床旁超声评估静脉超声分级系统结合 TyG 指数在预测急性高脂血症性胰腺炎患者急性肾损伤中的价值

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Lingling He, Tinglong Huang, Long Xie
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引用次数: 0

摘要

目的/背景 床边超声评估静脉过度超声(VExUS)与甘油三酯-葡萄糖(TyG)指数相结合,在预测急性高脂血症性胰腺炎患者的急性肾损伤(AKI)方面发挥着重要作用。VExUS 可以有效评估静脉充血的程度,而 TyG 指数则对预测重症胰腺炎很有价值。这两种方法的结合有望为临床实践提供更准确的 AKI 风险评估工具。本研究探讨了结合使用 VExUS 分级系统和 TyG 指数进行床旁超声评估在预测急性高脂血症性胰腺炎患者急性肾损伤方面的价值。方法 从 2021 年 1 月至 2023 年 12 月,选取 110 例急性高脂血症性胰腺炎患者。根据是否并发急性肾损伤(AKI)将患者分为两组:AKI 组(23 人)和非 AKI 组(87 人)。比较两组的一般数据,并使用多变量逻辑回归分析急性高脂血症性胰腺炎患者发生 AKI 的风险因素。预测值采用接收器操作特征曲线(ROC)分析法进行评估。结果 患者的年龄、性别、预后、入院时的甘油三酯(TG)、总胆固醇、低密度脂蛋白(LDL)水平、出院时的血液营养状况、出院时的肌酐(CREA)水平、基础疾病、肠内营养开始时间、并发症等均无统计学差异、基础疾病、肠内营养开始时间、并发症、住院时间、重症监护室(ICU)天数、急性生理学和慢性健康评价 II(APACHE II)评分、血糖水平、血淀粉酶水平、CREA、血尿素氮(BUN)、血液净化治疗(P > 0.05).然而,TyG指数和VExUS评分之间存在明显差异(p < 0.05),变量包括TyG指数和VExUS评分(作为变量纳入逻辑回归分析),AKI(AKI = 1,非AKI = 0)作为因变量。多元逻辑回归结果显示,TyG指数和VExUS评分是急性高脂血症胰腺炎患者AKI的独立预测因子(P<0.05)。TyG指数、VExUS评分和联合模型预测这些患者AKI的标准误差、敏感性和特异性分别为0.064、73.91和87.45;0.036、78.16和95.65;0.010、100.00和95.65(P<0.05)。结论 VExUS 评分与 TyG 指数相结合,对预测急性高脂血症性胰腺炎患者的 AKI 具有很高的价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Value of Bedside Ultrasound Evaluation of Intravenous Ultrasound Grading System Combined with TyG Index in Predicting Acute Renal Injury in Patients with Acute Hyperlipidemic Pancreatitis.

Aims/Background Bedside ultrasound evaluation of venous excess ultrasound (VExUS) combined with the triglyceride-glucose (TyG) index plays an important role in predicting acute kidney injury (AKI) in patients with acute hyperlipidemic pancreatitis. VExUS can effectively evaluate the degree of venous congestion, while the TyG index is valuable in predicting severe pancreatitis. The combination of these two methods is expected to provide a more accurate AKI risk assessment tool for clinical practice. This study explores the value of combining bedside ultrasound evaluation using the VExUS grading system with the TyG index in predicting acute renal damage in patients with acute hyperlipidemic pancreatitis. Methods From January 2021 to December 2023, 110 patients with acute hyperlipidemic pancreatitis were selected. The patients were divided into two groups based on whether they were complicated with acute kidney injury (AKI): the AKI group (n = 23) and the non-AKI group (n = 87). The general data of the two groups were compared, and the risk factors for AKI in patients with acute hyperlipidemic pancreatitis were analyzed using multivariate logistic regression. The predictive value was assessed using receiver operating characteristic curve (ROC) analysis. Results There were no statistically significant differences in age, gender, outcome, triglyceride (TG), total cholesterol, low-density lipoprotein (LDL) levels at admission, blood nutrition at discharge, creatinine (CREA) at discharge, underlying diseases, start time of enteral nutrition, complications, length of stay, Intensive Care Unit (ICU) days, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, blood glucose level, blood amylase level, CREA, blood urine nitrogen (BUN), blood purification treatment (p > 0.05). However, there were significant differences (p < 0.05) between the TyG index and the VExUS score, with variables including the TyG index and the VExUS score (included in the logistic regression analysis as variables), and AKI (AKI = 1, non-AKI = 0) as dependent variables. Multiple logistic regression results showed that the TyG index and VExUS score were independent predictors of AKI in patients with acute hyperlipidemia pancreatitis (p < 0.05). The standard error, sensitivity and specificity of the TyG index, VExUS score and combined model for predicting AKI in these patients were 0.064, 73.91 and 87.45; 0.036, 78.16 and 95.65; 0.010, 100.00 and 95.65, respectively (p < 0.05). Conclusion The VExUS score combined with the TyG index is highly valuable in predicting AKI in patients with acute hyperlipidemic pancreatitis.

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来源期刊
British journal of hospital medicine
British journal of hospital medicine 医学-医学:内科
CiteScore
1.50
自引率
0.00%
发文量
176
审稿时长
4-8 weeks
期刊介绍: British Journal of Hospital Medicine was established in 1966, and is still true to its origins: a monthly, peer-reviewed, multidisciplinary review journal for hospital doctors and doctors in training. The journal publishes an authoritative mix of clinical reviews, education and training updates, quality improvement projects and case reports, and book reviews from recognized leaders in the profession. The Core Training for Doctors section provides clinical information in an easily accessible format for doctors in training. British Journal of Hospital Medicine is an invaluable resource for hospital doctors at all stages of their career. The journal is indexed on Medline, CINAHL, the Sociedad Iberoamericana de Información Científica and Scopus.
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