晚期诊断的播散性肺结核:病例报告

IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Luis Alejandro Rodriguez-Hidalgo, Diana Cecilia Ruíz Caballero, Amalia Vega-Fernandez
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引用次数: 0

摘要

导言:肺结核最常累及肺部,但感染也可通过淋巴血行播散累及其他器官。播散性肺结核的临床表现多种多样。诊断很困难,因为临床表现多种多样,50%以上的患者发病较晚,因为微生物检测依赖于分枝杆菌培养和辅助组织病理学的侵入性程序:一名 30 岁的男性患者因左手腕剧烈疼痛入院,既往曾接受过 7 个月的糖皮质激素治疗。他的胸膜、左手腕关节和左侧睾丸出现了肺结核的临床症状,检查证实存在结核杆菌。他接受了手腕和睾丸手术,并接受了易感结核治疗。同时,他还被诊断出患有先天性库欣病、慢性贫血和慢性非活动性直肠炎等后遗症:由于临床表现无特异性、确诊工具和专业评估不及时,诊断播散性结核十分困难。长期使用全身性皮质类固醇可能是导致结核病播散的原因之一。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Late diagnosis of disseminated tuberculosis: A case report.

Introduction: The lungs are most commonly involved in tuberculosis, but infection can also involve other organs through lymphohematogenous dissemination. The clinical presentation of disseminated tuberculosis is variable. Diagnosis is difficult, because clinical manifestations are diverse, more than 50% of patients present late, because microbiological testing relies on invasive procedures for mycobacterial culture and supportive histopathology.

Case report: A 30-year-old male patient, deprived of his liberty, with no co-morbidities, was admitted to the hospital for severe pain in the left wrist, with a previous history of having received systemic glucocorticoids for 7 months. He developed clinical symptoms of pulmonary tuberculosis, in the pleura, in the joint of the left wrist and in the left testicle, and tests confirmed the presence of M. tuberculosis. He underwent surgery on the wrist and testicle and was also treated for susceptible tuberculosis. Concomitant sequelae of iatrogenic Cushing's disease, chronic anemia and chronic inactive proctitis were diagnosed.

Conclusions: Diagnosis of disseminated tuberculosis was difficult due to the non-specific clinical picture, limitations of confirmatory diagnostic tools and timely specialized evaluations. Prolonged use of systemic corticosteroids may have played a role in the dissemination of tuberculosis.

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来源期刊
Medwave
Medwave MEDICINE, GENERAL & INTERNAL-
CiteScore
2.60
自引率
8.30%
发文量
50
审稿时长
12 weeks
期刊介绍: Medwave is a peer-reviewed, biomedical and public health journal. Since its foundation in 2001 (Volume 1) it has always been an online only, open access publication that does not charge subscription or reader fees. Since January 2011 (Volume 11, Number 1), all articles are peer-reviewed. Without losing sight of the importance of evidence-based approach and methodological soundness, the journal accepts for publication articles that focus on providing updates for clinical practice, review and analysis articles on topics such as ethics, public health and health policy; clinical, social and economic health determinants; clinical and health research findings from all of the major disciplines of medicine, medical science and public health. The journal does not publish basic science manuscripts or experiments conducted on animals. Until March 2013, Medwave was publishing 11-12 numbers a year. Each issue would be posted on the homepage on day 1 of each month, except for Chile’s summer holiday when the issue would cover two months. Starting from April 2013, Medwave adopted the continuous mode of publication, which means that the copyedited accepted articles are posted on the journal’s homepage as they are ready. They are then collated in the respective issue and included in the Past Issues section.
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