评估术中利多卡因对妇科腹腔镜手术术后肩痛的预防作用:前瞻性随机、双盲、安慰剂对照研究。

IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY
Liyan Zhao, Bin Li, Ningkang Li, Jiamin Bao, Xiaoning Zhu, Kerong Hai
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引用次数: 0

摘要

目的:评估术中利多卡因对降低妇科腹腔镜手术后肩痛(PLSP)发生率的有效性:方法:将接受全腹腔镜子宫切除术的患者随机分为两组:利多卡因组和安慰剂组,利多卡因组在麻醉诱导前静脉注射初始剂量的利多卡因(1.5 mg/kg),然后以2 mg/kg/h的剂量持续输注;安慰剂组则使用生理盐水。主要终点是确定手术后72小时内PLSP的发生率。次要终点包括对术后72小时内肩部、腹部和切口疼痛的疼痛强度进行综合评估,评估采用数字评分量表(NRS)。此外,终点还包括评估洛芬考定或帕瑞昔布钠的使用频率、恶心和呕吐的发生率、麻醉和手术过程的持续时间以及住院时间:我们的研究结果表明,在术后期间,PLSP 的发生率并没有明显降低。利多卡因组的 41 位患者中有 14 位(34.1%)发生了 PLSP,而安慰剂组的 41 位患者中有 15 位(36.6%)发生了 PLSP(P = 0.817)。静脉注射利多卡因降低了腹痛评分,减少了术后 72 小时内对术后镇痛药的需求。在切口和肩部疼痛强度、恶心和呕吐率以及住院时间方面,各组之间没有发现明显差异:结论:输注利多卡因并不能降低腹腔镜全子宫切除术患者PLSP的发生率或严重程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of intraoperative lidocaine on the prevention of postoperative shoulder pain in gynecologic laparoscopy: A prospective randomized, double-blind, placebo-controlled study

Aim

To assess the effectiveness of intraoperative lidocaine in reducing the incidence of post-laparoscopic shoulder pain (PLSP) after gynecologic laparoscopy.

Methods

Patients undergoing total laparoscopic hysterectomy were randomly divided into two groups: the lidocaine group, receiving an initial intravenous dose of lidocaine (1.5 mg/kg) before anesthesia induction, followed by a continuous infusion at 2 mg/kg/h, and the placebo group, receiving saline. The primary endpoint was the determination of PLSP incidence over a 72-h period post-surgery. Secondary endpoints included a comprehensive evaluation of pain intensity, as measured by the Numeric Rating Scale (NRS), for shoulder, abdominal, and incisional pain within a 72-hour period postoperatively. Additionally, the endpoints involved the assessment of Lofencodeine or Parexib Sodium usage frequency, incidence of nausea and vomiting, duration of anesthesia and surgical procedure, as well as the duration of hospital stay.

Results

Our study did not demonstrate any significant benefit in the incidence of PLSP during the postoperative period. PLSP occurred in 14 out of 41 patients (34.1%) in the lidocaine group, compared with 15 out of 41 patients (36.6%) in the placebo group (p = 0.817). Intravenous lidocaine reduced abdominal pain scores and decreased the need for postoperative analgesics within 72 h after surgery. No significant differences were found in incisional and shoulder pain intensity, nausea and vomiting rates, or hospitalization duration between groups.

Conclusions

The infusion of lidocaine did not yield a reduction in the incidence or severity of PLSP in patients undergoing laparoscopic total hysterectomy.

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来源期刊
CiteScore
3.10
自引率
0.00%
发文量
376
审稿时长
3-6 weeks
期刊介绍: The Journal of Obstetrics and Gynaecology Research is the official Journal of the Asia and Oceania Federation of Obstetrics and Gynecology and of the Japan Society of Obstetrics and Gynecology, and aims to provide a medium for the publication of articles in the fields of obstetrics and gynecology. The Journal publishes original research articles, case reports, review articles and letters to the editor. The Journal will give publication priority to original research articles over case reports. Accepted papers become the exclusive licence of the Journal. Manuscripts are peer reviewed by at least two referees and/or Associate Editors expert in the field of the submitted paper.
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