质疑因果关系声明中未经核实的假设:燃气灶会增加小儿哮喘的风险吗?

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引用次数: 0

摘要

使用未经验证的模型进行风险估算和政策建议可能会产生很大的误导,因为其预测可能无法反映真实世界的健康影响。例如,最近有一篇文章指出,在美国,每年仅来自燃气灶的二氧化氮 "就可能因长期接触二氧化氮而导致 5 万例当前的小儿哮喘"。这一明确的因果关系说法与本刊发表的几篇方法论和评论文章等相悖,反映了(a)未经核实的模型假设,即儿科哮喘负担与二氧化氮大致成正比;以及(b)未经核实的因果关系假设,即假设的暴露与反应之间的比例关系是因果关系。这篇文章没有进行任何因果分析,表明这些假设可能是真实的。文章没有说明减少燃气灶的二氧化氮暴露量会降低小儿哮喘风险。文章的主要参考文献没有报告二氧化氮与小儿哮喘之间存在明显的关联,更不用说因果关系了。因此,基本数据表明,在美国,由燃气灶引发的小儿哮喘病例数量与零无异。这凸显了在公共健康风险评估中严格验证建模假设和因果关系声明的必要性,以确保为决策提供科学合理的基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Challenging unverified assumptions in causal claims: Do gas stoves increase risk of pediatric asthma?

The use of unverified models for risk estimates and policy recommendations can be highly misleading, as their predictions may not reflect real-world health impacts. For example, a recent article states that NO2 from gas stoves “likely causes ∼50,000 cases of current pediatric asthma from long-term NO2 exposure alone” annually in the United States. This explicitly causal claim, which is contrary to several methodology and review articles published in this journal, among others, reflects both (a) An unverified modeling assumption that pediatric asthma burden is approximately proportional to NO2; and (b) An unverified causal assumption that the assumed proportionality between exposure and response is causal. The article is devoid of any causal analysis showing that these assumptions are likely to be true. It does not show that reducing NO2 exposure from gas stoves would reduce pediatric asthma risk. Its key references report no significant associations – let alone causation – between NO2 and pediatric asthma. Thus, the underlying data suggests that the number of pediatric asthma cases caused by gas stoves in the United States is indistinguishable from zero. This highlights the need to rigorously validate modeling assumptions and causal claims in public health risk assessments to ensure scientifically sound foundations for policy decisions.

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来源期刊
Global Epidemiology
Global Epidemiology Medicine-Infectious Diseases
CiteScore
5.00
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0.00%
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22
审稿时长
39 days
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