广泛的分子检测方法仅能在被蜱虫叮咬的迁徙性红斑活检组织和患者血液中鉴定出波氏杆菌属

IF 4.1 2区医学 Q1 INFECTIOUS DISEASES

One Health Pub Date : 2024-08-30 DOI:10.1016/j.onehlt.2024.100886

Philippe Pérot , Laura Tondeur , Sara Moutailler , Delphine Chrétien , Nicole Corre-Catelin , Muriel Vayssier-Taussat , Marc Eloit , Catherine Chirouze , Céline Cazorla

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引用次数: 0

摘要

在法国进行的这项多中心研究中，我们对 22 名被蜱虫叮咬后出现迁徙性红斑的患者中存在鲍氏包虫病以外的病原体传播这一假设提出了质疑。我们在皮肤活检和血液样本中结合使用了高通量微流控 PCR 和不可知元基因组学方法，结果没有发现除鲍瑞氏菌以外的其他微生物。

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Broad range molecular detection methods identify only Borrelia spp. in erythema migrans biopsies and blood of tick-bitten patients

In this multicenter study conducted in France, we challenged the hypothesis of the transmission of pathogens other than Borrelia spp. in 22 patients developing erythema migrans following a tick bite. Using a combination of high-throughput microfluidic PCRs and agnostic metagenomics on skin biopsies and blood samples, no microorganisms other than Borrelia spp. was found.

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来源期刊

One Health Medicine-Infectious Diseases

CiteScore

8.10

自引率

4.00%

发文量

审稿时长

18 weeks

期刊介绍： One Health - a Gold Open Access journal. The mission of One Health is to provide a platform for rapid communication of high quality scientific knowledge on inter- and intra-species pathogen transmission, bringing together leading experts in virology, bacteriology, parasitology, mycology, vectors and vector-borne diseases, tropical health, veterinary sciences, pathology, immunology, food safety, mathematical modelling, epidemiology, public health research and emergency preparedness. As a Gold Open Access journal, a fee is payable on acceptance of the paper. Please see the Guide for Authors for more information. Submissions to the following categories are welcome: Virology, Bacteriology, Parasitology, Mycology, Vectors and vector-borne diseases, Co-infections and co-morbidities, Disease spatial surveillance, Modelling, Tropical Health, Discovery, Ecosystem Health, Public Health.