羧基疗法以及羧基疗法与特定化学换肤相结合的疗法对黑眼圈血管和色素成分的影响。

IF 1.9 4区 医学 Q3 DERMATOLOGY
Clinical, Cosmetic and Investigational Dermatology Pub Date : 2024-08-23 eCollection Date: 2024-01-01 DOI:10.2147/CCID.S469708
Anna Kołodziejczak, Helena Rotsztejn
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引用次数: 0

摘要

目的:特别关注与黑色素有关的色素沉着(黑眼圈、光老化)和血管性眼圈(通常位于泪沟)的改善。本研究旨在客观评估羧基疗法以及羧基疗法与乳糖酸(20%,pH 值为 2.1)或阿魏酸(14%,pH 值为 4.0-5.0)和抗坏血酸(12%)相结合的治疗方案对眼部皮肤缺陷的影响:对 39 名白种人进行了五次羧基疗法系列治疗(右眼区域)和五次羧基疗法与选定的化学换肤相结合的眼周皮肤治疗(左眼区域)。疗效根据 Mexameter 探头测量的参数(MI 和 EI)进行评估。测量在泪沟和下眼睑中部进行:结果:我们发现,在不同的测量点上,一系列羧基疗法(右侧)对 EI 参数有显著的统计学影响:P 结论:这项研究提供了客观证据,证明单纯的羧基疗法和羧基疗法结合酸类在减轻黑眼圈,尤其是泪沟血管性黑眼圈方面的有效性。乳糖酸、阿魏酸和抗坏血酸可作为安全的补充剂来加强虹吸疗法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Impact of Carboxytherapy and Treatments Combining Carboxytherapy and Selected Chemical Peels on Vascular and Pigmentary Components of the Dark Circles.

Objective: Particular attention is given to the enhancement of melanin-related pigmentation (dark circles, photoaging) and vascular circles, which are commonly located in the tear trough. The objective of the study is to provide an objective evaluation of the impact of carboxytherapy and the treatment regimen combining carboxytherapy with lactobionic acid (20%, pH 2.1) or ferulic acid (14%, pH 4.0-5.0) and ascorbic acid (12%) on skin defects in the eye area.

Materials and methods: A group of 39 Caucasian people were subjected to a series of five carboxytherapy treatments (right eye area) and five treatments combining carboxytherapy with a selected chemical peel for the skin around the eyes (left eye area). The efficacy of therapy was assessed based on parameters (MI and EI) measured with the Mexameter probe. Measurements were made in the tear trough and the middle of the lower eyelid.

Results: We demonstrated that a series of carboxytherapy (right side) significantly statistically influenced the EI parameter (in different measurement points: P <0.0001, P = 0.015, P = 0.002), which reflects the intensity of vascular circles under the eyes. Improvement of this parameter by 7.2 units was also shown in the tear trough in 82.1% of participants after the application of carboxytherapy combined with acids (left side) on the valley of tears for this parameter (EI). Lactobionic acid and carboxytherapy were associated with a statistically significant improvement (P = 0.011) in the tear trough. In this study, a reduction in the combined pigmentation (MI plus EI) for both the right and left sides (p = 0.001 and p = 0.015, respectively) was observed.

Conclusion: The study provides objective evidence for the effectiveness of sole carboxytherapy and carboxytherapy combined with acids in the reduction of dark circles, in particular vascular circles in the tear trough. Lactobionic acid, ferulic acid, and ascorbic acid can be used as safe supplements to enhance carboxytherapy.

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来源期刊
CiteScore
2.80
自引率
4.30%
发文量
353
审稿时长
16 weeks
期刊介绍: Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.
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