咽浅鳞状细胞癌内窥镜切除术的效果和结果。

IF 2.3 3区医学 Q1 OTORHINOLARYNGOLOGY

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2024-08-29 DOI:10.1002/hed.27924

Naohiro Nakamura, Tomofumi Sakagami, Minaki Shimizu, Kensuke Suzuki, Takuo Fujisawa, Takuya Shijimaya, Sanshiro Kobayashi, Yu Takahashi, Tomomitsu Tahara, Yuri Noda, Koji Tsuta, Makoto Naganuma

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引用次数: 0

摘要

背景：随着内镜成像技术的发展，咽浅表鳞状细胞癌现在可以在常规内镜检查中发现。最近，有报道称内镜下切除浅表咽鳞状细胞癌的疗效显著：本研究采用回顾性单中心设计，纳入了接受内镜下切除术的浅表咽鳞状细胞癌患者。共对 47 例患者的 53 个病灶进行了分析：全切率和R0切除率分别为83.0%和56.6%。随访期间分别有1例和3例患者发现局部复发和宫颈淋巴结转移（CLNM）。宏观0-I型是CLNM的独立因素。内镜切除术后，3年累计咽鳞癌发生率为33.0%，5年总生存率为89.2%：结论：内镜下切除是治疗浅表咽鳞状细胞癌的有效方法，0-I型大体上是预测CLNM的有效指标。

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Effectiveness and outcomes of endoscopic resection for superficial pharyngeal squamous cell carcinomas.

Background: With the development of endoscopic imaging, superficial pharyngeal squamous cell carcinoma can now be detected during routine endoscopy. Recently, the effectiveness of endoscopic resection for superficial pharyngeal squamous cell carcinoma have been reported.

Methods: This study had a retrospective single-center design that included patients with superficial pharyngeal squamous cell carcinoma who underwent endoscopic resection. A total 47 patients with 53 lesions were analyzed.

Results: En bloc and R0 resection rates were 83.0% and 56.6%. Local recurrence and cervical lymph node metastasis (CLNM) were detected in 1 and 3 patients during follow-up. The macroscopic type 0-I was an independent factor for CLNM. The 3-year cumulative incidence of metachronous pharyngeal squamous cell carcinoma following endoscopic resection was 33.0%, and the 5-year overall survival rate was 89.2%.

Conclusions: Endoscopic resection is an effective treatment for superficial pharyngeal squamous cell carcinomas, and the macroscopic type 0-I is a useful predictor of CLNM.

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来源期刊

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 医学-耳鼻喉科学

CiteScore

7.00

自引率

6.90%

发文量

278

审稿时长

1.6 months

期刊介绍： Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.