腱膜补片移植的临床应用和效果:全面回顾。

IF 2.1 4区 医学 Q2 OPHTHALMOLOGY
Indian Journal of Ophthalmology Pub Date : 2024-12-01 Epub Date: 2024-08-14 DOI:10.4103/IJO.IJO_783_24
Rakhi Kusumesh, Alisha Kishore, Anitha Venugopal, Sushmita G Shah, Murugesan Vanathi
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引用次数: 0

摘要

摘要:角膜穿孔如不及时治疗,有可能危及视力。治疗方法取决于穿孔的大小、位置、原因和严重程度。目前有多种方法可供选择,包括组织粘合剂、羊膜移植术(AMG)和角膜移植术。然而,在紧急情况下,供体组织的可用性有限,这构成了一项重大挑战。最近,腱膜修补移植术(TPG)因其自体性质、可用性和无免疫原性而成为一种很有前景的治疗方法。本综述全面概述了 TPG 的各个方面,并附有相关图片。通过使用 "腱膜贴片移植"、"腱膜囊"、"角膜贴片移植"、"羊膜 "和 "角膜穿孔 "等关键词进行文献检索,共获得 37 篇文章,并纳入本综述。TPG适用于角膜组织退化导致穿孔、即将穿孔或脱膜的病例,病变范围为2至6毫米。对于较大的穿孔,可结合 AMG 或组织粘合剂对手术进行修改。术后,移植物会发生特征性变化,包括上皮化和胶原沉积,从而形成厚厚的疤痕。可能会出现上皮化延迟、伤口渗漏和移植物开裂等并发症。据报道,TPG 的成功率很高,从 74% 到 87% 不等。不过,TPG 可能会导致视觉效果不理想,尤其是当移植物位于中心位置时,就需要进行角膜移植手术以恢复视觉。总之,TPG 是一种安全且经济有效的技术,可用于恢复角膜变薄症和角膜穿孔的结构完整性,尤其是在无法获得供体组织的紧急情况下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical application and outcome of Tenon's patch graft: A comprehensive review.

Corneal perforations are potentially sight-threatening conditions if not promptly treated. Management depends on the size, location, cause, and severity of the perforation. Various methods, including tissue adhesives, amniotic membrane grafting (AMG), and keratoplasty, are available. However, the limited availability of donor tissue in emergencies poses a significant challenge. Recently, Tenon's patch grafting (TPG) has emerged as a promising treatment option due to its autologous nature, availability, and lack of immunogenicity. This review provides a comprehensive overview of various aspects of TPG, along with relevant images. A literature search using keywords such as "Tenon's patch graft," "Tenon's capsule," "corneal patch graft," "amniotic membrane," and "corneal perforations" yielded 37 articles, included in this review. TPG is suitable for cases involving corneal tissue degradation leading to perforation, impending perforation, or descemetocele, with lesion sizes ranging from 2 to 6 mm. For larger perforations, the procedure may be modified by combining it with AMG or tissue adhesives. Postoperatively, the graft undergoes characteristic changes, including epithelialization and collagen deposition, resulting in the formation of a thick scar. Complications such as delayed epithelialization, wound leaks, and graft dehiscence can occur. High success rates have been reported, ranging from 74% to 87%. However, TPG may result in suboptimal visual outcomes, particularly when the graft is centrally located, necessitating future keratoplasty for visual rehabilitation. Overall, TPG is a safe and cost-effective technique for restoring structural integrity in corneal thinning disorders and perforations, especially in emergency settings when donor tissue is unavailable.

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来源期刊
CiteScore
3.80
自引率
19.40%
发文量
1963
审稿时长
38 weeks
期刊介绍: Indian Journal of Ophthalmology covers clinical, experimental, basic science research and translational research studies related to medical, ethical and social issues in field of ophthalmology and vision science. Articles with clinical interest and implications will be given preference.
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