Allison Magnuson DO, MS, Kah Poh Loh MBBCh BAO, MS, Fiona Stauffer MS, William Dale MD, PhD, Nikesha Gilmore PhD, MS, Sindhuja Kadambi MD, Heidi D. Klepin MD, MS, Kaitlin Kyi MD, Lisa M. Lowenstein PhD, Tanyanika Phillips MD, MPH, Erika Ramsdale MD, MS, Melody K. Schiaffino PhD, MPH, John F. Simmons Jr MD, Grant R. Williams MD, MSPH, Jason Zittel MD, Supriya Mohile MD, MS
{"title":"临床执业医师的老年病评估:为什么、做什么、怎么做","authors":"Allison Magnuson DO, MS, Kah Poh Loh MBBCh BAO, MS, Fiona Stauffer MS, William Dale MD, PhD, Nikesha Gilmore PhD, MS, Sindhuja Kadambi MD, Heidi D. Klepin MD, MS, Kaitlin Kyi MD, Lisa M. Lowenstein PhD, Tanyanika Phillips MD, MPH, Erika Ramsdale MD, MS, Melody K. Schiaffino PhD, MPH, John F. Simmons Jr MD, Grant R. Williams MD, MSPH, Jason Zittel MD, Supriya Mohile MD, MS","doi":"10.3322/caac.21864","DOIUrl":null,"url":null,"abstract":"<p>Older adults with cancer heterogeneously experience health care, treatment, and symptoms. Geriatric assessment (GA) offers a comprehensive evaluation of an older individual's health status and can predict cancer-related outcomes in individuals with solid tumors and those with hematologic malignancies. In the last decade, randomized controlled trials have demonstrated the benefits of GA and GA management (GAM), which uses GA information to provide tailored intervention strategies to address GA impairments (e.g., implementing physical therapy for impaired physical function). Multiple phase 3 clinical trials in older adults with solid tumors and hematologic malignancies have demonstrated that GAM improves treatment completion, quality of life, communication, and advance care planning while reducing treatment-related toxicity, falls, and polypharmacy. Nonetheless, implementation and uptake of GAM remain challenging. Various strategies have been proposed, including the use of GA screening tools, to identify patients most likely to benefit from GAM, the systematic engagement of the oncology workforce in the delivery of GAM, and the integration of technologies like telemedicine and mobile health to enhance the availability of GA and GAM interventions. Health inequities in minoritized groups persist, and systematic GA implementation has the potential to capture social determinants of health that are relevant to equitable care. Caregivers play an important role in cancer care and experience burden themselves. GA can guide dyadic supportive care interventions, ultimately helping both patients and caregivers achieve optimal health.</p>","PeriodicalId":137,"journal":{"name":"CA: A Cancer Journal for Clinicians","volume":"74 6","pages":"496-518"},"PeriodicalIF":503.1000,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.3322/caac.21864","citationCount":"0","resultStr":"{\"title\":\"Geriatric assessment for the practicing clinician: The why, what, and how\",\"authors\":\"Allison Magnuson DO, MS, Kah Poh Loh MBBCh BAO, MS, Fiona Stauffer MS, William Dale MD, PhD, Nikesha Gilmore PhD, MS, Sindhuja Kadambi MD, Heidi D. Klepin MD, MS, Kaitlin Kyi MD, Lisa M. Lowenstein PhD, Tanyanika Phillips MD, MPH, Erika Ramsdale MD, MS, Melody K. Schiaffino PhD, MPH, John F. Simmons Jr MD, Grant R. Williams MD, MSPH, Jason Zittel MD, Supriya Mohile MD, MS\",\"doi\":\"10.3322/caac.21864\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Older adults with cancer heterogeneously experience health care, treatment, and symptoms. Geriatric assessment (GA) offers a comprehensive evaluation of an older individual's health status and can predict cancer-related outcomes in individuals with solid tumors and those with hematologic malignancies. In the last decade, randomized controlled trials have demonstrated the benefits of GA and GA management (GAM), which uses GA information to provide tailored intervention strategies to address GA impairments (e.g., implementing physical therapy for impaired physical function). Multiple phase 3 clinical trials in older adults with solid tumors and hematologic malignancies have demonstrated that GAM improves treatment completion, quality of life, communication, and advance care planning while reducing treatment-related toxicity, falls, and polypharmacy. Nonetheless, implementation and uptake of GAM remain challenging. Various strategies have been proposed, including the use of GA screening tools, to identify patients most likely to benefit from GAM, the systematic engagement of the oncology workforce in the delivery of GAM, and the integration of technologies like telemedicine and mobile health to enhance the availability of GA and GAM interventions. Health inequities in minoritized groups persist, and systematic GA implementation has the potential to capture social determinants of health that are relevant to equitable care. Caregivers play an important role in cancer care and experience burden themselves. 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Geriatric assessment for the practicing clinician: The why, what, and how
Older adults with cancer heterogeneously experience health care, treatment, and symptoms. Geriatric assessment (GA) offers a comprehensive evaluation of an older individual's health status and can predict cancer-related outcomes in individuals with solid tumors and those with hematologic malignancies. In the last decade, randomized controlled trials have demonstrated the benefits of GA and GA management (GAM), which uses GA information to provide tailored intervention strategies to address GA impairments (e.g., implementing physical therapy for impaired physical function). Multiple phase 3 clinical trials in older adults with solid tumors and hematologic malignancies have demonstrated that GAM improves treatment completion, quality of life, communication, and advance care planning while reducing treatment-related toxicity, falls, and polypharmacy. Nonetheless, implementation and uptake of GAM remain challenging. Various strategies have been proposed, including the use of GA screening tools, to identify patients most likely to benefit from GAM, the systematic engagement of the oncology workforce in the delivery of GAM, and the integration of technologies like telemedicine and mobile health to enhance the availability of GA and GAM interventions. Health inequities in minoritized groups persist, and systematic GA implementation has the potential to capture social determinants of health that are relevant to equitable care. Caregivers play an important role in cancer care and experience burden themselves. GA can guide dyadic supportive care interventions, ultimately helping both patients and caregivers achieve optimal health.
期刊介绍:
CA: A Cancer Journal for Clinicians" has been published by the American Cancer Society since 1950, making it one of the oldest peer-reviewed journals in oncology. It maintains the highest impact factor among all ISI-ranked journals. The journal effectively reaches a broad and diverse audience of health professionals, offering a unique platform to disseminate information on cancer prevention, early detection, various treatment modalities, palliative care, advocacy matters, quality-of-life topics, and more. As the premier journal of the American Cancer Society, it publishes mission-driven content that significantly influences patient care.