{"title":"EWGSOP2 和 SDOC 对 \"肌肉疏松症 \"的定义能否识别功能性肌肉质量？","authors":"Patricia Parreira Batista, Monica Rodrigues Perracini, Daniele Sirineu Pereira, Juleimar Soares Coelho De Amorim, Leani Souza Máximo Pereira","doi":"10.22540/JFSF-09-192","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To compare the European Working Group on Sarcopenia in Older People (EWGSOP2) and the Sarcopenia Definition and Outcomes Consortium (SDOC) in identifying muscle quality indexes (MQI) and lower limb muscle performance in older women aged ≥ 65.</p><p><strong>Methods: </strong>Participants meeting EWGSOP2 and SDOC criteria were classified into the sarcopenia group (GS); others were placed in the non-sarcopenia group (GNS). Using an isokinetic dynamometer, we assessed peak torque (PT), maximal work (MW), and power (POW) of lower limbs. MQI was calculated as the ratio of muscle performance to appendicular lean mass, adjusted for body mass index (BMI) and lean tissue mass of the right lower limb (LTM).</p><p><strong>Results: </strong>We included 96 older women. In both SDOC (n=37) and EWGSOP2 (n=48) sarcopenia groups, muscle performance and BMI-adjusted MQI were significantly lower. Sarcopenia (SDOC) was significantly associated with all lower limb muscle performance and MQI variables [adjusted model by age and race: MQI<sub>POW/LTM</sub> OR = 0.67 (95% CI 0.52; 0.85); MQI<sub>PT/LTM</sub> OR = 0.76 (95% CI 0.64; 0.89)].</p><p><strong>Conclusions: </strong>Older women diagnosed with sarcopenia by EWGSOP2 and SDOC criteria showed significant declines in muscle function and quality. The SDOC definition discriminated muscle contraction quality components in older individuals with and without sarcopenia.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"192-200"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367082/pdf/","citationCount":"0","resultStr":"{\"title\":\"Can EWGSOP2 and SDOC Definitions of Sarcopenia Identify Functional Muscle Quality?\",\"authors\":\"Patricia Parreira Batista, Monica Rodrigues Perracini, Daniele Sirineu Pereira, Juleimar Soares Coelho De Amorim, Leani Souza Máximo Pereira\",\"doi\":\"10.22540/JFSF-09-192\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To compare the European Working Group on Sarcopenia in Older People (EWGSOP2) and the Sarcopenia Definition and Outcomes Consortium (SDOC) in identifying muscle quality indexes (MQI) and lower limb muscle performance in older women aged ≥ 65.</p><p><strong>Methods: </strong>Participants meeting EWGSOP2 and SDOC criteria were classified into the sarcopenia group (GS); others were placed in the non-sarcopenia group (GNS). Using an isokinetic dynamometer, we assessed peak torque (PT), maximal work (MW), and power (POW) of lower limbs. MQI was calculated as the ratio of muscle performance to appendicular lean mass, adjusted for body mass index (BMI) and lean tissue mass of the right lower limb (LTM).</p><p><strong>Results: </strong>We included 96 older women. In both SDOC (n=37) and EWGSOP2 (n=48) sarcopenia groups, muscle performance and BMI-adjusted MQI were significantly lower. Sarcopenia (SDOC) was significantly associated with all lower limb muscle performance and MQI variables [adjusted model by age and race: MQI<sub>POW/LTM</sub> OR = 0.67 (95% CI 0.52; 0.85); MQI<sub>PT/LTM</sub> OR = 0.76 (95% CI 0.64; 0.89)].</p><p><strong>Conclusions: </strong>Older women diagnosed with sarcopenia by EWGSOP2 and SDOC criteria showed significant declines in muscle function and quality. The SDOC definition discriminated muscle contraction quality components in older individuals with and without sarcopenia.</p>\",\"PeriodicalId\":73754,\"journal\":{\"name\":\"Journal of frailty, sarcopenia and falls\",\"volume\":\"9 3\",\"pages\":\"192-200\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367082/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of frailty, sarcopenia and falls\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22540/JFSF-09-192\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of frailty, sarcopenia and falls","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22540/JFSF-09-192","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的比较欧洲老年人肌肉疏松症工作组（EWGSOP2）和肌肉疏松症定义与结果联盟（SDOC）在确定≥65岁老年女性肌肉质量指数（MQI）和下肢肌肉表现方面的差异：符合 EWGSOP2 和 SDOC 标准的参与者被归入肌肉疏松症组（GS）；其他参与者被归入非肌肉疏松症组（GNS）。我们使用等动测力计评估下肢的峰值扭矩（PT）、最大功（MW）和功率（POW）。根据体重指数（BMI）和右下肢瘦肉组织质量（LTM）调整后，计算出肌肉性能与附肢瘦肉质量的比率：我们纳入了 96 名老年妇女。在 SDOC 组（37 人）和 EWGSOP2 组（48 人）中，肌肉性能和经体重指数调整后的 MQI 都明显较低。肌肉疏松症（SDOC）与所有下肢肌肉表现和 MQI 变量都有明显关系[根据年龄和种族调整模型：MQIPOW/LTM OR = 0.67 (95% CI 0.52; 0.85); MQIPT/LTM OR = 0.76 (95% CI 0.64; 0.89)]：结论：根据 EWGSOP2 和 SDOC 标准诊断出患有肌肉疏松症的老年妇女，其肌肉功能和质量均有显著下降。SDOC定义可区分患有和未患有肌肉疏松症的老年人的肌肉收缩质量成分。
Can EWGSOP2 and SDOC Definitions of Sarcopenia Identify Functional Muscle Quality?
Objectives: To compare the European Working Group on Sarcopenia in Older People (EWGSOP2) and the Sarcopenia Definition and Outcomes Consortium (SDOC) in identifying muscle quality indexes (MQI) and lower limb muscle performance in older women aged ≥ 65.
Methods: Participants meeting EWGSOP2 and SDOC criteria were classified into the sarcopenia group (GS); others were placed in the non-sarcopenia group (GNS). Using an isokinetic dynamometer, we assessed peak torque (PT), maximal work (MW), and power (POW) of lower limbs. MQI was calculated as the ratio of muscle performance to appendicular lean mass, adjusted for body mass index (BMI) and lean tissue mass of the right lower limb (LTM).
Results: We included 96 older women. In both SDOC (n=37) and EWGSOP2 (n=48) sarcopenia groups, muscle performance and BMI-adjusted MQI were significantly lower. Sarcopenia (SDOC) was significantly associated with all lower limb muscle performance and MQI variables [adjusted model by age and race: MQIPOW/LTM OR = 0.67 (95% CI 0.52; 0.85); MQIPT/LTM OR = 0.76 (95% CI 0.64; 0.89)].
Conclusions: Older women diagnosed with sarcopenia by EWGSOP2 and SDOC criteria showed significant declines in muscle function and quality. The SDOC definition discriminated muscle contraction quality components in older individuals with and without sarcopenia.
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