Niwut Juntavee, Apa Juntavee, Chansin Khunngoen, Akarin Singpromma, Warun Khoosuwan
{"title":"apacider凝胶对陶瓷修复体边缘周围釉质和骨水泥的再矿化潜力。","authors":"Niwut Juntavee, Apa Juntavee, Chansin Khunngoen, Akarin Singpromma, Warun Khoosuwan","doi":"10.4317/jced.61629","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Modern management of carious lesions has been targeted upon using remineralizing agents. This study investigated the remineralization potential of apacider gel (AG) and casein phosphopeptide-amorphous calcium fluoride phosphate (CA) on enamel and cementum around the cavosurface area of the ceramic margin.</p><p><strong>Material and methods: </strong>Seventy-five extracted human mandibular molars were sectioned at 0.8 mm above and below the cemento-enamel junction (CEJ) to remove the CEJ portions and replaced them with glass ceramic disks by bonding them to the crown and root portions with resin cement. The enamel and cementum area of 4x4 mm2 surrounding ceramic was demineralized with Carbopol-907. The demineralized surfaces were treated with either AG or CA, while one group was left with no treatment (NT) and served as control. Vickers microhardness was determined before-, after demineralization, and after remineralization. The percentage of hardness recovery (%HR), and remineralization potential (%RP) were analyzed with ANOVA and Bonferroni's test (α=0.05). Polarized light microscopy (PLM) was assessed for lesion depth. Scanning electron microscopy (SEM) was investigated for surface alterations.</p><p><strong>Results: </strong>Significant differences in remineralization were found upon various remineralizing agents compared to NT for both enamel and cementum (<i>p</i><0.05). No significant difference in %HR and %RP was observed between AG and CA (<i>p</i>>0.05). However, AG signified greater decrease in lesion depth and better improvement in surface characteristics for both enamel and cementum than CA.</p><p><strong>Conclusions: </strong>AG possesses comparable remineralization ability to CA. However, decreasing in carious lesion depth was evinced with using AG more than CA. AG was recommended as a potential remineralization material for handling initial caries for both enamel and cementum. <b>Key words:</b>Apacider, artificial carious lesion, CCP-ACFP, remineralizationCare Team.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 7","pages":"e851-e864"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11360458/pdf/","citationCount":"0","resultStr":"{\"title\":\"Remineralization potential of apacider gel on enamel and cementum surrounding margin of ceramic restoration.\",\"authors\":\"Niwut Juntavee, Apa Juntavee, Chansin Khunngoen, Akarin Singpromma, Warun Khoosuwan\",\"doi\":\"10.4317/jced.61629\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Modern management of carious lesions has been targeted upon using remineralizing agents. This study investigated the remineralization potential of apacider gel (AG) and casein phosphopeptide-amorphous calcium fluoride phosphate (CA) on enamel and cementum around the cavosurface area of the ceramic margin.</p><p><strong>Material and methods: </strong>Seventy-five extracted human mandibular molars were sectioned at 0.8 mm above and below the cemento-enamel junction (CEJ) to remove the CEJ portions and replaced them with glass ceramic disks by bonding them to the crown and root portions with resin cement. The enamel and cementum area of 4x4 mm2 surrounding ceramic was demineralized with Carbopol-907. The demineralized surfaces were treated with either AG or CA, while one group was left with no treatment (NT) and served as control. Vickers microhardness was determined before-, after demineralization, and after remineralization. The percentage of hardness recovery (%HR), and remineralization potential (%RP) were analyzed with ANOVA and Bonferroni's test (α=0.05). Polarized light microscopy (PLM) was assessed for lesion depth. Scanning electron microscopy (SEM) was investigated for surface alterations.