合征(ACS)和 MVD 患者,立即完全血运重建与较短的 TSL 有关。本文是 BIOVASC 试验的一项子分析,比较了急性冠状动脉综合征和 MVD 患者的临床结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of Stenting Long Lesions on Clinical Outcomes in Patients Presenting With Acute Coronary Syndrome and Multivessel Disease: Data From the BIOVASC Trial
An increased total stent length (TSL) might be associated with a higher risk of clinical events; however, in patients with multivessel disease (MVD), a considerable TSL is often required. In patients presenting with acute coronary syndrome and MVD, immediate complete revascularization was associated with shorter TSL in the BIOVASC (Immediate versus staged complete revascularisation in patients presenting with acute coronary syndrome and multivessel coronary disease) Trial. This is a subanalysis of the BIOVASC trial comparing clinical outcomes in patients with either <60 or ≥60 mm TSL. The primary outcome was a composite of all-cause mortality, myocardial infarction, any unplanned ischemia driven revascularization, or cerebrovascular events at 2 years after the index procedure. A total of 1,525 patients were enrolled in the BIOVASC trial, of whom 855 had a TSL of ≥60 mm (long TSL). No significant difference was established when comparing patients treated with either long or short TSL in terms of the primary outcome at 2-year follow-up, which occurred in 117 patients (13.7%) in the ≥60 mm group and 69 patients (10.3%) in the <60 mm group (adjusted hazard ratio 1.25, 95% confidence interval 0.92 to 1.69, p = 0.16). Furthermore, no significant differences were observed in the secondary end points. In conclusion, in patients with acute coronary syndrome and MVD, long stenting did not show a significant difference in clinical event rate compared with short stenting.
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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