用于监测金纳米粒子上硫醇分子自组装的单纳米粒子电化学碰撞。

IF 4.9 3区工程技术 Q1 CHEMISTRY, ANALYTICAL

Biosensors-Basel Pub Date : 2024-08-15 DOI:10.3390/bios14080393

Yiyan Bai

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引用次数: 0

摘要

准确了解小分子在纳米粒子（NPs）上的自组装动力学可以更好地控制功能化 NPs 的大小和结构。本文开发了一种基于单纳米粒子电化学碰撞（SNEC）的方法，在单粒子水平上监测6-巯基-1-己醇（6-MCH）和1-己硫醇（MCH）在金纳米粒子上的自组装过程，并精确研究其自组装动力学。结果表明，两者的自组装过程都是由快速吸附和缓慢重组组成。然而，由于极性较差，MCH 的吸附速率明显低于 6-MCH 的吸附速率。值得注意的是，6-MCH 在金纳米粒子上的快速吸附符合扩散控制的 Langmuir 模型。因此，所提出的基于 SNEC 的方法可以作为研究功能化 NPs 自组装机制的一种补充方法。

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Single-Nanoparticle Electrochemical Collision for Monitoring Self-Assembly of Thiol Molecules on Au Nanoparticles.

A precise understanding of the self-assembly kinetics of small molecules on nanoparticles (NPs) can give greater control over the size and architecture of the functionalized NPs. Herein, a single-nanoparticle electrochemical collision (SNEC)-based method was developed to monitor the self-assembly processes of 6-mercapto-1-hexanol (6-MCH) and 1-hexanethiol (MCH) on Au NPs at the single-particle level, and to investigate the self-assembly kinetics exactly. Results showed that the self-assembly processes of both consisted of rapid adsorption and slow recombination. However, the adsorption rate of MCH was significantly lower than that of 6-MCH due to the poorer polarity. Also noteworthy is that the rapid adsorption of 6-MCH on Au NPs conformed to the Langmuir model of diffusion control. Hence, the proposed SNEC-based method could serve as a complementary method to research the self-assembly mechanism of functionalized NPs.

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来源期刊

Biosensors-Basel Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry

CiteScore

6.60

自引率

14.80%

发文量

983

审稿时长

11 weeks

期刊介绍： Biosensors (ISSN 2079-6374) provides an advanced forum for studies related to the science and technology of biosensors and biosensing. It publishes original research papers, comprehensive reviews and communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation or experimental procedure, if unable to be published in a normal way, can be deposited as supplementary electronic material.