CEUS 结合 C-TIRADS 对 FNA 细胞学不确定甲状腺结节的诊断价值。

Wei-Bing Zhang, Wen-Fang Deng, Bei-Li He, Ying-Ying Wei, Yu Liu, Zhe Chen, Ren-Yan Xu
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引用次数: 0

摘要

目的探讨CEUS结合C-TIRADS对FNA细胞学甲状腺结节不确定性的诊断价值:方法:回顾性分析192例经手术病理证实的FNA细胞学甲状腺结节不确定患者的临床资料、超声图像、C-TIRADS分类和CEUS图像。计算了 CEUS、C-TIRADS 和 CEUS-TIRADS 的诊断效果:结果:CEUS、C-TIRADS 和 CEUS-TIRADS 的 AUC 分别为 0.905(95% CI:0.862∼0.949)、0.881(95% CI:0.825∼0.938)和 0.954(95% CI:0.922∼0.986)。灵敏度、特异性、PPV、NPV、准确度、LR- 和 LR+ 分别为 84.7%(116/137)、85.5%(47/55)、93.5%(116/124)、69.1%(47/68)、84.9%(163/192)、0.179、5.82 和 84.7%(116/137)、83.6%(46/55)、92.8%(116/125)、68.7%(46/67)、84.4%(162/192)、0.183、5.17、92.7%(127/137)、89.1%(49/55)、95.5%(127/133)、83.1%(49/59)、91.7%(176/192)、0.082 和 8.50。与 CEUS 和 C-TIRADS 相比,CEUS-TIRADS 的 AUC、灵敏度和准确度均有所提高(均为 P 结论:CEUS-TIRADS 的 AUC、灵敏度和准确度均高于 CEUS 和 C-TIRADS :CEUS和C-TIRADS对不确定的FNA细胞学甲状腺结节具有很高的诊断价值。CEUS-TIRADS提高了AUC、诊断灵敏度和准确性,有助于鉴别不确定的FNA细胞学结节。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnostic value of CEUS combined with C-TIRADS for indeterminate FNA cytological thyroid nodules.

Objectives: To investigate the diagnostic value of CEUS combined with C-TIRADS for indeterminate FNA cytological thyroid nodules.

Methods: The clinical data, ultrasonic images, C-TIRADS categories and CEUS images of 192 patients with indeterminate FNA cytological thyroid nodules confirmed by the surgical pathology were analyzed retrospectively. The diagnostic efficacy of CEUS, C-TIRADS and CEUS-TIRADS were calculated.

Results: The AUCs of CEUS, C-TIRADS and CEUS-TIRADS were 0.905 (95% CI: 0.862∼0.949), 0.881 (95% CI: 0.825∼0.938) and 0.954 (95% CI: 0.922∼0.986), respectively. The sensitivity, specificity, PPV, NPV, accuracy, LR- and LR+ were 84.7% (116/137), 85.5% (47/55), 93.5% (116/124), 69.1% (47/68), 84.9% (163/192), 0.179, 5.82 and 84.7% (116/137), 83.6% (46/55), 92.8% (116/125), 68.7% (46/67), 84.4% (162/192), 0.183, 5.17, 92.7% (127/137), 89.1% (49/55), 95.5% (127/133), 83.1% (49/59), 91.7% (176/192), 0.082, and 8.50, respectively. Compared with CEUS and C-TIRADS, CEUS-TIRADS had improved the AUC, sensitivity and accuracy (all P < 0.05).

Conclusions: CEUS and C-TIRADS had high diagnostic values in indeterminate FNA cytological thyroid nodules. CEUS-TIRADS improved AUC, diagnostic sensitivity and accuracy, and helped to distinguish indeterminate FNA cytological nodules.

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