骨质疏松症不完全椎体爆裂性骨折椎体后凸成形术的原发性稳定性:生物力学研究。

IF 3.8 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Oliver Riesenbeck, Niklas Czarnowski, Michael Johannes Raschke, Simon Oeckenpöhler, René Hartensuer
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引用次数: 0

摘要

背景:我们的研究旨在从生物力学角度评估使用椎体后凸成形术来稳定椎体不完全爆裂性骨折的创伤后节段不稳定性。研究方法研究对象为 14 个骨质疏松脊柱死后样本(Th11-L3)。首先,在我们的机器人脊柱测试仪上采集原始多节段运动学数据,并进行三维运动分析,作为每个样本的基线。然后,在椎体 L1 上产生不完全爆裂性骨折,并重新进行运动学测试。在对骨折椎体进行椎体后凸成形术后,再次检测其主要稳定性。结果:最初,在不完全爆裂性骨折发生后,所有三个运动方向(伸屈、侧倾、轴向旋转)的活动范围都明显增加,这证明了创伤后的不稳定性。相邻节段的原生状态没有明显变化。从放射学角度看,骨折椎体的高度也明显下降。通过椎体后凸成形术,创伤性不稳定性明显降低。然而,原生运动学并未恢复。结论:虽然在我们的体外模型中,通过椎体后凸成形术可显著降低创伤后节段不稳定性,但却无法重建原生运动学,仍然存在明显的不稳定性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Primary Stability of Kyphoplasty in Incomplete Vertebral Body Burst Fractures in Osteoporosis: A Biomechanical Investigation.

Background: The objective of our study was to biomechanically evaluate the use of kyphoplasty to stabilize post-traumatic segmental instability in incomplete burst fractures of the vertebrae. Methods: The study was performed on 14 osteoporotic spine postmortem samples (Th11-L3). First, acquisition of the native multisegmental kinematics in our robot-based spine tester with three-dimensional motion analysis was set as a baseline for each sample. Then, an incomplete burst fracture was generated in the vertebral body L1 with renewed kinematic testing. After subsequent kyphoplasty was performed on the fractured vertebral body, primary stability was examined again. Results: Initially, a significant increase in the range of motion after incomplete burst fracture generation in all three directions of motion (extension-flexion, lateral tilt, axial rotation) was detected as proof of post-traumatic instability. There were no significant changes to the native state in the adjacent segments. Radiologically, a significant loss of height in the fractured vertebral body was also shown. Traumatic instability was significantly reduced by kyphoplasty. However, native kinematics were not restored. Conclusions: Although post-traumatic segmental instability was significantly reduced by kyphoplasty in our in vitro model, native kinematics could not be reconstructed, and significant instability remained.

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来源期刊
Bioengineering
Bioengineering Chemical Engineering-Bioengineering
CiteScore
4.00
自引率
8.70%
发文量
661
期刊介绍: Aims Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal: ● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings. ● Manuscripts regarding research proposals and research ideas will be particularly welcomed. ● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. ● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds. Scope ● Bionics and biological cybernetics: implantology; bio–abio interfaces ● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices ● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc. ● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology ● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering ● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation ● Translational bioengineering
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