评估 Physalis angulata 根提取物的抗癌潜力和药理作用,作为未来研究的有力候选对象

IF 3.5 Q3 Biochemistry, Genetics and Molecular Biology
Jayachithra Ramakrishna Pillai , Adil Farooq Wali , Pooja Shivappa , Sirajunisa Talath , Sabry M. Attia , Ahmed Nadeem , Muneeb U. Rehman
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引用次数: 0

摘要

最近,通过天然成分预防癌症并发症的研究在全球范围内引起了更多关注。这方面的研究还表明,使用天然成分被认为是减少上述疾病及其后果的一种有前途的策略。近年来,天然资源因其易于获取和安全的特性,成为强有力的抗癌剂。在这方面,我们介绍了使用 Physalis angulata 根的甲醇提取物作为强效候选物的可能性,并应用 LC-MS 来揭示各种植物化合物的存在。Physalis angulata 根所表现出的抗癌潜力及其对微生物群的毒性诱导能力增强了揭示植物化学化合物的兴趣,这些化合物包括苦艾素内酯、姜黄素二聚体 1、Mytilin A、人参皂苷 F1、延胡索苷、Ganoderic acid TQ、Alnustone、Rhamnetin 3-sophoroside、赤霉素 A14 醛、Thiolutin、Euglobal III 和 Epomusenin B。各种宏量和微量营养素的存在表明,昂古拉酸浆是未来针对药理学研究,特别是抗癌研究的重要资源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluating the anti-cancer potential and pharmacological in-sights of Physalis angulata Root Extract as a strong candidate for future research

The research targeting the prevention of complications through natural constituents, instigated by the cancer has recently drawn much more attention over the globe. The research in this direction also revealed that the use of natural constituents would considered a promising strategy for diminishing the aforementioned disease and its consequences. Because of the easy availability and safe nature, the recent years, natural resources as strong anticancer agents. In this regard, here we introduced the possibility of using the methanolic extract of Physalis angulata root as a strong candidate and implemented the applicability of LC-MS to unveil the presence of various phytocompounds. The anticancer potential exhibited by Physalis angulata root followed by its ability to induce toxicity against the microbial population enhanced the interest in unveiling the phytochemical compounds including Absintholide, Curcumin dimer 1, Mytilin A, Ginsenoside F1, Encecalin , Ganoderic acid TQ, Alnustone, Rhamnetin 3-sophoroside, Gibberellin A14 aldehyde, Thiolutin, Euglobal III and Epomusenin B. The presence of various macro and micronutrients suggested that Physalis angulata is a prominent resource for future research targeting pharmacological research, especially anticancer research.

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来源期刊
Journal of Genetic Engineering and Biotechnology
Journal of Genetic Engineering and Biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
5.70
自引率
5.70%
发文量
159
审稿时长
16 weeks
期刊介绍: Journal of genetic engineering and biotechnology is devoted to rapid publication of full-length research papers that leads to significant contribution in advancing knowledge in genetic engineering and biotechnology and provide novel perspectives in this research area. JGEB includes all major themes related to genetic engineering and recombinant DNA. The area of interest of JGEB includes but not restricted to: •Plant genetics •Animal genetics •Bacterial enzymes •Agricultural Biotechnology, •Biochemistry, •Biophysics, •Bioinformatics, •Environmental Biotechnology, •Industrial Biotechnology, •Microbial biotechnology, •Medical Biotechnology, •Bioenergy, Biosafety, •Biosecurity, •Bioethics, •GMOS, •Genomic, •Proteomic JGEB accepts
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