老年人癌症发病率不断上升:流行病学趋势调查。

IF 2.2 Q3 GERIATRICS & GERONTOLOGY
Aging Medicine Pub Date : 2024-08-18 DOI:10.1002/agm2.12347
Ramya Prathap, Sherlin Kirubha, Aravindhan Thiyaga Rajan, Santhosh Manoharan, Karthikeyan Elumalai
{"title":"老年人癌症发病率不断上升:流行病学趋势调查。","authors":"Ramya Prathap,&nbsp;Sherlin Kirubha,&nbsp;Aravindhan Thiyaga Rajan,&nbsp;Santhosh Manoharan,&nbsp;Karthikeyan Elumalai","doi":"10.1002/agm2.12347","DOIUrl":null,"url":null,"abstract":"<p>Cancer poses a significant health threat to the elderly, accounting for a substantial proportion of cancer patients aged 65 and above. As life expectancy continues to rise and the population ages, the incidence of cancer in the elderly is expected to increase further. Age is a major risk factor for the majority of common cancers, with the incidence and prevalence rising as individuals grow older. Factors such as chemoprevention and environmental carcinogen elimination may influence the process of carcinogenesis. Studies reveal that the incidence and mortality rates of various cancers in the elderly and extremely old individuals are on the rise worldwide, with most types peaking around the age of 75 to 90, followed by a sharp decline. Birth cohort and period effects also play a complex role in the connection between aging and cancer risk. Clinical trials often exclude older individuals, limiting our understanding of cancer treatments' effects on this particular age group. More research is needed to focus on the unique requirements of older adults with cancer.</p>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":"7 4","pages":"516-527"},"PeriodicalIF":2.2000,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11369332/pdf/","citationCount":"0","resultStr":"{\"title\":\"The increasing prevalence of cancer in the elderly: An investigation of epidemiological trends\",\"authors\":\"Ramya Prathap,&nbsp;Sherlin Kirubha,&nbsp;Aravindhan Thiyaga Rajan,&nbsp;Santhosh Manoharan,&nbsp;Karthikeyan Elumalai\",\"doi\":\"10.1002/agm2.12347\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Cancer poses a significant health threat to the elderly, accounting for a substantial proportion of cancer patients aged 65 and above. As life expectancy continues to rise and the population ages, the incidence of cancer in the elderly is expected to increase further. Age is a major risk factor for the majority of common cancers, with the incidence and prevalence rising as individuals grow older. Factors such as chemoprevention and environmental carcinogen elimination may influence the process of carcinogenesis. Studies reveal that the incidence and mortality rates of various cancers in the elderly and extremely old individuals are on the rise worldwide, with most types peaking around the age of 75 to 90, followed by a sharp decline. Birth cohort and period effects also play a complex role in the connection between aging and cancer risk. Clinical trials often exclude older individuals, limiting our understanding of cancer treatments' effects on this particular age group. More research is needed to focus on the unique requirements of older adults with cancer.</p>\",\"PeriodicalId\":32862,\"journal\":{\"name\":\"Aging Medicine\",\"volume\":\"7 4\",\"pages\":\"516-527\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2024-08-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11369332/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Aging Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/agm2.12347\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"GERIATRICS & GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aging Medicine","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/agm2.12347","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

癌症对老年人的健康构成重大威胁,在 65 岁及以上的癌症患者中占很大比例。随着预期寿命的不断延长和人口的老龄化,预计老年人的癌症发病率将进一步上升。年龄是大多数常见癌症的主要风险因素,随着年龄的增长,癌症的发病率和流行率也在上升。化学预防和消除环境致癌物等因素可能会影响致癌过程。研究显示,全球老年人和高龄老人的各种癌症发病率和死亡率呈上升趋势,大多数类型的癌症在 75 至 90 岁左右达到峰值,随后急剧下降。出生组群和时期效应在老龄化与癌症风险之间也起着复杂的作用。临床试验通常将老年人排除在外,这限制了我们对癌症治疗对这一特殊年龄组的影响的了解。我们需要开展更多的研究来关注老年癌症患者的独特需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The increasing prevalence of cancer in the elderly: An investigation of epidemiological trends

The increasing prevalence of cancer in the elderly: An investigation of epidemiological trends

Cancer poses a significant health threat to the elderly, accounting for a substantial proportion of cancer patients aged 65 and above. As life expectancy continues to rise and the population ages, the incidence of cancer in the elderly is expected to increase further. Age is a major risk factor for the majority of common cancers, with the incidence and prevalence rising as individuals grow older. Factors such as chemoprevention and environmental carcinogen elimination may influence the process of carcinogenesis. Studies reveal that the incidence and mortality rates of various cancers in the elderly and extremely old individuals are on the rise worldwide, with most types peaking around the age of 75 to 90, followed by a sharp decline. Birth cohort and period effects also play a complex role in the connection between aging and cancer risk. Clinical trials often exclude older individuals, limiting our understanding of cancer treatments' effects on this particular age group. More research is needed to focus on the unique requirements of older adults with cancer.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Aging Medicine
Aging Medicine Medicine-Geriatrics and Gerontology
CiteScore
4.10
自引率
0.00%
发文量
38
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信