小儿肝移植受者重返重症监护室的风险因素。

Q4 Medicine
Lei-Qing Gao, Li-Ting Qi, Jing Jin, Yan-Fen Gu, Ye-Feng Lu
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引用次数: 0

摘要

摘要] 目的 探讨小儿肝移植受者返回重症监护病房(ICU)的风险因素,为术后临床决策提供参考。方法 对2019年至2021年在上海交通大学医学院附属仁济医院接受肝移植手术并返回ICU的所有小儿患者资料进行回顾性分析。比较两组患者的基本信息、转出ICU当天的生命体征和实验室指标、免疫抑制剂和药物浓度,并进行多变量Logistic回归分析,探讨小儿肝移植受者返回ICU的风险因素。结果 小儿肝移植受者返回重症监护室的比例为4.36%,48小时内返回的比例为16.00%,返回的主要原因包括呼吸系统并发症、腹腔感染和肝血管闭塞。多变量逻辑回归分析显示,术后输红细胞(OR=4.554,95%CI=1.743-11.901,P=0.002)和血清尿酸水平高(OR=1.005,95%CI=1.001-1.009,P=0.014)是返回 ICU 的危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Risk Factors for Returning of Pediatric Liver Transplant Recipients to the Intensive Care Unit].

Objective To explore the risk factors for the returning of pediatric liver transplant recipients to the intensive care unit (ICU) and provide reference for the clinical decision-making after surgery. Methods A retrospective analysis was conducted with the information of all the pediatric patients who underwent liver transplantation in Ren Ji Hospital,Shanghai Jiao Tong University School of Medicine and were returned to the ICU from 2019 to 2021.The patients returned to the ICU during hospitalization and the reasons for the return were recorded.Each patient of ICU return was matched with three pediatric patients who did not return to the ICU during hospitalization.The basic information,the vital signs and laboratory indicators on the day of transfer from ICU,immunosuppressants and drug concentrations were compared between the two groups.Multivariate Logistic regression analysis was performed to explore the risk factors for the returning of pediatric liver transplant recipients to the ICU. Results The returning rate of pediatric liver transplant recipients to the ICU was 4.36%,and it was 16.00% within 48 h.The main reasons for the return included respiratory complications,abdominal infections,and hepatic vascular occlusion.Multivariate Logistic regression analysis showed that post-operative red blood cell transfusion (OR=4.554,95%CI=1.743-11.901,P=0.002) and high serum level of uric acid (OR=1.005,95%CI=1.001-1.009,P=0.014) were the risk factors for returning to the ICU.High diastolic blood pressure (OR=0.922,95%CI=0.885-0.960,P<0.001) and high total protein level (OR=0.937,95%CI=0.891-0.986,P=0.012) were the protective factors for returning to the ICU. Conclusion Post-operative red blood cell transfusion and high serum level of uric acid are independent risk factors for the returning of pediatric liver transplant recipients to the ICU.

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来源期刊
中国医学科学院学报
中国医学科学院学报 Medicine-Medicine (all)
CiteScore
0.60
自引率
0.00%
发文量
6813
期刊介绍: Acta Academiae Medicinae Sinicae was founded in February 1979. It is a comprehensive medical academic journal published in China and abroad, supervised by the Ministry of Health of the People's Republic of China and sponsored by the Chinese Academy of Medical Sciences and Peking Union Medical College. The journal mainly reports the latest research results, work progress and dynamics in the fields of basic medicine, clinical medicine, pharmacy, preventive medicine, biomedicine, medical teaching and research, aiming to promote the exchange of medical information and improve the academic level of medicine. At present, the journal has been included in 10 famous foreign retrieval systems and their databases [Medline (PubMed online version), Elsevier, EMBASE, CA, WPRIM, ExtraMED, IC, JST, UPD and EBSCO-ASP]; and has been included in important domestic retrieval systems and databases [China Science Citation Database (Documentation and Information Center of the Chinese Academy of Sciences), China Core Journals Overview (Peking University Library), China Science and Technology Paper Statistical Source Database (China Science and Technology Core Journals) (China Institute of Scientific and Technological Information), China Science and Technology Journal Paper and Citation Database (China Institute of Scientific and Technological Information)].
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