生物科学与预防科学相结合的前景与挑战:下一代转化研究的社区参与模式。

IF 3 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Leslie D Leve, Mariano Kanamori, Kathryn L Humphreys, Sara R Jaffee, Robin Nusslock, Veronica Oro, Luke W Hyde
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引用次数: 0

摘要

从二十年前人类基因组测序成功开始,根据个人的生物学特征制定个性化健康干预措施的可能性吸引了研究人员、医疗服务提供者和寻求医疗保健服务的个人的想象力。然而,将个性化医疗方法应用于情绪和行为健康方面,却落后于针对身体健康状况的个性化方法的发展。开发更好的方法,将生物科学与预防科学相结合,以确定具有生物基础的风险和保护机制,然后应用这些知识为情绪和行为健康的预防和干预服务提供信息,这具有潜在的价值。本报告是预防研究学会理事会任命的一个特别工作组的工作成果,该工作组旨在探讨生物科学与预防科学相结合所面临的挑战并提出相关建议。我们介绍了这两种方法结合的科学现状和进展障碍,随后提出了促进生物和预防科学结合的建议策略。这些建议以社区参与式研究方法为基础,目的是在未来的研究中以公平为中心,旨在整合这两个学科,最终改善那些经历过情绪和行为问题或面临这些问题风险的人的福祉。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The Promise and Challenges of Integrating Biological and Prevention Sciences: A Community-Engaged Model for the Next Generation of Translational Research.

The Promise and Challenges of Integrating Biological and Prevention Sciences: A Community-Engaged Model for the Next Generation of Translational Research.

Beginning with the successful sequencing of the human genome two decades ago, the possibility of developing personalized health interventions based on one's biology has captured the imagination of researchers, medical providers, and individuals seeking health care services. However, the application of a personalized medicine approach to emotional and behavioral health has lagged behind the development of personalized approaches for physical health conditions. There is potential value in developing improved methods for integrating biological science with prevention science to identify risk and protective mechanisms that have biological underpinnings, and then applying that knowledge to inform prevention and intervention services for emotional and behavioral health. This report represents the work of a task force appointed by the Board of the Society for Prevention Research to explore challenges and recommendations for the integration of biological and prevention sciences. We present the state of the science and barriers to progress in integrating the two approaches, followed by recommended strategies that would promote the responsible integration of biological and prevention sciences. Recommendations are grounded in Community-Based Participatory Research approaches, with the goal of centering equity in future research aimed at integrating the two disciplines to ultimately improve the well-being of those who have disproportionately experienced or are at risk for experiencing emotional and behavioral problems.

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来源期刊
Prevention Science
Prevention Science PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
6.50
自引率
11.40%
发文量
128
期刊介绍: Prevention Science is the official publication of the Society for Prevention Research. The Journal serves as an interdisciplinary forum designed to disseminate new developments in the theory, research and practice of prevention. Prevention sciences encompassing etiology, epidemiology and intervention are represented through peer-reviewed original research articles on a variety of health and social problems, including but not limited to substance abuse, mental health, HIV/AIDS, violence, accidents, teenage pregnancy, suicide, delinquency, STD''s, obesity, diet/nutrition, exercise, and chronic illness. The journal also publishes literature reviews, theoretical articles, meta-analyses, systematic reviews, brief reports, replication studies, and papers concerning new developments in methodology.
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