Akshay A. Kolakar , Niranjana Mahantashetti , Mubashir Angolkar , Madan M. Godbole , Deshna Oswal
{"title":"营养补充剂对 Belagavi 市 12-18 个月儿童线性生长的影响:随机对照试验","authors":"Akshay A. Kolakar , Niranjana Mahantashetti , Mubashir Angolkar , Madan M. Godbole , Deshna Oswal","doi":"10.1016/j.cegh.2024.101774","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Adequate nutrition is one of the most important factors influencing growth & immunity. Bovine colostrum (BC) is the first milk produced after birth of a calf and is a rich natural source of macronutrients, micronutrients, immunoglobulins, growth factors and peptides with anti-microbial activity.</p></div><div><h3>Objective</h3><p>The current study was conducted to test the hypothesis whether BC supplementation would lead to an increase in linear growth of children of age 12–18 months. The secondary objectives were 1) To measure biomedical parameters among 12–18 months children in the 2 groups, i.e., BC and control group. 2) To assess the acceptability and tolerability of BC among children.</p></div><div><h3>Materials & methods</h3><p>A double blinded randomized control trial was conducted among children in the age group of 12–18 months. A total of 78 participants were included and were randomly divided into experiment and control groups. Anthropometric measurements and biochemical parameters were measured before and after intervention. The acceptability and tolerability of BC was assessed through a questionnaire filled by the mothers of study participant.</p></div><div><h3>Results</h3><p>There was a significant difference observed in Body mass index (BMI), Chest circumference and Mid upper arm circumference in the BC group but there was not any significant difference found in biochemical parameters. Mothers of study participant reported high acceptability and no side effects of the intervention.</p></div><div><h3>Conclusion</h3><p>Supplementation of BC in children's diet lead to improved anthropometric outcomes in children of Belagavi city and was acceptable by them.</p></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"29 ","pages":"Article 101774"},"PeriodicalIF":2.3000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213398424002719/pdfft?md5=6fa1e5176c5598b88495f9474605b330&pid=1-s2.0-S2213398424002719-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Impact of Nutrition Supplementation on linear growth among 12–18 months children of Belagavi city: A randomized control trial\",\"authors\":\"Akshay A. Kolakar , Niranjana Mahantashetti , Mubashir Angolkar , Madan M. Godbole , Deshna Oswal\",\"doi\":\"10.1016/j.cegh.2024.101774\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Adequate nutrition is one of the most important factors influencing growth & immunity. Bovine colostrum (BC) is the first milk produced after birth of a calf and is a rich natural source of macronutrients, micronutrients, immunoglobulins, growth factors and peptides with anti-microbial activity.</p></div><div><h3>Objective</h3><p>The current study was conducted to test the hypothesis whether BC supplementation would lead to an increase in linear growth of children of age 12–18 months. The secondary objectives were 1) To measure biomedical parameters among 12–18 months children in the 2 groups, i.e., BC and control group. 2) To assess the acceptability and tolerability of BC among children.</p></div><div><h3>Materials & methods</h3><p>A double blinded randomized control trial was conducted among children in the age group of 12–18 months. A total of 78 participants were included and were randomly divided into experiment and control groups. Anthropometric measurements and biochemical parameters were measured before and after intervention. The acceptability and tolerability of BC was assessed through a questionnaire filled by the mothers of study participant.</p></div><div><h3>Results</h3><p>There was a significant difference observed in Body mass index (BMI), Chest circumference and Mid upper arm circumference in the BC group but there was not any significant difference found in biochemical parameters. Mothers of study participant reported high acceptability and no side effects of the intervention.</p></div><div><h3>Conclusion</h3><p>Supplementation of BC in children's diet lead to improved anthropometric outcomes in children of Belagavi city and was acceptable by them.</p></div>\",\"PeriodicalId\":46404,\"journal\":{\"name\":\"Clinical Epidemiology and Global Health\",\"volume\":\"29 \",\"pages\":\"Article 101774\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2213398424002719/pdfft?md5=6fa1e5176c5598b88495f9474605b330&pid=1-s2.0-S2213398424002719-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Epidemiology and Global Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2213398424002719\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Epidemiology and Global Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213398424002719","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
摘要
背景充足的营养是影响生长和免疫的最重要因素之一。牛初乳(BC)是小牛出生后产生的第一口乳汁,是大量营养素、微量营养素、免疫球蛋白、生长因子和具有抗微生物活性的肽的丰富天然来源。次要目标是:1)测量两组(即 BC 组和对照组)12-18 个月儿童的生物医学参数。2)评估儿童对 BC 的接受度和耐受性。材料& 方法在 12-18 个月大的儿童中开展了一项双盲随机对照试验。共有 78 名参与者被随机分为实验组和对照组。干预前后测量了人体测量和生化指标。结果观察发现,BC 组的体重指数(BMI)、胸围和中上臂围有显著差异,但生化指标无显著差异。结论在儿童饮食中添加 BC 可改善 Belagavi 市儿童的人体测量结果,并为他们所接受。
Impact of Nutrition Supplementation on linear growth among 12–18 months children of Belagavi city: A randomized control trial
Background
Adequate nutrition is one of the most important factors influencing growth & immunity. Bovine colostrum (BC) is the first milk produced after birth of a calf and is a rich natural source of macronutrients, micronutrients, immunoglobulins, growth factors and peptides with anti-microbial activity.
Objective
The current study was conducted to test the hypothesis whether BC supplementation would lead to an increase in linear growth of children of age 12–18 months. The secondary objectives were 1) To measure biomedical parameters among 12–18 months children in the 2 groups, i.e., BC and control group. 2) To assess the acceptability and tolerability of BC among children.
Materials & methods
A double blinded randomized control trial was conducted among children in the age group of 12–18 months. A total of 78 participants were included and were randomly divided into experiment and control groups. Anthropometric measurements and biochemical parameters were measured before and after intervention. The acceptability and tolerability of BC was assessed through a questionnaire filled by the mothers of study participant.
Results
There was a significant difference observed in Body mass index (BMI), Chest circumference and Mid upper arm circumference in the BC group but there was not any significant difference found in biochemical parameters. Mothers of study participant reported high acceptability and no side effects of the intervention.
Conclusion
Supplementation of BC in children's diet lead to improved anthropometric outcomes in children of Belagavi city and was acceptable by them.
期刊介绍:
Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.