{"title":"铊暴露与中国成年人肾功能下降的关系 - 中国，2017-2018年。","authors":"Zheng Zhang, Miao Zhang, Yingli Qu, Feng Zhao, Saisai Ji, Zheng Li, Bing Wu, Chunxian Lyu, Haocan Song, Qi Sun, Yawei Li, Xu Zhang, Xulin Zheng, Yidan Qiu, Zihan Lu, Hui Fu, Lanjing Xu, Wenli Zhang, Yufei Luo, Fangyu Li, Jiayi Cai, Yuanduo Zhu, Ying Zhu, Zhaojin Cao, Yuebin Lyu, Xiaoming Shi","doi":"10.46234/ccdcw2024.186","DOIUrl":null,"url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Thallium (Tl) is significantly more toxic than heavy metals such as lead, cadmium, and mercury. However, previous studies examining the relationship between Tl exposure and the risk of chronic kidney disease (CKD) have yielded inconsistent results.</p><p><strong>What is added by this report?: </strong>The study demonstrated that elevated urinary Tl levels were associated with a higher prevalence of CKD and a reduced estimated glomerular filtration rate (eGFR), particularly among older adults. These findings were consistent in the restricted cubic spline (RCS) analyses.</p><p><strong>What are the implications for public health practice?: </strong>This study identified Tl as a risk factor for decreased renal function, underscoring the need to enhance surveillance of Tl to mitigate the disease burden of CKD.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11350231/pdf/","citationCount":"0","resultStr":"{\"title\":\"Association of Thallium Exposure with Decreased Renal Function among Chinese Adults - China, 2017-2018.\",\"authors\":\"Zheng Zhang, Miao Zhang, Yingli Qu, Feng Zhao, Saisai Ji, Zheng Li, Bing Wu, Chunxian Lyu, Haocan Song, Qi Sun, Yawei Li, Xu Zhang, Xulin Zheng, Yidan Qiu, Zihan Lu, Hui Fu, Lanjing Xu, Wenli Zhang, Yufei Luo, Fangyu Li, Jiayi Cai, Yuanduo Zhu, Ying Zhu, Zhaojin Cao, Yuebin Lyu, Xiaoming Shi\",\"doi\":\"10.46234/ccdcw2024.186\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>What is already known about this topic?: </strong>Thallium (Tl) is significantly more toxic than heavy metals such as lead, cadmium, and mercury. However, previous studies examining the relationship between Tl exposure and the risk of chronic kidney disease (CKD) have yielded inconsistent results.</p><p><strong>What is added by this report?: </strong>The study demonstrated that elevated urinary Tl levels were associated with a higher prevalence of CKD and a reduced estimated glomerular filtration rate (eGFR), particularly among older adults. These findings were consistent in the restricted cubic spline (RCS) analyses.</p><p><strong>What are the implications for public health practice?: </strong>This study identified Tl as a risk factor for decreased renal function, underscoring the need to enhance surveillance of Tl to mitigate the disease burden of CKD.</p>\",\"PeriodicalId\":69039,\"journal\":{\"name\":\"中国疾病预防控制中心周报\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2024-08-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11350231/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国疾病预防控制中心周报\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.46234/ccdcw2024.186\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国疾病预防控制中心周报","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.46234/ccdcw2024.186","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Association of Thallium Exposure with Decreased Renal Function among Chinese Adults - China, 2017-2018.
What is already known about this topic?: Thallium (Tl) is significantly more toxic than heavy metals such as lead, cadmium, and mercury. However, previous studies examining the relationship between Tl exposure and the risk of chronic kidney disease (CKD) have yielded inconsistent results.
What is added by this report?: The study demonstrated that elevated urinary Tl levels were associated with a higher prevalence of CKD and a reduced estimated glomerular filtration rate (eGFR), particularly among older adults. These findings were consistent in the restricted cubic spline (RCS) analyses.
What are the implications for public health practice?: This study identified Tl as a risk factor for decreased renal function, underscoring the need to enhance surveillance of Tl to mitigate the disease burden of CKD.
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