研究野生动物癌症的途径和方法。

IF 3.5 1区 环境科学与生态学 Q1 ECOLOGY
Mathieu Giraudeau, Orsolya Vincze, Sophie M. Dupont, Tuul Sepp, Ciara Baines, Jean-Francois Lemaitre, Karin Lemberger, Sophie Gentès, Amy Boddy, Antoine M. Dujon, Georgina Bramwell, Valerie Harris, Beata Ujvari, Catherine Alix-Panabières, Stephane Lair, David Sayag, Dalia A. Conde, Fernando Colchero, Tara M. Harrison, Samuel Pavard, Benjamin Padilla-Morales, Damien Chevallier, Rodrigo Hamede, Benjamin Roche, Tamas Malkocs, Athena C. Aktipis, Carlo Maley, James DeGregori, Guillaume Le Loc’h, Frédéric Thomas
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引用次数: 0

摘要

最近几年,野外生态学家和进化生物学家对野生动物肿瘤和癌症的研究兴趣大增。这有助于 "统一健康方法",即研究人、野生动物、家养动物及其不断变化的环境之间的交叉健康问题。尽管如此,野生动物癌症这一新兴领域目前仍受到使用非侵入性采样检测癌症的方法限制。此外,由于怀疑不同物种对癌症的易感性和抵抗力不同,野外生物学家往往难以选择独特的模式物种。在此,我们概述了在非模式生物中开展癌症研究的重要性,并回顾了目前可用来检测、测量和量化野外癌症的方法,以及受人类医学诊断技术启发而开发的新方法需要克服的方法学限制。我们在此提出的方法将有助于了解癌症、癌症发病率的变化、不同物种的肿瘤抑制机制以及癌症与生活史和生理特征之间的联系等方面的常识,从而有希望对抗这一重大疾病。此外,这有望提供有关野生动物癌症的关键信息,由于过去几十年来人类活动的加速变化可能有利于癌症在野生种群中的发展,因此这一点是当务之急。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Approaches and methods to study wildlife cancer

Approaches and methods to study wildlife cancer

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来源期刊
Journal of Animal Ecology
Journal of Animal Ecology 环境科学-动物学
CiteScore
9.10
自引率
4.20%
发文量
188
审稿时长
3 months
期刊介绍: Journal of Animal Ecology publishes the best original research on all aspects of animal ecology, ranging from the molecular to the ecosystem level. These may be field, laboratory and theoretical studies utilising terrestrial, freshwater or marine systems.
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