评估利多卡因对狗耳睑神经阻滞的效果:起效、持续时间以及对眼压和眼部检查的影响。

IF 1.7 4区 农林科学 Q2 VETERINARY SCIENCES
Bahar Golzar, Ali Asghar Sarchahi, Mohammad Azizzadeh
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引用次数: 0

摘要

目的:准确测量眼内压(IOP)对管理青光眼至关重要,需要进行眼压测量。通常采用局部麻醉,但眼睑痉挛可能需要神经阻滞。本研究调查了使用利多卡因进行耳睑神经阻滞以达到眼睑痉挛的效果及其对狗眼压的影响:在一项随机、盲法试验中,12 只健康的成年混血犬(24 只眼)接受了 2% 利多卡因杏仁核神经阻滞术(n = 12 只眼)或无阻滞术(n = 12 只眼)。在阻滞/未阻滞的半数眼睛中使用四卡因滴眼液进行局部麻醉,其余眼睛使用人工泪液作为对照。通过评估阻滞前、滴入后和阻滞消散前每隔 15 分钟的威胁反应、睑反射和眼压来评估神经阻滞的影响:结果:15 分钟时,58.5%(7/12 只眼)的耳睑神经阻滞可有效缓解眼睑运动障碍,30 分钟时达到 91.7%(11/12 只眼),表明疗效达到顶峰。随后,阻滞作用逐渐减弱,分别有 66.7%(8/12 只眼睛)和 33.3%(4/12 只眼睛)在 45 分钟和 60 分钟时保持眼睑运动障碍。重要的是,耳廓睑神经阻滞和四卡因用药均未对眼压测量产生显著影响(P > .05):结论:使用利多卡因进行杏仁核神经阻滞能有效缓解眼睑运动障碍,在注射后 30 分钟达到高峰。这项技术被证明是安全的,而且眼压没有明显变化,这表明它在犬眼科需要眼睑运动的手术中具有潜在的实用性,尤其是在青光眼的治疗中,保持准确的眼压测量对于诊断、治疗和监测疾病至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of lidocaine for auriculopalpebral nerve block in dogs: Onset, duration, and effects on intraocular pressure and eye examination.

Objectives: Accurate intraocular pressure (IOP) measurement is essential for managing glaucoma, requiring tonometry. Local anesthesia is typically used, but nerve blocks may be needed for blepharospasm. This study investigated the efficacy of auriculopalpebral nerve block with lidocaine in achieving eyelid akinesia and its influence on IOP in dogs.

Animals and procedures: In a randomized, blinded trial, 12 healthy adult mixed-breed dogs (24 eyes) received either auriculopalpebral nerve block with 2% lidocaine (n = 12 eyes) or no block (n = 12 eyes). Tetracaine drops were used for topical anesthesia in half of blocked/non-blocked eyes, and the rest of the eyes got artificial tears as control. The impact of nerve block was evaluated through assessments of menace response, palpebral reflex, and IOP before the block, after drop instillation, and at 15-min intervals until block dissipation.

Results: Auriculopalpebral nerve block provided effective eyelid akinesia in 58.5% (7/12 eyes) at 15 min, reaching 91.7% (11/12 eyes) at 30 min, indicating peak efficacy. Subsequently, the block gradually diminished, with 66.7% (8/12 eyes) and 33.3% (4/12 eyes) maintaining akinesia at 45 and 60 min, respectively. Importantly, neither auriculopalpebral nerve block nor tetracaine administration significantly affected IOP measurements (p > .05).

Conclusions: Auriculopalpebral nerve block using lidocaine demonstrated efficient eyelid akinesia, peaking at 30 min postinjection. This technique proved to be safe with no notable alterations in IOP, suggesting its potential utility in canine ophthalmology for procedures requiring eyelid akinesia, particularly in the management of glaucoma where maintaining accurate IOP measurements is crucial for diagnosis, treatment, and monitoring the disease.

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来源期刊
Veterinary ophthalmology
Veterinary ophthalmology 农林科学-兽医学
CiteScore
2.70
自引率
37.50%
发文量
82
审稿时长
12-24 weeks
期刊介绍: Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of: Clinical and investigational veterinary and comparative ophthalmology; Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species; Experimental models of both animal and human ocular disease in veterinary species; Anatomic studies of the animal eye; Physiological studies of the animal eye; Pharmacological studies of the animal eye.
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