基于病因治疗的多学科团队讨论可改善难治性慢性咳嗽的疗效

IF 2.4 Q2 RESPIRATORY SYSTEM
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引用次数: 0

摘要

背景难治性慢性咳嗽(RCC)严重影响患者的生活质量。患者和方法我们通过整合呼吸内科、耳鼻喉科和消化内科,建立了一个多学科团队(MDT)诊所,研究咳嗽的病因和治疗效果。采用咳嗽视觉模拟量表(VAS)、莱斯特咳嗽问卷(LCQ)和反流症状指数(RSI)评分对治疗效果进行量化评估。门诊患者的 RCC 诊断率为 88.7%。RCC的常见病因包括胃食管反流性咳嗽(63.5%)、上气道咳嗽综合征(43.5%)和咳嗽变异性哮喘(14.8%)。经过平均 2.17 ± 1.06 周(周)的治疗后,73.9% 的患者咳嗽得到部分缓解,6.1% 的患者咳嗽完全缓解。治疗前后咳嗽 VAS 评分分别为 6.11 ± 2.02 vs. 3.66 ± 2.22(P < 0.05);治疗前后 LCQ 总分分别为 10.24 ± 3.11 vs. 13.16 ± 3.59(P < 0.05);治疗前后 RSI 评分分别为 15.结论 大多数 RCC 患者的病因可在 MDT 诊所中找到,相当一部分 RCC 患者的咳嗽相关症状可在短期内得到改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multidisciplinary team discussion based on etiological treatment improves refractory chronic cough outcomes

Background

Refractory chronic cough (RCC) causes significant impairments in the life quality of patients. Further research into the identification of etiologies and development of the treatment schedules for RCC is needed.

Patients and methods

We established an multidisciplinary team (MDT) clinic, by integrating respiratory medicine, otorhinolaryngology, and gastroenterology departments, to investigate cough etiologies and the effectiveness of treatment. The therapeutic effect was assessed quantitatively using the Cough Visual Analog Scales (VAS), Leicester Cough Questionnaire (LCQ), and Reflux Symptoms Index (RSI) scores.

Results

In total, 213 patients attending the MDT outpatient clinic were examined, and 115 patients with RCC were included for analysis. The RCC diagnosis rate among the outpatient was 88.7%. Common causes of RCC included gastroesophageal reflux cough (63.5%), upper airway cough syndrome (UACS) (43.5%), and cough variant asthma (CVA) (14.8%). After an average treatment period of 2.17 ± 1.06 weeks (wk), 73.9% of the patients had partial cough remission, and 6.1% had complete cough remission. The cough VAS score before and after treatment was 6.11 ± 2.02 vs. 3.66 ± 2.22 (P < 0.05), respectively; LCQ total score before and after treatment was 10.24 ± 3.11 vs. 13.16 ± 3.59 (P < 0.05), respectively; and RSI score before and after treatment was 15.82 ± 7.01 vs. 10.71 ± 6.64 (P < 0.05), respectively.

Conclusion

The etiologies of most patients with RCC could be identified in the MDT clinic, and the cough-related symptoms of a significant number of patients with RCC improved in a short period.

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来源期刊
Respiratory investigation
Respiratory investigation RESPIRATORY SYSTEM-
CiteScore
4.90
自引率
6.50%
发文量
114
审稿时长
64 days
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