利用自动三维动态平衡 SSFP MRI 分段评估主动脉运动。

IF 4.2 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Renske Merton, Daan Bosshardt, Gustav J Strijkers, Aart J Nederveen, Eric M Schrauben, Pim van Ooij
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引用次数: 0

摘要

目的:应用自由运行的三维(3D)椎管平衡稳态自由前冲(bSSFP)CMR框架,结合人工智能分割,量化时间分辨的主动脉位移、直径和直径变化:在这项前瞻性研究中,我们利用伪螺旋笛卡尔欠采样和压缩传感重建技术,实施了一个扫描时间约为 4 分钟的自由运行 3D cine bSSFP 序列。通过使用 nnU-Net,对所有心脏时间帧进行了自动分割。为每名志愿者重复扫描三次绘制动态三维运动图,从而对运动以及升主动脉直径的测量和变化进行详细量化:共纳入了 14 名成年健康志愿者(中位年龄 28 岁(IQR:26.0-31.3),6 名女性)。主动脉测试集的自动分割与手动分割相比,Dice 得分为 0.93 ± 0.02。在所有志愿者中,第一次扫描时升主动脉(AAo)最大位移和平均位移的中位数(四分位数间距)分别为 13.0 (4.4) 毫米和 5.6 (2.4) 毫米。升主动脉的峰值平均直径为 25.9 (2.2) 毫米,峰值平均直径变化为 1.4 (0.5) 毫米。在三次重复扫描中,AAo 最大位移和平均位移的最大个体差异分别为 3.9 (1.6) 毫米和 2.2 (0.8) 毫米。平均直径和直径变化的最大个体差异分别为 1.2 (0.5) 毫米和 0.9 (0.4) 毫米:结论:扫描时间为四分钟的自由运行三维 cine bSSFP CMR 扫描与自动 nnU 网分割相结合,可持续捕捉主动脉与心脏运动相关的四维位移、直径和直径变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessing aortic motion with automated 3D cine balanced steady state free precession cardiovascular magnetic resonance segmentation.

Purpose: To apply a free-running three-dimensional (3D) cine balanced steady state free precession (bSSFP) cardiovascular magnetic resonance (CMR) framework in combination with artificial intelligence (AI) segmentations to quantify time-resolved aortic displacement, diameter and diameter change.

Methods: In this prospective study, we implemented a free-running 3D cine bSSFP sequence with scan time of approximately 4 min facilitated by pseudo-spiral Cartesian undersampling and compressed-sensing reconstruction. Automated segmentation of the aorta in all cardiac timeframes was applied through the use of nnU-Net. Dynamic 3D motion maps were created for three repeated scans per volunteer, leading to the detailed quantification of aortic motion, as well as the measurement and change in diameter of the ascending aorta.

Results: A total of 14 adult healthy volunteers (median age, 28 years (interquartile range [IQR]: 26.0-31.3), 6 females) were included. Automated segmentation compared to manual segmentation of the aorta test set showed a Dice score of 0.93 ± 0.02. The median (IQR) over all volunteers for the largest maximum and mean ascending aorta (AAo) displacement in the first scan was 13.0 (4.4) mm and 5.6 (2.4) mm, respectively. Peak mean diameter in the AAo was 25.9 (2.2) mm and peak mean diameter change was 1.4 (0.5) mm. The maximum individual variability over the three repeated scans of maximum and mean AAo displacement was 3.9 (1.6) mm and 2.2 (0.8) mm, respectively. The maximum individual variability of mean diameter and diameter change were 1.2 (0.5) mm and 0.9 (0.4) mm.

Conclusion: A free-running 3D cine bSSFP CMR scan with a scan time of four minutes combined with an automated nnU-net segmentation consistently captured the aorta's cardiac motion-related 4D displacement, diameter, and diameter change.

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来源期刊
CiteScore
10.90
自引率
12.50%
发文量
61
审稿时长
6-12 weeks
期刊介绍: Journal of Cardiovascular Magnetic Resonance (JCMR) publishes high-quality articles on all aspects of basic, translational and clinical research on the design, development, manufacture, and evaluation of cardiovascular magnetic resonance (CMR) methods applied to the cardiovascular system. Topical areas include, but are not limited to: New applications of magnetic resonance to improve the diagnostic strategies, risk stratification, characterization and management of diseases affecting the cardiovascular system. New methods to enhance or accelerate image acquisition and data analysis. Results of multicenter, or larger single-center studies that provide insight into the utility of CMR. Basic biological perceptions derived by CMR methods.
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