DNA 折纸力探针揭示了免疫突触中 T 细胞受体的作用力。

IF 38.1 1区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Nature nanotechnology Pub Date : 2024-08-26 DOI:10.1038/s41565-024-01768-1

Tram Thi Hong Le, Byoung Choul Kim

引用次数: 0

摘要

DNA 折纸张力传感器是通过将 DNA 折纸片材与分子张力探针整合在一起而制作的，能够量化 T 细胞受体在膜间连接处相互作用时所产生的机械力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

DNA origami force probes illuminate T cell receptor forces at the immune synapse

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DNA origami force probes illuminate T cell receptor forces at the immune synapse

DNA origami tension sensors, created by integrating DNA origami sheets with molecular tension probes, enable the quantification of mechanical forces involved in T cell receptor interactions at intermembrane junctions.

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来源期刊

Nature nanotechnology 工程技术-材料科学：综合

CiteScore

59.70

自引率

0.80%

发文量

196

审稿时长

4-8 weeks

期刊介绍： Nature Nanotechnology is a prestigious journal that publishes high-quality papers in various areas of nanoscience and nanotechnology. The journal focuses on the design, characterization, and production of structures, devices, and systems that manipulate and control materials at atomic, molecular, and macromolecular scales. It encompasses both bottom-up and top-down approaches, as well as their combinations. Furthermore, Nature Nanotechnology fosters the exchange of ideas among researchers from diverse disciplines such as chemistry, physics, material science, biomedical research, engineering, and more. It promotes collaboration at the forefront of this multidisciplinary field. The journal covers a wide range of topics, from fundamental research in physics, chemistry, and biology, including computational work and simulations, to the development of innovative devices and technologies for various industrial sectors such as information technology, medicine, manufacturing, high-performance materials, energy, and environmental technologies. It includes coverage of organic, inorganic, and hybrid materials.