Aaron Yeh-Gorocica , Marco Torres-Castro , Claudia Carrillo-Chan , Alejandro Suarez-Galaz , Melissa Suarez-Galaz , Wilson Moguel-Chin , Alonso Panti-May , Cesar Lugo-Caballero , Henry Puerta-Guardo , Juan Chable-Santos , Pablo Manrique-Saide , Guadalupe Ayora-Talavera , Celia Selem-Salas , Mario Frias-Casas , Antonio Rivero-Juarez
{"title":"墨西哥东南部尤卡坦州捕获的蝙蝠中流行的黄热病病毒和阿尔法病毒","authors":"Aaron Yeh-Gorocica , Marco Torres-Castro , Claudia Carrillo-Chan , Alejandro Suarez-Galaz , Melissa Suarez-Galaz , Wilson Moguel-Chin , Alonso Panti-May , Cesar Lugo-Caballero , Henry Puerta-Guardo , Juan Chable-Santos , Pablo Manrique-Saide , Guadalupe Ayora-Talavera , Celia Selem-Salas , Mario Frias-Casas , Antonio Rivero-Juarez","doi":"10.1016/j.onehlt.2024.100876","DOIUrl":null,"url":null,"abstract":"<div><p><em>Flavivirus</em> (family <em>Flaviviridae</em>) and <em>Alphavirus</em> (family <em>Togaviridae</em>) are mosquito-borne viruses that poses a significant risk to public health worldwide. Examples of these viruses include <em>Dengue virus</em> (DENV) and <em>Zika virus</em> (ZIKV) in the <em>Flavivirus</em> genus, and <em>Chikungunya virus</em> (CHIKV) in the <em>Alphavirus</em> genus. The potential contribution of bats in the mosquito-to-human transmission cycle of these viral genera in the tropics has not been studied. Here, a total of 144 bats belonging to three families (<em>Emballonuridae, Phyllostomidae, and Molossidae</em>) and six species were captured for one year using mist nets in sites with different landscapes (forest and grassland) in the state of Yucatan, southeastern Mexico. Blood samples and rectal and oral swabs were collected to detect <em>Flavivirus</em> and <em>Alphavirus</em> RNA genomes through RT-PCR. <em>Flavivirus</em> RNA was detected in 53 individuals (36.8%; 95% CI: 29.4%–44.9%), and <em>Alphavirus</em> RNA was detected in 59 individuals (40.1%; 95% CI: 33.2%–49.2%). The sequences obtained were consistent with ZIKV and DENV, into the <em>Flavivirus</em>, and CHIKV into the <em>Alphavirus</em> positive samples. The prevalence of both <em>Flavivirus</em> and <em>Alphavirus</em> was higher during the dry season compared with the rainy season. This high positivity rate, highlighted in both <em>Flavivirus</em> and <em>Alphavirus</em>, suggests a potential contribution of bats in the circulation of these viral genera in sylvatic environments. Seasonal variation in viral genera prevalence, with higher prevalence during dry seasons than rainy seasons, may suggest specific viral activity patterns in response to climatic conditions.</p></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100876"},"PeriodicalIF":4.1000,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352771424002027/pdfft?md5=293a86deda0be9101be7f7231a7b12fe&pid=1-s2.0-S2352771424002027-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Prevalence of Flavivirus and Alphavirus in bats captured in the state of Yucatan, southeastern Mexico\",\"authors\":\"Aaron Yeh-Gorocica , Marco Torres-Castro , Claudia Carrillo-Chan , Alejandro Suarez-Galaz , Melissa Suarez-Galaz , Wilson Moguel-Chin , Alonso Panti-May , Cesar Lugo-Caballero , Henry Puerta-Guardo , Juan Chable-Santos , Pablo Manrique-Saide , Guadalupe Ayora-Talavera , Celia Selem-Salas , Mario Frias-Casas , Antonio Rivero-Juarez\",\"doi\":\"10.1016/j.onehlt.2024.100876\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><em>Flavivirus</em> (family <em>Flaviviridae</em>) and <em>Alphavirus</em> (family <em>Togaviridae</em>) are mosquito-borne viruses that poses a significant risk to public health worldwide. Examples of these viruses include <em>Dengue virus</em> (DENV) and <em>Zika virus</em> (ZIKV) in the <em>Flavivirus</em> genus, and <em>Chikungunya virus</em> (CHIKV) in the <em>Alphavirus</em> genus. The potential contribution of bats in the mosquito-to-human transmission cycle of these viral genera in the tropics has not been studied. Here, a total of 144 bats belonging to three families (<em>Emballonuridae, Phyllostomidae, and Molossidae</em>) and six species were captured for one year using mist nets in sites with different landscapes (forest and grassland) in the state of Yucatan, southeastern Mexico. Blood samples and rectal and oral swabs were collected to detect <em>Flavivirus</em> and <em>Alphavirus</em> RNA genomes through RT-PCR. <em>Flavivirus</em> RNA was detected in 53 individuals (36.8%; 95% CI: 29.4%–44.9%), and <em>Alphavirus</em> RNA was detected in 59 individuals (40.1%; 95% CI: 33.2%–49.2%). The sequences obtained were consistent with ZIKV and DENV, into the <em>Flavivirus</em>, and CHIKV into the <em>Alphavirus</em> positive samples. The prevalence of both <em>Flavivirus</em> and <em>Alphavirus</em> was higher during the dry season compared with the rainy season. This high positivity rate, highlighted in both <em>Flavivirus</em> and <em>Alphavirus</em>, suggests a potential contribution of bats in the circulation of these viral genera in sylvatic environments. 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Prevalence of Flavivirus and Alphavirus in bats captured in the state of Yucatan, southeastern Mexico
Flavivirus (family Flaviviridae) and Alphavirus (family Togaviridae) are mosquito-borne viruses that poses a significant risk to public health worldwide. Examples of these viruses include Dengue virus (DENV) and Zika virus (ZIKV) in the Flavivirus genus, and Chikungunya virus (CHIKV) in the Alphavirus genus. The potential contribution of bats in the mosquito-to-human transmission cycle of these viral genera in the tropics has not been studied. Here, a total of 144 bats belonging to three families (Emballonuridae, Phyllostomidae, and Molossidae) and six species were captured for one year using mist nets in sites with different landscapes (forest and grassland) in the state of Yucatan, southeastern Mexico. Blood samples and rectal and oral swabs were collected to detect Flavivirus and Alphavirus RNA genomes through RT-PCR. Flavivirus RNA was detected in 53 individuals (36.8%; 95% CI: 29.4%–44.9%), and Alphavirus RNA was detected in 59 individuals (40.1%; 95% CI: 33.2%–49.2%). The sequences obtained were consistent with ZIKV and DENV, into the Flavivirus, and CHIKV into the Alphavirus positive samples. The prevalence of both Flavivirus and Alphavirus was higher during the dry season compared with the rainy season. This high positivity rate, highlighted in both Flavivirus and Alphavirus, suggests a potential contribution of bats in the circulation of these viral genera in sylvatic environments. Seasonal variation in viral genera prevalence, with higher prevalence during dry seasons than rainy seasons, may suggest specific viral activity patterns in response to climatic conditions.
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