68Ga-FAPI PET/CT 显示缺血性结肠炎的纤维化情况

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2024-09-02 DOI:10.1097/RLU.0000000000005430

Jieling Zheng, Qian Ru, Yun Yang, Weibing Miao

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引用次数: 0

摘要

摘要：缺血性结肠炎是缺血性肠病中最常见的一种，但用 PET/CT 鉴定缺血性结肠炎却很少见。我们报告了一例原因不明的缺血性结肠炎病例，患者为排除肠道恶性肿瘤而接受了 18F-FDG PET/CT，随后被招募参加 68Ga-FAPI 临床试验。18F-FDG PET/CT 显示，肠腔内有慢性炎症的粘膜具有很强的活性。相反，68Ga-FAPI PET/CT 则显示肠壁和邻近肠系膜的示踪剂摄取量较高。我们的病例显示了 18F-FDG 和 68Ga-FAPI 在缺血性结肠炎中的不同分布模式。

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68 Ga-FAPI PET/CT Depicted the Fibrosis of Ischemic Colitis.

Abstract: Ischemic colitis is the most common form of ischemic bowel disease; identification of ischemic colitis with PET/CT is rare. We present a case of unexplained ischemic colitis in a 66-year-old man who underwent 18 F-FDG PET/CT to exclude intestinal malignancy and was subsequently recruited in a clinical trial regarding 68 Ga-FAPI. 18 F-FDG PET/CT showed intense activity in the intestinal lumen where mucosa had chronic inflammation. Conversely, 68 Ga-FAPI PET/CT revealed high tracer uptake in the intestinal wall and adjacent mesentery. Our case showed the different distribution pattern of 18 F-FDG and 68 Ga-FAPI in ischemic colitis.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.