{"title":"用于替换耳膜的电纺氧化石墨烯/聚合物纳米复合材料","authors":"","doi":"10.1016/j.coco.2024.102048","DOIUrl":null,"url":null,"abstract":"<div><p>The development of structures and devices with enhanced acousto-mechanical properties is a topic of interest in engineering, especially in the biomedical field. A case study is the reconstruction of the tympanic membrane after partial or complete damage, such as from chronic suppurative otitis media, which is the leading cause of infectious diseases in children. In this work, we developed graphene-oxide (GO) nanocomposite polymeric scaffolds fabricated via electrospinning to assess their potential suitability as substitutes of the eardrum. To evaluate the structural influence of GO on the fibrous mesh, we performed a characterization in terms of wettability, mechanical properties, and surface morphology. Moreover, a finite-element model of the middle ear was employed to assess the acousto-mechanical behavior of the eardrum upon application of the developed scaffolds. We observed that GO influenced the morphology of the fibrous scaffolds by increasing the mean diameter of the fibers, their stiffness and strength, while decreasing the water contact angle, thus making the structures more hydrophilic. From the acoustic standpoint, the simulations showed that GO does not significantly affect sound transmission, except for PVDF-based structures, for which GO slightly improves the behavior only up to 2 kHz, but with a suboptimal performance at higher frequencies. Our results open to the development of fibrous nanocomposite polymeric scaffolds with an enhanced acoustic behavior for structural applications not limited to bioengineering.</p></div>","PeriodicalId":10533,"journal":{"name":"Composites Communications","volume":null,"pages":null},"PeriodicalIF":6.5000,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2452213924002390/pdfft?md5=07e069fb28e75279af95b85383775489&pid=1-s2.0-S2452213924002390-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Electrospun graphene oxide/polymeric nanocomposites for eardrum replacements\",\"authors\":\"\",\"doi\":\"10.1016/j.coco.2024.102048\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The development of structures and devices with enhanced acousto-mechanical properties is a topic of interest in engineering, especially in the biomedical field. A case study is the reconstruction of the tympanic membrane after partial or complete damage, such as from chronic suppurative otitis media, which is the leading cause of infectious diseases in children. In this work, we developed graphene-oxide (GO) nanocomposite polymeric scaffolds fabricated via electrospinning to assess their potential suitability as substitutes of the eardrum. To evaluate the structural influence of GO on the fibrous mesh, we performed a characterization in terms of wettability, mechanical properties, and surface morphology. Moreover, a finite-element model of the middle ear was employed to assess the acousto-mechanical behavior of the eardrum upon application of the developed scaffolds. We observed that GO influenced the morphology of the fibrous scaffolds by increasing the mean diameter of the fibers, their stiffness and strength, while decreasing the water contact angle, thus making the structures more hydrophilic. From the acoustic standpoint, the simulations showed that GO does not significantly affect sound transmission, except for PVDF-based structures, for which GO slightly improves the behavior only up to 2 kHz, but with a suboptimal performance at higher frequencies. Our results open to the development of fibrous nanocomposite polymeric scaffolds with an enhanced acoustic behavior for structural applications not limited to bioengineering.</p></div>\",\"PeriodicalId\":10533,\"journal\":{\"name\":\"Composites Communications\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":6.5000,\"publicationDate\":\"2024-08-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2452213924002390/pdfft?md5=07e069fb28e75279af95b85383775489&pid=1-s2.0-S2452213924002390-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Composites Communications\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2452213924002390\",\"RegionNum\":2,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATERIALS SCIENCE, COMPOSITES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Composites Communications","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2452213924002390","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, COMPOSITES","Score":null,"Total":0}
Electrospun graphene oxide/polymeric nanocomposites for eardrum replacements
The development of structures and devices with enhanced acousto-mechanical properties is a topic of interest in engineering, especially in the biomedical field. A case study is the reconstruction of the tympanic membrane after partial or complete damage, such as from chronic suppurative otitis media, which is the leading cause of infectious diseases in children. In this work, we developed graphene-oxide (GO) nanocomposite polymeric scaffolds fabricated via electrospinning to assess their potential suitability as substitutes of the eardrum. To evaluate the structural influence of GO on the fibrous mesh, we performed a characterization in terms of wettability, mechanical properties, and surface morphology. Moreover, a finite-element model of the middle ear was employed to assess the acousto-mechanical behavior of the eardrum upon application of the developed scaffolds. We observed that GO influenced the morphology of the fibrous scaffolds by increasing the mean diameter of the fibers, their stiffness and strength, while decreasing the water contact angle, thus making the structures more hydrophilic. From the acoustic standpoint, the simulations showed that GO does not significantly affect sound transmission, except for PVDF-based structures, for which GO slightly improves the behavior only up to 2 kHz, but with a suboptimal performance at higher frequencies. Our results open to the development of fibrous nanocomposite polymeric scaffolds with an enhanced acoustic behavior for structural applications not limited to bioengineering.
期刊介绍:
Composites Communications (Compos. Commun.) is a peer-reviewed journal publishing short communications and letters on the latest advances in composites science and technology. With a rapid review and publication process, its goal is to disseminate new knowledge promptly within the composites community. The journal welcomes manuscripts presenting creative concepts and new findings in design, state-of-the-art approaches in processing, synthesis, characterization, and mechanics modeling. In addition to traditional fiber-/particulate-reinforced engineering composites, it encourages submissions on composites with exceptional physical, mechanical, and fracture properties, as well as those with unique functions and significant application potential. This includes biomimetic and bio-inspired composites for biomedical applications, functional nano-composites for thermal management and energy applications, and composites designed for extreme service environments.