</p><p><strong>Results: </strong>Significant differences in remineralization were found upon various remineralizing agents compared to NT for both enamel and cementum (<i>p</i><0.05). No significant difference in %HR and %RP was observed between AG and CA (<i>p</i>>0.05). However, AG signified greater decrease in lesion depth and better improvement in surface characteristics for both enamel and cementum than CA.</p><p><strong>Conclusions: </strong>AG possesses comparable remineralization ability to CA. However, decreasing in carious lesion depth was evinced with using AG more than CA. 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引用次数: 0
摘要
背景:现代治疗龋齿的方法主要是使用再矿化剂。本研究调查了apacider凝胶(AG)和酪蛋白磷酸肽-无定形氟化钙磷酸酯(CA)对陶瓷边缘龋面区域周围的牙釉质和牙本质的再矿化潜力:将 75 颗拔出的人类下颌磨牙在牙本质-牙釉质交界处(CEJ)上下 0.8 毫米处切开,去除 CEJ 部分,并用树脂粘结剂将玻璃陶瓷盘粘结到牙冠和牙根部分,以取代 CEJ 部分。用 Carbopol-907 对陶瓷周围 4x4 平方毫米的牙釉质和牙本质进行脱矿处理。用 AG 或 CA 对脱矿表面进行处理,一组不进行处理(NT),作为对照组。在去矿物质前、去矿物质后和再矿物质化后测定维氏硬度。硬度恢复百分比(%HR)和再矿化潜力(%RP)采用方差分析和邦费罗尼检验(α=0.05)进行分析。偏光显微镜(PLM)对病变深度进行评估。扫描电子显微镜(SEM)检查表面变化:在牙釉质和牙本质中,各种再矿化剂的再矿化效果与 NT 相比有显著差异(pp>0.05)。然而,与 CA 相比,AG 能更大程度地降低病变深度,更好地改善珐琅质和牙本质的表面特征:AG的再矿化能力与CA相当。结论:AG的再矿化能力与CA相当,但AG比CA更能降低龋损深度。建议将AG作为处理釉质和牙本质初期龋的潜在再矿化材料。关键字:Apacider、人工龋损、CCP-ACFP、再矿化护理团队。
Remineralization potential of apacider gel on enamel and cementum surrounding margin of ceramic restoration.
Background: Modern management of carious lesions has been targeted upon using remineralizing agents. This study investigated the remineralization potential of apacider gel (AG) and casein phosphopeptide-amorphous calcium fluoride phosphate (CA) on enamel and cementum around the cavosurface area of the ceramic margin.
Material and methods: Seventy-five extracted human mandibular molars were sectioned at 0.8 mm above and below the cemento-enamel junction (CEJ) to remove the CEJ portions and replaced them with glass ceramic disks by bonding them to the crown and root portions with resin cement. The enamel and cementum area of 4x4 mm2 surrounding ceramic was demineralized with Carbopol-907. The demineralized surfaces were treated with either AG or CA, while one group was left with no treatment (NT) and served as control. Vickers microhardness was determined before-, after demineralization, and after remineralization. The percentage of hardness recovery (%HR), and remineralization potential (%RP) were analyzed with ANOVA and Bonferroni's test (α=0.05). Polarized light microscopy (PLM) was assessed for lesion depth. Scanning electron microscopy (SEM) was investigated for surface alterations.
Results: Significant differences in remineralization were found upon various remineralizing agents compared to NT for both enamel and cementum (p<0.05). No significant difference in %HR and %RP was observed between AG and CA (p>0.05). However, AG signified greater decrease in lesion depth and better improvement in surface characteristics for both enamel and cementum than CA.
Conclusions: AG possesses comparable remineralization ability to CA. However, decreasing in carious lesion depth was evinced with using AG more than CA. AG was recommended as a potential remineralization material for handling initial caries for both enamel and cementum. Key words:Apacider, artificial carious lesion, CCP-ACFP, remineralizationCare Team.
期刊介绍:
Indexed in PUBMED, PubMed Central® (PMC) since 2012 and SCOPUSJournal of Clinical and Experimental Dentistry is an Open Access (free access on-line) - http://www.medicinaoral.com/odo/indice.htm. The aim of the Journal of Clinical and Experimental Dentistry is: - Periodontology - Community and Preventive Dentistry - Esthetic Dentistry - Biomaterials and Bioengineering in Dentistry - Operative Dentistry and Endodontics - Prosthetic Dentistry - Orthodontics - Oral Medicine and Pathology - Odontostomatology for the disabled or special patients - Oral Surgery