Eman E Shaban, Yavuz Yigit, Mohamed Elgassim, Ahmed Shaban, Amira Shaban, Amin Ameen, Mohamed Abdurabu, Hany A Zaki
{"title":"COVID-19 与成人和儿童流感感染的临床评估和风险分层比较:全面系统回顾与元分析》。","authors":"Eman E Shaban, Yavuz Yigit, Mohamed Elgassim, Ahmed Shaban, Amira Shaban, Amin Ameen, Mohamed Abdurabu, Hany A Zaki","doi":"10.30476/BEAT.2024.102205.1504","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare the clinical risks and outcomes of COVID-19 and influenza.</p><p><strong>Methods: </strong>The search for relevant articles was conducted using both a database search method and a manual search, which involved searching through the reference lists of articles related to the topic for additional studies. The Quality assessment was carried out using the Newcastle Ottawa tool, and the data analysis was conducted using the Review Manager Software (RevMan 5.4.1).</p><p><strong>Results: </strong>The meta-analysis results indicated that COVID-19 patients had similar lengths of hospital stays (SMD: -0.25; 95% CI: -0.60-0.11; <i>p</i>=0.17). However, COVID-19 patients had significantly higher mortality rates (RR: 0.28; 95% CI: 0.21-0.37; <i>p</i><0.0001), in-hospital complications (RR: 0.57; 95% CI: 0.50-0.65; <i>p</i><0.00001), intensive care unit (ICU) admissions (OR: 0.48; 95% CI: 0.37-0.61; <i>p</i><0.00001), length of ICU stay (SMD: -0.45; 95% CI: -0.83-0.06; <i>p</i>=0.02), and mechanical ventilation use (OR: 0.36; 95% CI: 0.28-0.46; <i>p</i><0.00001).</p><p><strong>Conclusion: </strong>The findings suggested that COVID-19 was more severe than influenza. Therefore, \"flu-like\" symptoms should not be dismissed without a clear diagnosis, especially during the winter when influenza is more prevalent.</p>","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"12 2","pages":"47-57"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366268/pdf/","citationCount":"0","resultStr":"{\"title\":\"Comparative Clinical Assessment and Risk Stratification of COVID-19 and Influenza Infections in Adults and Children: A Comprehensive Systematic Review and Meta-Analysis.\",\"authors\":\"Eman E Shaban, Yavuz Yigit, Mohamed Elgassim, Ahmed Shaban, Amira Shaban, Amin Ameen, Mohamed Abdurabu, Hany A Zaki\",\"doi\":\"10.30476/BEAT.2024.102205.1504\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This study aimed to compare the clinical risks and outcomes of COVID-19 and influenza.</p><p><strong>Methods: </strong>The search for relevant articles was conducted using both a database search method and a manual search, which involved searching through the reference lists of articles related to the topic for additional studies. The Quality assessment was carried out using the Newcastle Ottawa tool, and the data analysis was conducted using the Review Manager Software (RevMan 5.4.1).</p><p><strong>Results: </strong>The meta-analysis results indicated that COVID-19 patients had similar lengths of hospital stays (SMD: -0.25; 95% CI: -0.60-0.11; <i>p</i>=0.17). However, COVID-19 patients had significantly higher mortality rates (RR: 0.28; 95% CI: 0.21-0.37; <i>p</i><0.0001), in-hospital complications (RR: 0.57; 95% CI: 0.50-0.65; <i>p</i><0.00001), intensive care unit (ICU) admissions (OR: 0.48; 95% CI: 0.37-0.61; <i>p</i><0.00001), length of ICU stay (SMD: -0.45; 95% CI: -0.83-0.06; <i>p</i>=0.02), and mechanical ventilation use (OR: 0.36; 95% CI: 0.28-0.46; <i>p</i><0.00001).</p><p><strong>Conclusion: </strong>The findings suggested that COVID-19 was more severe than influenza. Therefore, \\\"flu-like\\\" symptoms should not be dismissed without a clear diagnosis, especially during the winter when influenza is more prevalent.</p>\",\"PeriodicalId\":9333,\"journal\":{\"name\":\"Bulletin of emergency and trauma\",\"volume\":\"12 2\",\"pages\":\"47-57\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366268/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of emergency and trauma\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30476/BEAT.2024.102205.1504\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of emergency and trauma","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30476/BEAT.2024.102205.1504","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comparative Clinical Assessment and Risk Stratification of COVID-19 and Influenza Infections in Adults and Children: A Comprehensive Systematic Review and Meta-Analysis.
Objective: This study aimed to compare the clinical risks and outcomes of COVID-19 and influenza.
Methods: The search for relevant articles was conducted using both a database search method and a manual search, which involved searching through the reference lists of articles related to the topic for additional studies. The Quality assessment was carried out using the Newcastle Ottawa tool, and the data analysis was conducted using the Review Manager Software (RevMan 5.4.1).
Results: The meta-analysis results indicated that COVID-19 patients had similar lengths of hospital stays (SMD: -0.25; 95% CI: -0.60-0.11; p=0.17). However, COVID-19 patients had significantly higher mortality rates (RR: 0.28; 95% CI: 0.21-0.37; p<0.0001), in-hospital complications (RR: 0.57; 95% CI: 0.50-0.65; p<0.00001), intensive care unit (ICU) admissions (OR: 0.48; 95% CI: 0.37-0.61; p<0.00001), length of ICU stay (SMD: -0.45; 95% CI: -0.83-0.06; p=0.02), and mechanical ventilation use (OR: 0.36; 95% CI: 0.28-0.46; p<0.00001).
Conclusion: The findings suggested that COVID-19 was more severe than influenza. Therefore, "flu-like" symptoms should not be dismissed without a clear diagnosis, especially during the winter when influenza is more prevalent.
期刊介绍:
BEAT: Bulletin of Emergency And Trauma is an international, peer-reviewed, quarterly journal coping with original research contributing to the field of emergency medicine and trauma. BEAT is the official journal of the Trauma Research Center (TRC) of Shiraz University of Medical Sciences (SUMS), Hungarian Trauma Society (HTS) and Lusitanian Association for Trauma and Emergency Surgery (ALTEC/LATES) aiming to be a publication of international repute that serves as a medium for dissemination and exchange of scientific knowledge in the emergency medicine and trauma. The aim of BEAT is to publish original research focusing on practicing and training of emergency medicine and trauma to publish peer-reviewed articles of current international interest in the form of original articles, brief communications, reviews, case reports, clinical images, and letters.