产前诊断为脐膨出和胃裂的围产期结果:一家大学医院的调查。

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY
Riza Madazli, Didem Kaymak, Görkem Arıca, Zafer Başıbüyük, Ebru Alıcı Davutoğlu, Zeynep Alp Ünkar
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引用次数: 0

摘要

摘要评估产前诊断为脐膨出和胃裂的胎儿的临床特征和围产期结局:这是一项回顾性、单中心、队列研究,对象是在一家大学医院随访和分娩的产前诊断为脐膨出和胃裂的胎儿。研究比较了胃畸形和脐膨出胎儿的人口统计学、妊娠、出生和围产期结局:结果:共评估了 75 例脐带绕颈胎儿和 21 例胃螺裂胎儿。怀有脐膨出胎儿的产妇的平均年龄明显高于怀有胃畸形胎儿的产妇(P=0.001)。分别有 53.3% 和 4.7% 的脐带绕颈胎儿和胃裂胎儿伴有结构异常(P=0.001):与患有胃裂的胎儿相比,患有脐膨出的胎儿中伴有结构和染色体异常的比例明显更高。脐膨出胎儿的预后取决于相关的结构和染色体异常,而肠道受损则是胃畸形的主要决定因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Perinatal outcomes of antenatally diagnosed omphalocele and gastroschisis: a survey from a university hospital.

Objective: To evaluate the clinical features and perinatal outcomes of antenatally diagnosed fetuses with omphalocele and gastroschisis.

Material and methods: This was a retrospective, single-center, cohort study of prenatally diagnosed fetuses with omphalocele and gastroschisis followed-up and delivered at a university hospital. Demographic, pregnancy, birth and perinatal outcomes were compared between gastroschisis and omphalocele.

Results: A total of 75 fetuses with omphalocele and 21 cases with gastroschisis were evaluated. The mean maternal age of women carrying a fetus with omphalocele was significantly higher than the women with gastroschisis (p=0.001). Associated structural anomalies were found in 53.3% and 4.7% of fetuses with omphalocele and gastroschisis, respectively (p<0.001). The rate of chromosomal anomaly was 8.3% in pregnancies with omphalocele. In liveborn pregnancies, the mean gestational age at delivery and birth weight did not differ between the study groups. Time to postoperative oral intake, duration of parenteral nutrition and length of hospital stay were significantly longer in babies with gastroschisis than omphalocele (p<0.01). Rates of termination, intrauterine, neonatal and infant death of fetuses with omphalocele were 25.3%, 6.7%, 10.7% and 2.7% respectively. Time to postoperative oral intake, duration of parenteral nutrition and duration of hospitalization were significantly longer in babies with complex compared to simple gastroschisis (p<0.01). Survival rates were 95.2%, 82.9% and 20% in fetuses with gastroschisis, isolated and non-isolated omphalocele, respectively.

Conclusion: Associated structural and chromosomal anomalies were significantly more common in fetuses with omphalocele compared to those with gastroschisis. Prognosis of fetuses with omphalocele depended on the associated structural and chromosomal anomalies, whereas bowel compromise was the main determining factor in gastroschisis.

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来源期刊
CiteScore
2.40
自引率
7.10%
发文量
56
期刊介绍: Journal of the Turkish-German Gynecological Association is the official, open access publication of the Turkish-German Gynecological Education and Research Foundation and Turkish-German Gynecological Association and is published quarterly on March, June, September and December. It is an independent peer-reviewed international journal printed in English language. Manuscripts are reviewed in accordance with “double-blind peer review” process for both reviewers and authors. The target audience of Journal of the Turkish-German Gynecological Association includes gynecologists and primary care physicians interested in gynecology practice. It publishes original works on all aspects of obstertrics and gynecology. The aim of Journal of the Turkish-German Gynecological Association is to publish high quality original research articles. In addition to research articles, reviews, editorials, letters to the editor, diagnostic puzzle are also published. Suggestions for new books are also welcomed. Journal of the Turkish-German Gynecological Association does not charge any fee for article submission or processing.
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