重塑血气胸治疗：低剂量胸膜腔内纤维蛋白溶解疗法有望成为一种替代疗法。

IF 0.8 Q4 RESPIRATORY SYSTEM

Respirology Case Reports Pub Date : 2024-08-26 eCollection Date: 2024-08-01 DOI:10.1002/rcr2.70012

Mas Fazlin Mohamad Jailaini, Yusra Hashim, Mohamed Faisal Abdul Hamid

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引用次数: 0

摘要

长期以来，手术排空一直是治疗血气胸的标准方法。然而，有些患者并不适合手术治疗。最近，胸膜腔内纤维蛋白溶解疗法（IPFT）成为治疗潴留性血气胸的有效替代疗法。本病例报告描述了两名不适合手术的潴留性血气胸患者在本中心成功接受了 IPFT 治疗。由于合并症和整体功能状况，这两名患者都被认为不适合手术。他们接受了三个周期的 IPFT 治疗，每个周期使用 2.5 毫克阿替普酶。这种治疗方法有效地排出了潴留的血胸，在出院后3个月内实现了完全的放射学缓解，没有出现即刻或延迟的并发症。

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Revamping hemothorax management: The promise of low-dose intrapleural fibrinolytic therapy as an alternative.

Surgical evacuation has long been the standard treatment for hemothorax. However, some patients are not suitable candidates for surgery. Intrapleural fibrinolytic therapy (IPFT) has recently emerged as an effective alternative for managing retained hemothorax. This case report describes two patients with retained hemothorax who were unfit for surgery and were successfully treated with IPFT at our centre. Both patients were deemed unsuitable for surgery due to comorbidities and their overall functional status. They received three cycles of IPFT, each consisting of 2.5 mg of alteplase. This treatment effectively evacuated the retained hemothorax, achieving complete radiological resolution without immediate or delayed complications up to 3 months post-discharge.

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来源期刊

Respirology Case Reports RESPIRATORY SYSTEM-

CiteScore

1.40

自引率

0.00%

发文量

178

审稿时长

8 weeks

期刊介绍： Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.