肝硬化患者铜绿假单胞菌相关性腹泻的罕见病例

Case Reports in Hepatology Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI:10.1155/2024/8238951
Malcolm Chapman, Atul Lodh, Joven Tristeza, Alexander Yang
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引用次数: 0

摘要

社区获得性铜绿假单胞菌(PsA)肠炎病例虽然罕见,但也有报道,并且与近期使用抗生素和免疫力低下的宿主有关。在此,我们介绍一名新诊断为酒精性肝硬化的 29 岁免疫功能正常女性患者,她出现血性腹泻,在粪便培养中发现了 PsA。该病例比较特殊,因为患者近期没有抗生素使用史或免疫抑制史。然而,肝硬化患者的免疫功能障碍会导致先天性免疫和获得性免疫的缺陷,从而使我们的患者容易发生 PsA 相关性腹泻。总之,本病例表明,虽然肝硬化患者被认为具有免疫能力,但由于其免疫系统的缺陷,他们很容易在社区感染罕见的感染,如 PsA。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Rare Case of Pseudomonas aeruginosa-Associated Diarrhea in a Cirrhotic Patient.

While rare, cases of community-acquired Pseudomonas aeruginosa (PsA) enterocolitis have been reported and are associated with recent antibiotic use and immunocompromised hosts. Here we present a 29-year-old immunocompetent female with newly diagnosed alcoholic cirrhosis that presents with bloody diarrhea and was found to have PsA in her stool culture. This case is unique as our patient does not have a history of recent antibiotic use or prior history of immunosuppression. However, immune dysfunction in cirrhosis results in defects in both innate and acquired immunity, thus predisposing our patient to PsA-associated diarrhea. Overall, this case showcases that, while considered immunocompetent, cirrhotic patients are predisposed to rare infections such as PsA in the community due to defects in their immune system.

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