卢森堡癌症死亡率趋势：24 年描述性研究（1998-2021 年）

IF 2.4 3区医学 Q3 ONCOLOGY

Cancer Epidemiology Pub Date : 2024-08-31 DOI:10.1016/j.canep.2024.102648

Allini Mafra , Jérôme Weiss , Stéphanie Saleh , Guy Weber , Claudine Backes

{"title":"卢森堡癌症死亡率趋势：24 年描述性研究（1998-2021 年）","authors":"Allini Mafra , Jérôme Weiss , Stéphanie Saleh , Guy Weber , Claudine Backes","doi":"10.1016/j.canep.2024.102648","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Cancer, the second most common cause of death worldwide, is projected to cause 17 million deaths by 2045. Epidemiological studies on cancer play a vital role in understanding cancer burden impact and formulating control plans. This study aimed to analyse the changes in cancer mortality rates within Luxembourg from 1998 to 2021 by sex and age.</p></div><div><h3>Methods</h3><p>Data on cancer-related deaths were extracted from Luxembourg's National Registry of Death Causes (1998–2021), and the corresponding population data were analysed. Age-standardized mortality rates (ASRs) per 100,000 individuals were calculated and adjusted to the European standard population. To identify significant changes in cancer mortality over time, the Average Annual Percentage Changes (AAPC) method was used.</p></div><div><h3>Results</h3><p>We identified 23,750 cancer-related deaths, resulting in an ASR of 152.86 per 100,000 people per year. Lung cancer was the most common cancer-related case of death in men and in both sexes combined. In women, breast cancer was the most common cancer death. Significant decreases in the ASR over time were observed for both sexes. Sex-specific cancers, such as prostate (AAPC: −2.7) and breast (AAPC: −1.0) cancers, also exhibited significant decreasing trends in mortality. In the evaluation by life stage, stability or significant decreases were observed for women, men and both sexes, however significant increases were observed in late adulthood women in laryngeal and lung cancer (AAPC: 3.9 and 1.8, respectively). The trend patterns observed during 1998–2021 were largely consistent with those seen when excluding the COVID-19 pandemic year of 2020.</p></div><div><h3>Conclusion</h3><p>Our study provides a comprehensive analysis of mortality trends by cancer type in Luxembourg, contributing to the understanding of cancer epidemiology and informing healthcare policy and planning. This highlights the importance of targeted public health interventions as such early detection and screening programs and continued advancements in cancer treatment.</p></div>","PeriodicalId":56322,"journal":{"name":"Cancer Epidemiology","volume":"93 ","pages":"Article 102648"},"PeriodicalIF":2.4000,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1877782124001279/pdfft?md5=8ad8aa0682ee15113723adae414225a2&pid=1-s2.0-S1877782124001279-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Cancer mortality trends in Luxembourg: A 24-year descriptive study (1998–2021)\",\"authors\":\"Allini Mafra , Jérôme Weiss , Stéphanie Saleh , Guy Weber , Claudine Backes\",\"doi\":\"10.1016/j.canep.2024.102648\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Cancer, the second most common cause of death worldwide, is projected to cause 17 million deaths by 2045. Epidemiological studies on cancer play a vital role in understanding cancer burden impact and formulating control plans. This study aimed to analyse the changes in cancer mortality rates within Luxembourg from 1998 to 2021 by sex and age.</p></div><div><h3>Methods</h3><p>Data on cancer-related deaths were extracted from Luxembourg's National Registry of Death Causes (1998–2021), and the corresponding population data were analysed. Age-standardized mortality rates (ASRs) per 100,000 individuals were calculated and adjusted to the European standard population. To identify significant changes in cancer mortality over time, the Average Annual Percentage Changes (AAPC) method was used.</p></div><div><h3>Results</h3><p>We identified 23,750 cancer-related deaths, resulting in an ASR of 152.86 per 100,000 people per year. Lung cancer was the most common cancer-related case of death in men and in both sexes combined. In women, breast cancer was the most common cancer death. Significant decreases in the ASR over time were observed for both sexes. Sex-specific cancers, such as prostate (AAPC: −2.7) and breast (AAPC: −1.0) cancers, also exhibited significant decreasing trends in mortality. In the evaluation by life stage, stability or significant decreases were observed for women, men and both sexes, however significant increases were observed in late adulthood women in laryngeal and lung cancer (AAPC: 3.9 and 1.8, respectively). The trend patterns observed during 1998–2021 were largely consistent with those seen when excluding the COVID-19 pandemic year of 2020.</p></div><div><h3>Conclusion</h3><p>Our study provides a comprehensive analysis of mortality trends by cancer type in Luxembourg, contributing to the understanding of cancer epidemiology and informing healthcare policy and planning. This highlights the importance of targeted public health interventions as such early detection and screening programs and continued advancements in cancer treatment.</p></div>\",\"PeriodicalId\":56322,\"journal\":{\"name\":\"Cancer Epidemiology\",\"volume\":\"93 \",\"pages\":\"Article 102648\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2024-08-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1877782124001279/pdfft?md5=8ad8aa0682ee15113723adae414225a2&pid=1-s2.0-S1877782124001279-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cancer Epidemiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1877782124001279\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer Epidemiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1877782124001279","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

