假冒伪劣药品风险的全球视角:文献批判性综述》。

IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES
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引用次数: 0

摘要

背景:伪造和假冒药品在全球日益猖獗,给国际旅行者带来了风险。这篇叙述性文献综述探讨了伪造和假冒药品在全球范围内带来的挑战,并特别关注旅行者面临的风险。目的是全面了解这一多层面问题,探讨有效干预的潜在解决方案:对包括 PubMed、MEDLINE 和 Scopus 在内的数据库以及国际组织的相关报告进行了全面搜索。重点是提取与国际旅行者遇到的伪造和假冒药品的流行率、类型和地域模式有关的信息。综合这些信息有助于确定总体趋势和模式。本叙述性综述采用主题分析法对研究结果进行综合:研究结果表明,假药种类繁多,从抗生素到生活方式用药,给在全球药品市场中穿梭的旅行者带来了独特的风险。审查强调了这些药物的地理分布,对高收入和低收入国家造成的后果各不相同。这些做法造成的配方不当和药物释放不一致对公众健康构成了严重威胁,尤其是对出国旅行的个人而言。本综述还强调了国际合作在应对这一全球性挑战方面的重要性,因为药品供应链无缝跨越国界,需要采取合作方式进行有效监管和执法:本综述强调有必要开展有针对性的研究、合作干预和技术创新,以解决与伪造和假冒药品相关的复杂问题,确保国际旅行者的安全和福祉。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Global perspective of the risks of falsified and counterfeit medicines: A critical review of the literature

Background

The increasing prevalence of falsified and counterfeit medicines globally poses risks to international travellers. This narrative literature review examines the global challenge of falsified and counterfeit medicines, with a specific focus on risks for travellers. The aim is to provide a comprehensive understanding of this multidimensional issue, exploring potential solutions for effective intervention.

Methods

A comprehensive search of databases, including PubMed, MEDLINE, and Scopus, as well as relevant reports from international organisations, was undertaken. There was a focus on extracting information pertaining to the prevalence, types, and geographical patterns of falsified and counterfeit medicines encountered by international travellers. Synthesising this information helped to identify overarching trends and patterns. This narrative review utilised a thematic analysis approach to synthesise the findings.

Results

The findings revealed a diverse range of counterfeit drug categories, spanning from antibiotics to lifestyle medications, posing unique risks to travellers navigating the global pharmaceutical landscape. The review emphasises the geographical distribution of these drugs, with varying consequences for both high- and low-income nations. The inadequate formulations and inconsistent drug release arising from these practices pose severe threats to public health, especially for individuals travelling abroad. The review also highlights the significance of international collaboration in addressing this global challenge, as pharmaceutical supply chains seamlessly cross borders, necessitating a collaborative approach for effective regulation and enforcement.

Conclusions

This review underscores the need for targeted research, collaborative interventions, and technological innovations to address the complexities associated with falsified and counterfeit medicines, ensuring the safety and well-being of international travellers.

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来源期刊
Travel Medicine and Infectious Disease
Travel Medicine and Infectious Disease PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-INFECTIOUS DISEASES
CiteScore
19.40
自引率
1.70%
发文量
211
审稿时长
49 days
期刊介绍: Travel Medicine and Infectious Disease Publication Scope: Publishes original papers, reviews, and consensus papers Primary theme: infectious disease in the context of travel medicine Focus Areas: Epidemiology and surveillance of travel-related illness Prevention and treatment of travel-associated infections Malaria prevention and treatment Travellers' diarrhoea Infections associated with mass gatherings Migration-related infections Vaccines and vaccine-preventable disease Global policy/regulations for disease prevention and control Practical clinical issues for travel and tropical medicine practitioners Coverage: Addresses areas of controversy and debate in travel medicine Aims to inform guidelines and policy pertinent to travel medicine and the prevention of infectious disease Publication Features: Offers a fast peer-review process Provides early online publication of accepted manuscripts Aims to publish cutting-edge papers
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