多肿瘤分析仪(MTA-20-55):从核磁共振成像图像中对检测到的脑肿瘤进行高效分类的网络

IF 5.3 2区 医学 Q1 ENGINEERING, BIOMEDICAL
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引用次数: 0

摘要

脑肿瘤是导致全球死亡的主要原因之一。早期诊断肿瘤并预测其发展可以帮助医生挽救生命。在本文中,我们设计了一种从核磁共振成像图像中定位和分类肿瘤的自动方法。研究工作的新颖之处包括以下两个阶段:开发一个名为 "多肿瘤分析器(MTA-20)"的编码器-解码器型 20 层深度神经网络(DNN),其中有 15 个下采样层和 4 个上采样层,在初始阶段进行分割。在这里,我们采用了 Leaky ReLU 激活函数,而不是 ReLU,后者学习的参数为负值,而负值可能包含对图像分割至关重要的有价值信息。此外,在工作的第二阶段,我们开发了一种使用多级特征融合的 55 层 DNN,用于对局部肿瘤进行分类。分类是利用开发的多肿瘤分析器(MTA-55)DNN 和 Softmax 分类器进行的。所设计网络的功效通过准确度、灵敏度、特异性、骰子相似系数(DSC)、精确度和 F1 测量等高引用率的定量指标进行了验证。据观察,与七种最先进的技术相比,所提出的 MTA-20 DNN 的平均准确度、灵敏度、特异性、骰子相似系数和精确度分别达到 99.2%、94.6%、99.3%、88% 和 82.5%。此外,研究还发现,与 13 种最先进的技术相比,所提出的 MTA-55 DNN 的总体准确率、召回率、特异性、F1-measure、精确度和 DSC 分别为 99.8 %、99.633 %、99.844 %、99.659 %、99.689 % 和 99.656 %。这些结果证明了所建议技术的优越性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
MultiTumor Analyzer (MTA-20–55): A network for efficient classification of detected brain tumors from MRI images

Brain cancer, one of the leading causes of mortality worldwide, is caused by brain tumors. Early diagnosis of tumors and predicting their progression can help doctors to save lives. In this article, we have designed an automated approach for locating and classifying tumors from MRI images. The novelties of the research work include the following two stages: Developing an encoder-decoder type 20-Layered deep neural network (DNN) named MultiTumor Analyzer (MTA-20) with 15 down-sampling layers and 4 up-sampling layers, the segmentation is performed in the initial stage. Here, we have adhered a Leaky ReLU activation function instead of ReLU which learn a parameter with negative values that may have valuable information which is essential specifically for image segmentation. Further, a 55-layered DNN using multistage feature fusion is developed in the second stage of the work for the classification of localized tumors. The classification is performed using developed MultiTumor Analyzer (MTA-55) DNN with Softmax classifier. The efficacy of the designed network is validated using highly cited quantitative measures such as accuracy, sensitivity, specificity, dice similarity coefficient (DSC), precision, and F1-measure. It is observed that the proposed MTA-20 DNN attains the average accuracy, sensitivity, specificity, DSC, and precision of 99.2 %, 94.6 %, 99.3 %, 88 %, and 82.5 % respectively against seven state-of-the-art techniques. Also, it is found that, the proposed MTA-55 DNN provides the overall accuracy, recall, specificity, F1-measure, precision, and DSC of 99.8 %, 99.633 %, 99.844 %, 99.659 %, 99.689 %, and 99.656 % respectively as compared to thirteen state-of-the-art techniques. These results corroborate the superiority of the proposed technique.

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来源期刊
CiteScore
16.50
自引率
6.20%
发文量
77
审稿时长
38 days
期刊介绍: Biocybernetics and Biomedical Engineering is a quarterly journal, founded in 1981, devoted to publishing the results of original, innovative and creative research investigations in the field of Biocybernetics and biomedical engineering, which bridges mathematical, physical, chemical and engineering methods and technology to analyse physiological processes in living organisms as well as to develop methods, devices and systems used in biology and medicine, mainly in medical diagnosis, monitoring systems and therapy. The Journal''s mission is to advance scientific discovery into new or improved standards of care, and promotion a wide-ranging exchange between science and its application to humans.
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