tDCS 用于治疗精神病临床高危青少年的阴性症状：可行性研究

IF 2.1 4区医学 Q3 CLINICAL NEUROLOGY

Psychiatry Research: Neuroimaging Pub Date : 2024-08-30 DOI:10.1016/j.pscychresns.2024.111879

Paul D. Metzak , Marilena M. DeMayo , Kali Brummitt , Signe Bray , Frank MacMaster , Ashley Harris , Alexander McGirr , Jean Addington

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引用次数: 0

摘要

处于精神病临床高风险（CHR）的青少年经常会出现消极症状。本研究探讨了将 tDCS 与 CBT 结合使用以治疗 5 名临床高危青少年的阴性症状的可行性。我们试图确定该方案是否可行，因为需要在三周内重复访问，并确定是否可以包括神经生物学变化的测量，包括急性期和三周刺激后的测量。研究结果表明，该方案对这些青少年来说是可行的，纳入核磁共振成像扫描会话可获得高质量的数据。

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tDCS for the treatment of negative symptoms in youth at clinical-high-risk for psychosis: A feasibility study

Negative symptoms are often found in youth at clinical high risk (CHR) for psychosis. The present study explored the feasibility of using tDCS in conjunction with CBT in the treatment of negative symptoms in 5 youths at CHR. We sought to determine whether the protocol was feasible given the requirement for repeated visits over a three-week period, and to determine if measures of neurobiological change could be included, both acutely and following three weeks of stimulation. The results from this study suggest that the protocol is feasible for these youth, and the inclusion of MRI scanning sessions yielded good quality data.

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来源期刊

Psychiatry Research: Neuroimaging 医学-精神病学

CiteScore

3.80

自引率

0.00%

发文量

审稿时长

22.5 weeks

期刊介绍： The Neuroimaging section of Psychiatry Research publishes manuscripts on positron emission tomography, magnetic resonance imaging, computerized electroencephalographic topography, regional cerebral blood flow, computed tomography, magnetoencephalography, autoradiography, post-mortem regional analyses, and other imaging techniques. Reports concerning results in psychiatric disorders, dementias, and the effects of behaviorial tasks and pharmacological treatments are featured. We also invite manuscripts on the methods of obtaining images and computer processing of the images themselves. Selected case reports are also published.