Akshya Kumar Sahoo , Priyadarsan Parida , Manoj Kumar Panda , K. Muralibabu , Ashima Sindhu Mohanty
{"title":"多肿瘤分析仪(MTA-20-55):从核磁共振成像图像中对检测到的脑肿瘤进行高效分类的网络","authors":"Akshya Kumar Sahoo , Priyadarsan Parida , Manoj Kumar Panda , K. Muralibabu , Ashima Sindhu Mohanty","doi":"10.1016/j.bbe.2024.06.003","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>Brain cancer<span>, one of the leading causes of mortality worldwide, is caused by brain tumors. Early diagnosis of tumors and predicting their progression can help doctors to save lives. In this article, we have designed an automated approach for locating and classifying tumors from MRI images. The novelties of the research work include the following two stages: Developing an encoder-decoder type 20-Layered </span></span>deep neural network<span><span> (DNN) named MultiTumor Analyzer (MTA-20) with 15 down-sampling layers and 4 up-sampling layers, the segmentation is performed in the initial stage. Here, we have adhered a Leaky ReLU activation function<span> instead of ReLU which learn a parameter with negative values that may have valuable information which is essential specifically for </span></span>image segmentation. Further, a 55-layered DNN using </span></span>multistage<span> feature fusion is developed in the second stage of the work for the classification of localized tumors. The classification is performed using developed MultiTumor Analyzer (MTA-55) DNN with Softmax classifier. The efficacy of the designed network is validated using highly cited quantitative measures such as accuracy, sensitivity, specificity, dice similarity coefficient (DSC), precision, and F1-measure. It is observed that the proposed MTA-20 DNN attains the average accuracy, sensitivity, specificity, DSC, and precision of 99.2 %, 94.6 %, 99.3 %, 88 %, and 82.5 % respectively against seven state-of-the-art techniques. Also, it is found that, the proposed MTA-55 DNN provides the overall accuracy, recall, specificity, F1-measure, precision, and DSC of 99.8 %, 99.633 %, 99.844 %, 99.659 %, 99.689 %, and 99.656 % respectively as compared to thirteen state-of-the-art techniques. These results corroborate the superiority of the proposed technique.</span></p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"44 3","pages":"Pages 617-634"},"PeriodicalIF":5.3000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"MultiTumor Analyzer (MTA-20–55): A network for efficient classification of detected brain tumors from MRI images\",\"authors\":\"Akshya Kumar Sahoo , Priyadarsan Parida , Manoj Kumar Panda , K. Muralibabu , Ashima Sindhu Mohanty\",\"doi\":\"10.1016/j.bbe.2024.06.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span>Brain cancer<span>, one of the leading causes of mortality worldwide, is caused by brain tumors. Early diagnosis of tumors and predicting their progression can help doctors to save lives. In this article, we have designed an automated approach for locating and classifying tumors from MRI images. The novelties of the research work include the following two stages: Developing an encoder-decoder type 20-Layered </span></span>deep neural network<span><span> (DNN) named MultiTumor Analyzer (MTA-20) with 15 down-sampling layers and 4 up-sampling layers, the segmentation is performed in the initial stage. Here, we have adhered a Leaky ReLU activation function<span> instead of ReLU which learn a parameter with negative values that may have valuable information which is essential specifically for </span></span>image segmentation. Further, a 55-layered DNN using </span></span>multistage<span> feature fusion is developed in the second stage of the work for the classification of localized tumors. The classification is performed using developed MultiTumor Analyzer (MTA-55) DNN with Softmax classifier. The efficacy of the designed network is validated using highly cited quantitative measures such as accuracy, sensitivity, specificity, dice similarity coefficient (DSC), precision, and F1-measure. It is observed that the proposed MTA-20 DNN attains the average accuracy, sensitivity, specificity, DSC, and precision of 99.2 %, 94.6 %, 99.3 %, 88 %, and 82.5 % respectively against seven state-of-the-art techniques. Also, it is found that, the proposed MTA-55 DNN provides the overall accuracy, recall, specificity, F1-measure, precision, and DSC of 99.8 %, 99.633 %, 99.844 %, 99.659 %, 99.689 %, and 99.656 % respectively as compared to thirteen state-of-the-art techniques. These results corroborate the superiority of the proposed technique.</span></p></div>\",\"PeriodicalId\":55381,\"journal\":{\"name\":\"Biocybernetics and Biomedical Engineering\",\"volume\":\"44 3\",\"pages\":\"Pages 617-634\"},\"PeriodicalIF\":5.3000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biocybernetics and Biomedical Engineering\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0208521624000445\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biocybernetics and Biomedical Engineering","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0208521624000445","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
MultiTumor Analyzer (MTA-20–55): A network for efficient classification of detected brain tumors from MRI images
Brain cancer, one of the leading causes of mortality worldwide, is caused by brain tumors. Early diagnosis of tumors and predicting their progression can help doctors to save lives. In this article, we have designed an automated approach for locating and classifying tumors from MRI images. The novelties of the research work include the following two stages: Developing an encoder-decoder type 20-Layered deep neural network (DNN) named MultiTumor Analyzer (MTA-20) with 15 down-sampling layers and 4 up-sampling layers, the segmentation is performed in the initial stage. Here, we have adhered a Leaky ReLU activation function instead of ReLU which learn a parameter with negative values that may have valuable information which is essential specifically for image segmentation. Further, a 55-layered DNN using multistage feature fusion is developed in the second stage of the work for the classification of localized tumors. The classification is performed using developed MultiTumor Analyzer (MTA-55) DNN with Softmax classifier. The efficacy of the designed network is validated using highly cited quantitative measures such as accuracy, sensitivity, specificity, dice similarity coefficient (DSC), precision, and F1-measure. It is observed that the proposed MTA-20 DNN attains the average accuracy, sensitivity, specificity, DSC, and precision of 99.2 %, 94.6 %, 99.3 %, 88 %, and 82.5 % respectively against seven state-of-the-art techniques. Also, it is found that, the proposed MTA-55 DNN provides the overall accuracy, recall, specificity, F1-measure, precision, and DSC of 99.8 %, 99.633 %, 99.844 %, 99.659 %, 99.689 %, and 99.656 % respectively as compared to thirteen state-of-the-art techniques. These results corroborate the superiority of the proposed technique.
期刊介绍:
Biocybernetics and Biomedical Engineering is a quarterly journal, founded in 1981, devoted to publishing the results of original, innovative and creative research investigations in the field of Biocybernetics and biomedical engineering, which bridges mathematical, physical, chemical and engineering methods and technology to analyse physiological processes in living organisms as well as to develop methods, devices and systems used in biology and medicine, mainly in medical diagnosis, monitoring systems and therapy. The Journal''s mission is to advance scientific discovery into new or improved standards of care, and promotion a wide-ranging exchange between science and its application to humans.