背景癌症是全球第二大常见死因，预计到 2045 年将导致 1700 万人死亡。癌症流行病学研究在了解癌症负担影响和制定控制计划方面发挥着至关重要的作用。本研究旨在分析1998年至2021年卢森堡按性别和年龄划分的癌症死亡率变化情况。方法从卢森堡国家死因登记处（1998-2021年）中提取与癌症相关的死亡数据，并分析相应的人口数据。计算了每10万人的年龄标准化死亡率（ASR），并根据欧洲标准人口进行了调整。为了确定癌症死亡率随时间推移而发生的重大变化，我们采用了年均百分比变化法（AAPC）。肺癌是男性和女性中最常见的癌症相关死亡病例。在女性中，乳腺癌是最常见的癌症死亡病例。随着时间的推移，男女两性的 ASR 都有显著下降。前列腺癌（美国癌症协会：-2.7）和乳腺癌（美国癌症协会：-1.0）等性别特异性癌症的死亡率也呈显著下降趋势。在按生命阶段进行的评估中，观察到女性、男性和两性的死亡率保持稳定或显著下降，但观察到成年晚期妇女的喉癌和肺癌死亡率显著上升（美国癌症协会：分别为 3.9 和 1.8）。1998-2021年期间观察到的趋势模式与排除2020年COVID-19流行年后观察到的趋势模式基本一致。结论：我们的研究对卢森堡按癌症类型划分的死亡率趋势进行了全面分析，有助于了解癌症流行病学，为医疗保健政策和规划提供信息。这凸显了有针对性的公共卫生干预措施的重要性，如早期检测和筛查计划以及癌症治疗的持续进步。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Cancer mortality trends in Luxembourg: A 24-year descriptive study (1998–2021)

Background

Cancer, the second most common cause of death worldwide, is projected to cause 17 million deaths by 2045. Epidemiological studies on cancer play a vital role in understanding cancer burden impact and formulating control plans. This study aimed to analyse the changes in cancer mortality rates within Luxembourg from 1998 to 2021 by sex and age.

Methods

Data on cancer-related deaths were extracted from Luxembourg's National Registry of Death Causes (1998–2021), and the corresponding population data were analysed. Age-standardized mortality rates (ASRs) per 100,000 individuals were calculated and adjusted to the European standard population. To identify significant changes in cancer mortality over time, the Average Annual Percentage Changes (AAPC) method was used.

Results

We identified 23,750 cancer-related deaths, resulting in an ASR of 152.86 per 100,000 people per year. Lung cancer was the most common cancer-related case of death in men and in both sexes combined. In women, breast cancer was the most common cancer death. Significant decreases in the ASR over time were observed for both sexes. Sex-specific cancers, such as prostate (AAPC: −2.7) and breast (AAPC: −1.0) cancers, also exhibited significant decreasing trends in mortality. In the evaluation by life stage, stability or significant decreases were observed for women, men and both sexes, however significant increases were observed in late adulthood women in laryngeal and lung cancer (AAPC: 3.9 and 1.8, respectively). The trend patterns observed during 1998–2021 were largely consistent with those seen when excluding the COVID-19 pandemic year of 2020.

Conclusion

Our study provides a comprehensive analysis of mortality trends by cancer type in Luxembourg, contributing to the understanding of cancer epidemiology and informing healthcare policy and planning. This highlights the importance of targeted public health interventions as such early detection and screening programs and continued advancements in cancer treatment.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Cancer Epidemiology 医学-肿瘤学

CiteScore

4.50

自引率

3.80%

发文量

200

审稿时长

39 days

期刊介绍： Cancer Epidemiology is dedicated to increasing understanding about cancer causes, prevention and control. The scope of the journal embraces all aspects of cancer epidemiology including: • Descriptive epidemiology • Studies of risk factors for disease initiation, development and prognosis • Screening and early detection • Prevention and control • Methodological issues The journal publishes original research articles (full length and short reports), systematic reviews and meta-analyses, editorials, commentaries and letters to the editor commenting on previously published research.